Clinical trials: Adhesive Small Intestine Obstruction
Adhesive Small Intestine Obstruction
(Gastrografin Use in Small Bowel Obstruction Caused by Adherences)
Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a very common disease. Any improvement in this field will benefit many patients by reducing the operative rate.
- Trial name
- GUSBOCA (NCT00601809)
- Testing
- traditional conservative treatment (TT), Gastrografin®: G
- Where
- 2 sites in Italy
- Volunteers
- 76 people
- Sponsor
- University of Bologna
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Adhesive Small Bowel Obstruction
Comparison of Outcomes of Management of Bowel Obstruction
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related…
- Trial name
- COMBO (NCT07084441)
- Testing
- Dexamethasone, Supportive Care
- Where
- 4 sites in United States
- Volunteers
- 550 people
- Sponsor
- University of Washington
Adhesive Small Bowel Obstruction
Surgery for Adhesive Small Bowel Obstruction in a Defined Population: a Cohort Study
A cohort study of patients operated for adhesive small bowel obstruction (SBO) during a five-year period
- Trial name
- NCT03534596
- Volunteers
- 402 people
- Sponsor
- Uppsala University
Intestinal Obstruction
Clinical and Financial Impact of an Evidenced-Based Adhesive Small Bowel Obstruction Management Protocol
This research study is for patients with adhesive small bowel obstruction (ASBO). ASBO is a condition in which the small intestine gets blocked due to scars called adhesions.
- Trial name
- NCT02928458
- Testing
- Omnipaque, MD-Gastroview
- Where
- United States
- Sponsor
- The Guthrie Clinic
Small Bowel Obstruction, Conservative Management
Radiologic Score and Failure of Conservative Management of Adhesive Small Bowel Obstruction
The management of acute adhesive small bowel obstruction remains challenging for the digestive surgeon. The Bologna guidelines recommend that conservative management of aSBO.
- Conditions
- Small Bowel Obstruction, Conservative Management, Imaging
- Trial name
- PREDIFAIL (NCT05517057)
- Where
- France
- Volunteers
- 279 people
- Sponsor
- University Hospital, Angers
Adhesive Small Bowel Obstruction
Optimizing Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach…
- Trial name
- NCT06182319
- Testing
- Gastrografin, Saline, SBO Treatment Without NG Tubes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Los Angeles
Small Bowel Obstruction Adhesion
Place of Nasogastric Tube in Uncomplicated Adhesive Small Bowel Obstruction
Acute adhesive Small Bowel Obstruction (ASBO) is a public health issue: this is the 3rd cause of hospitalization in Digestive Surgery Departments, 20-30% of patients will be operated, the mortality rate per episode is 3%, the…
- Trial name
- BOWNTI (NCT06347120)
- Testing
- nasogastric tube, NOM without NGT insertion
- Where
- France
- Volunteers
- 504 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Small Bowel Obstruction
Water-Soluble Contrast Induced Intestinal Stimulation for the Treatment of Small Bowel Obstruction: A Feasibility Study
Small bowel obstruction (SBO) is common yet, how to best manage it remains unknown. One approach is to administer water soluble oral contrast (WSC) and the obtain x-rays to determine how well the bowel is functioning.
- Trial name
- NCT07099300
- Testing
- Abdominal Radiography
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Small Bowel Obstruction, Intestinal Pseudo-Obstruction
Predicting NOM Failure in Bowel Obstruction
"This study aims to collect data on patients with small bowel obstruction (SBO) admitted to hospitals in France and Italy from May 2022 to October 2024 to develop a deep convolutional neural network (DCNN) model.
- Trial name
- NCT06711107
- Where
- France
- Volunteers
- 370 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Small Bowel Obstruction
Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO)
Mini abstract : Altogether 100 patients with 117 episodes of ASBO were randomized into control and gastrografin groups. Eight episodes in eight patients were excluded.
- Trial name
- NCT00738855
- Testing
- Oral Gastrografin, Nothing per os
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Surgery-Induced Tissue Adhesion, Surgical Adhesions
National Snapshot Study Adhesive Small Bowel Obstruction (ASBO)
Over 63-90% of patients develop peritoneal adhesions after abdominal or pelvic surgery. Which makes it the most common complication after abdominal or pelvic surgery.
- Conditions
- Surgery-Induced Tissue Adhesion, Surgical Adhesions, Adhesion, Tissue
- Trial name
- NCT03786159
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Radboud University Medical Center
Adhesive Small Bowel Obstruction
Elective Adhesiolysis vs. a Wait-and-see Policy to Prevent Recurrences After Conservative Treatment of Adhesive Small Bowel Obstruction
Rationale: Adhesive small bowel obstruction (aSBO) is a frequent surgical emergency, associated with 3-8% hospital mortality and a high risk of recurrence (20% at two years of follow-up).
- Trial name
- AWARE (NCT06777446)
- Testing
- Elective Adhesionlysis, Adhesion barrier
- Where
- 14 sites in Belgium, Netherlands
- Volunteers
- 380 people
- Sponsor
- Radboud University Medical Center
Small Bowel Adhesion, Small Bowel Obstruction
Low-osmolar Water Soluble Contrast Agent in Management of Adhesive Small Bowel Obstruction
Adhesive small bowel obstruction (ASBO) is a condition that is commonly found in patients with history of abdominal surgery. The management for such condition can be controversial.
- Trial name
- NCT06140173
- Testing
- Low osmolar contrast, Sterile water
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Small Bowel Obstruction, Contrast Media Adverse Reaction
Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction
The goal of this prospective observational study is to evaluate the diagnostic and therapeutic utility of an enteral contrast challenge for pediatric patients with adhesive small bowel obstruction (ASBO). The aims are to 1.
- Trial name
- SBO (NCT06101719)
- Testing
- Enteral contrast challenge
- Where
- 9 sites in United States
- Volunteers
- 136 people
- Sponsor
- Children's Hospital Colorado
Small Bowel Obstruction, Small Bowel Adhesion
Short and Prolonged Conservative Treatment in Patients With Adhesive Intestinal Obstruction
This study will compare the results of 24 h conservative treatment and N h conservative treatment of adhesive small bowel obstruction (where N = 72 h minus duration of intestinal obstruction).
- Trial name
- NCT05841069
- Testing
- Adhesiolysis, X-ray examination, Conservative treatment
- Where
- 4 sites in Russia
- Volunteers
- 180 people
- Sponsor
- North-Western State Medical University named after I.I.Mechnikov
SBO - Small Bowel Obstruction
Management of Non Emergency Adhesive Small Bowel Obstruction:
SBO-CHOICE is a prospective, multicenter observational study investigating the management of adhesive small bowel obstruction (ASBO), a condition in which scar tissue (adhesions), usually resulting from previous abdominal…
- Trial name
- SBO- CHOICE (NCT07860177)
- Testing
- Surgical group
- Where
- Italy
- Volunteers
- 690 people
- Sponsor
- Azienda Sanitaria di Firenze
Adhesive Small Bowel Obstruction
Comparison of Outcomes of Management of Bowel Obstruction Pilot Study
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO Pilot) Pilot trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with…
- Trial name
- COMBO Pilot (NCT06817551)
- Testing
- Dexamethasone, Supportive Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Adhesive Small Bowel Obstruction
Comparison of Laparoscopic Surgery Versus Open Surgery in the Treatment of Adhesive Small Bowel Obstruction
Small bowel obstruction is a common reason for surgical admission. Most common reason for small bowel obstruction is adhesions, which account up to 70-80 % of small bowel obstructions.
- Trial name
- NCT01867528
- Testing
- Laparoscopic adhesiolysis, Open adhesiolysis
- Where
- 8 sites in Finland, Italy
- Volunteers
- 102 people
- Sponsor
- Helsinki University Central Hospital