Clinical trials: Adhesion
Retained Products of Conception, Intrauterine Adhesion
Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss
Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications.
- Trial name
- NCT04637373
- Testing
- Hysteroscopy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Hereditary Cancer Syndrome, Hereditary Breast and Ovarian Cancer
Evaluation of the Adhesion to the GENEPY Network
In order to best meet the needs of all those affected by the genetic risk of cancer in our region, it is important to identify the factors likely to influence the course leading to the GENEPY surveillance network.
- Conditions
- Hereditary Cancer Syndrome, Hereditary Breast and Ovarian Cancer, Hereditary Colorectal Endometrial Cancer Syndrome
- Trial name
- GENEPY (NCT03979612)
- Testing
- inclusion of subjects in the GENEPY network
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institut Claudius Regaud
Healthy
Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell)
This is an open-label study. A total of approximately 60 subjects will be randomly assigned to receive either the heat patch (30 subjects) with a temperature probe/skin reference probe or a heat patch (30 subjects) alone.
- Trial name
- NCT02241057
- Testing
- Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell), Temperature Probe
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Dental Caries, Adhesion
Efficiency of Different Modes of Universal Adhesive
The purpose of this study is to evaluate and compare the clinical performance of a Universal adhesive's different application modes.
- Trial name
- NCT04271150
- Testing
- Self-etch, Total-etch
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity
The Effect of Different Adhesion Strategies on the Clinical Success
The study will involve 41 people who regularly seek treatment at clinics. Participants must be in generally good health and be older than eighteen.
- Conditions
- Poor Aesthetic of Existing Restoration of Tooth, Dental Restoration Failure of Marginal Integrity, Unacceptable Morphology of Tooth Restoration, Secondary Caries
- Trial name
- NCT06500546
- Testing
- Treatment of cervical lesions
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postsurgical Adhesion
Effects of Soft Tissue Mobilization on Postsurgical Adhesions, Pain, Lumbopelvic Muscle Functions, Spinal Mobility, and Posture in Postpartum Women With Caesarean Section
Postpartum women with C-section receiving deep and superficial tissue mobilization would have better improvement on pain, lumbopelvic muscle functions, spinal mobility, and posture compare to the superficial tissue mobilization…
- Trial name
- NCT05008315
- Testing
- Myofascial abdominal diaphragm release, Direct focused scar release technique, Direct manipulations to visceral structures
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- YI-JU TSAI
Pneumoperitoneum
CO2 Absorption During Laparoscopy
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia.
- Trial name
- NCT01340989
- Testing
- alteration of the insufflation gas, full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Healthy Adult Participants
A Study to Assess the Bioavailability and Adhesion of Selegiline TDS in Healthy Subjects
The purpose of this research study is to compare the bioavailability and adhesion of a generic Selegiline transdermal system (TDS) against the marketed comparator (EMSAM®) in healthy volunteers.
- Trial name
- NCT07571824
- Testing
- Selegiline TDS 6 mg/24 hours, EMSAM® TDS 6 mg/24 hours
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Corium Innovations, Inc.
Adhesion
LEAFix Adhesion in Healthy Volunteers
This study compares the adhesiveness of the 3M material to be used in the final design.
- Trial name
- NCT05415059
- Testing
- Covatech Stoma bag material
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Polyetheretherketone
Microbial Adhesion to Metallic Versus Non Metallic Surfaces of Bounded Removable Partial Denture
a split mouth randomized clinical trial that compares quantity and quality of bacterial adhesion under both PEEK versus cobalt chromium alloy denture base.
- Trial name
- splitmouth (NCT03008317)
- Testing
- PEEK
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Generic Lidocaine Patch 5% in Healthy, Adult, Human Subjects
An open label, randomized, two-treatment, two-period, single-dose study evaluating the product adhesion in healthy, adult subjects using ZTlido 1.8% Topical System and a generic Lidocaine Patch 5%
- Trial name
- NCT04319926
- Testing
- lidocaine topical system 1.8%, lidocaine patch 5%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Intrauterine Adhesion, Scar
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions
TCRA is an important surgical method to restore normal menstrual cycle and improve the outcome of pregnancy.However, postoperative intrauterine adhesion, uterine cavity deformation and difficulty in normal intimal growth…
- Trial name
- NCT05003869
- Testing
- Scar tissue is removed
- Where
- China
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Lili Cao
Oral Health
L. Brevis CD2 Strain Persistence in Oral Cavity
The aim of this study is to select the optimal conditions for quantification in the oral cavity of Lactobacillus brevis CD2, a probiotic strain contained in a commercially available dietary supplement and to assess its…
- Trial name
- NCT01782079
- Testing
- L. brevis
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Skin (FLACC Scores of Test Subjects) After Tape Removal
Assessment of Wound Care Product Skin Adhesion
The purpose of this exploratory study is to assess the adhesive forces to skin of samples over the period of 24 hours to establish the peel-off measurement method at the Essity study site.
- Trial name
- SWAP (NCT07136870)
- Testing
- Medical tape
- Where
- Sweden
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Healthy
Nasal LPS Challenge in Healthy Volunteers
The purpose of this study is to develop a nasal challenge model that causes a mild degree of inflammation, without causing any pain or symptoms, but that allows us to measure a variety of proteins in nasal secretions which causes…
- Trial name
- NCT02284074
- Testing
- Nasal LPS spray, Experimental: Nasal LPS spray 1µg, Experimental: Nasal LPS spray 10 µg
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Intrauterine Adhesion
Assessment of Uterine Access, Uterine Patency and Intrauterine Adhesions Following Endometrial Ablation
The objective of this study is to gain information concerning the acute and longer-term morphological changes within the uterus following endometrial ablation.
- Trial name
- NCT04824430
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rejoni Inc.
Acne Vulgaris
Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
The aim of this study is to: 1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group 2.
- Trial name
- NCT06340984
- Testing
- Montelukast 10 Mg Oral Tablet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Visual Acuity
Ex-vivo Adhesion of Bacteria to Different Contact Lens Materials
This is a single-site, 4-visit, contralateral, dispensing, open-label, randomized study. Each eligible subject will be randomized into one of two sequence groups to wear two lens types contralaterally (Test on the right eye and…
- Trial name
- NCT04108286
- Testing
- 1-DAY ACUVUE MOIST, DAILIES AQUA COMFORT PLUS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.