Clinical trials: Adherence, Treatment
Human Immunodeficiency Virus
CARE Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC)
The purpose of this study is to determine whether an intervention (CARE+ Corrections) delivered to HIV-infected detainees within the DC Department of Corrections (DOC) and recently -released ex-detainees in the community can…
- Trial name
- CARE+ (NCT01721226)
- Testing
- Intervention Arm (computer-based CARE+ Corrections tool), Educational video on opiate overdose prevention
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- George Washington University
Compliance Behavior
Beta Glucosylceramide for Treatment of NASH
Oral administration of betaglucosylceramide was shown effective in reducing inflammation in animal models and was found safe in humans.
- Trial name
- NCT02126306
- Testing
- Beta Glucosylceramide
- Volunteers
- 23 people
- Sponsor
- Hadassah Medical Organization
Congestive Heart Failure, Emotions
Researching Emotions And Cardiac Health: Phase III
The focus of this study is to examine the feasibility, acceptability, and preliminary impact of a 12-week, telephone-delivered, positive psychology (PP)-based health behavior intervention in a group of patients with mild to…
- Conditions
- Congestive Heart Failure, Emotions, Patient Compliance
- Trial name
- REACH III (NCT03220204)
- Testing
- PP-based health behavior intervention, MI-based educational control condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Patient Compliance
Effect of Patient Information Leaflet on Working Pattern and Patient Satisfaction Level for Day Care Surgeries.
This study aims to understand the benefits of imparting pre operative instructions through written leaflets. The influence on the number of avoidable postponements and delay is also studied.The study is restricted to patients…
- Trial name
- NCT03011840
- Testing
- Information leaflet
- Volunteers
- 449 people
- Sponsor
- Tata Memorial Hospital
Heart Failure With Normal Ejection Fraction, Sleep Apnea
Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study
This study is designed to demonstrate feasibility of study conduct and that acceptable adherence to adaptive servo-ventilation (ASV) therapy can be achieved in recently hospitalized HFpEF patients with moderate to severe sleep…
- Trial name
- CAT-PEF (NCT03195660)
- Testing
- ASV Therapy
- Where
- 4 sites in United States, Germany
- Volunteers
- 6 people
- Sponsor
- ResMed
Type 1 Diabetes, Type 2 Diabetes
A Study of LY8888AX in Participants Using a Connected Insulin Management Platform
The main purpose of this study is to assess participant adherence and glucose control while using a connected insulin management platform. Approximately 50 participants will be enrolled in each country.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Type 2 Diabetes Treated With Insulin
- Trial name
- NCT05893797
- Testing
- Insulin Lispro, Tempo Smart Button, Dexcom G6 CGM
- Where
- 9 sites in France
- Volunteers
- 36 people
- Sponsor
- Eli Lilly and Company
Risk Behavior, HIV/AIDS
Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and…
- Conditions
- Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
- Trial name
- CHRP-BB (NCT03282890)
- Testing
- CHRP-BB
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Connecticut
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study B)
To assess the effectiveness of social comparison in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02148523
- Testing
- Comparison to peers, Adherence feedback, Electronic pill bottle
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)
The primary objective outcome is the proportion of participants compliant (at least four hours of use per night for all nights) in the Auto Bilevel group compared to the continuous positive airway pressure (CPAP) group after 90…
- Trial name
- BiPAPRescue (NCT02522442)
- Testing
- CPAP, Auto BiLevel
- Where
- 3 sites in United States
- Volunteers
- 51 people
- Sponsor
- Philips Respironics
HIV, AIDS
Personalized Text Messages to Improve Antiretroviral Treatment (ART) Adherence in HIV+ Methamphetamine Users
Methamphetamine (METH) is a debilitating and frequently abused substance that is often comorbid with HIV infection. HIV+ persons with current METH abuse or dependence (HIV+/METH+) have several characteristics, in addition to…
- Trial name
- iTAB (NCT01317277)
- Testing
- individualized Texting for Adherence Building (iTAB), Psychoeducation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Glaucoma
Improve Glaucoma Medication Adherence
The proposed study is a randomized controlled trial enrolling Veterans with medically treated glaucoma who report less than 100% adherence to the prescribed glaucoma therapy.
- Trial name
- MAGIC (NCT03052257)
- Testing
- Educational - glaucoma, Dose monitoring and reminder, Educational - general
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Cardiovascular Disease
Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies
The purpose of this randomized clinical trial is to determine whether two low-intensity, technology based interventions, when compared to each other and to usual care, improve adherence to selected medications that are used to…
- Trial name
- PATIENT (NCT01251757)
- Testing
- Interactive Voice Recognition (IVR) phone calls, Educational mailings and follow-up for nonadherence
- Where
- 3 sites in United States
- Volunteers
- 21,752 people
- Sponsor
- Kaiser Permanente
Schistosomiasis, Health Education
Health Education Model Led by Community Health Volunteers.
The goal of this intervention study is to investigate the level of knowledge, attitudes, and behaviors of students on schistosomiasis in Pemba Island.
- Trial name
- NCT06312462
- Testing
- health education
- Where
- Tanzania
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Pemba Ministry of Health Zanzibar
Diabetes Mellitus, Type 2, Medication Adherence
The Synergy to Control Emergency Department Hyperglycemia Program for Type 2 Diabetes
A 4 week prospective, randomized controlled study was carried out to assess the impact of a care delivery intervention which focused on blood glucose (BG) management among adults with type 2 diabetes presenting to the Emergency…
- Conditions
- Diabetes Mellitus, Type 2, Medication Adherence, HYPERGLYCEMIA
- Trial name
- STEP-DM (NCT02269098)
- Testing
- Diabetes medication management
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Medstar Health Research Institute
Schizophrenia, Schizoaffective Disorder
Development of a Mobile System for Self-management of Schizophrenia (SOS)
This 2-arm clinical trial piloted a mobile Self-Management of Schizophrenia (SOS) system that administers interventions targeting persistent symptoms of psychosis, social dysfunction, and medication adherence.
- Trial name
- NCT01969500
- Testing
- Mobile Application, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bipolar Disorder, Substance Use Disorders
Intervention for Comorbid Substance Use and Bipolar Disorders
This trial aims to evaluate the effectiveness of a novel intervention for patients with co-occurring bipolar and substance use disorders following a psychiatric hospitalization.
- Trial name
- ITAP (NCT04202393)
- Testing
- Integrated Treatment Adherence Program (ITAP), Safety Assessment and Follow-up Evaluation (SAFE)
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Butler Hospital
Contraception
Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion
The purpose of this study is to determine whether Nitrous Oxide is effective in achieving pain control and satisfaction among nulliparous women getting the intrauterine device (IUD).
- Trial name
- NIUD (NCT02391714)
- Testing
- IUD insertion, Povidone-Iodine, Chlorhexidine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Medication Adherence
Early Prototyping and Usability Testing (ACPS)
The goal of this pilot clinical trial is to refine and test a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions.
- Trial name
- ACPS (NCT05719064)
- Testing
- Adaptive Cell Phone Support
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Hospital Los Angeles
Renal Transplantation
Behavioral Contract Adherence Intervention
There is a critical gap in the knowledge on how to implement effective interventions for renal transplant recipients (RTRs) to improve immunosuppressant therapy (IST) adherence and clinical outcomes.
- Trial name
- NCT01739803
- Testing
- Behavioral Contract
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Tennessee
Glaucoma
Interactive Study to Increase Glaucoma Adherence to Treatment
Study participants who receive the I-SIGHT intervention will have higher rates of glaucoma treatment compliance (e.g., medication-taking and refill compliance, return for clinical follow-up) and more positive eye health outcomes…
- Trial name
- I-SIGHT (NCT00794170)
- Testing
- Telephone and Print based intervention
- Where
- 2 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Emory University