Clinical trials: Adipose Tissue
Polycystic Ovary Syndrome
Subcutaneous Adipose Tissue in Cases With Polycystic Ovarian Syndrome
This study aimed to search whether whole body and subcutaneous adipose tissues increase in PCOS patients and whether these tissues are related to HOMA-IR and plasma adiponectin levels.
- Trial name
- NCT01310569
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Obesity & Overweight, Obesity (Disorder)
Weight Loss and Adipose Tissue Metabolism During Conservative Treatment of Obesity
This prospective observational study investigates weight loss and metabolic changes in adults with obesity undergoing standard clinical diet-induced lifestyle treatment and counseling.
- Trial name
- 4FAT (NCT07456124)
- Testing
- Diet-Induced Weight Loss Program
- Volunteers
- 22 people
- Sponsor
- University of Helsinki
Adiposity
Ectopic Adipose Tissue, Exercise Training and IL-6
Aim: Exercise training improves the risk of cardiometabolic diseases; yet the underlying mechanisms are unclear. Exercise induces release of IL-6 from skeletal muscle.
- Trial name
- NCT02901496
- Testing
- Endurance Exercise Training, Resistance Exercise Training, No Exercise
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Metabolic Syndrome (MetS)
Isoleucine Addition Treatment Effects in a Controlled Diet Study
The primary purpose of this study is to determine whether isoleucine repletion attenuates increases in insulin sensitivity typically observed when people with obesity follow a healthy, low-isoleucine diet.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Metabolic Syndrome (MetS), Obesity & Overweight
- Trial name
- ISOLATE (NCT07329088)
- Testing
- L-Isoleucine, Low-isoleucine diet
- Where
- United States
- Sponsor
- Jean L. Fry
Rotator Cuff Tear
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Main purpose of this study is to evaluate efficacy of allogenic adipose-derived mesenchymal stem cells in treatment of tendon injury.
- Trial name
- NCT02298023
- Testing
- allogenic adipose stem cell injection, fibrin glue/normal saline injection, normal saline injection
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Insulin Sensitivity
The Effect of Breaking Prolonged Sitting on Adipose Tissue and Metabolism
The purpose of this project is to investigate the effect of breaking prolonged sitting on acute adipose tissue and metabolic responses.
- Trial name
- NCT02870088
- Testing
- Prolonged Sitting, Breaking Sitting
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Bath
Breast Cancer
The Women's Healthy Lifestyle Study
This study aims to determine if a motivational interviewing counseling style can help women eat a healthy diet and exercise during breast cancer treatment and beyond.
- Trial name
- NCT00583726
- Testing
- motivational interviewing, written materials only
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Obesity, Metabolic Diseases
Intestinal Permeability in Obesity
In rodents, obesity is associated with changes in tight junctions' structure in small intestine, which impacts intestinal permeability and results in metabolic complications. Few data exist in human.
- Conditions
- Obesity, Metabolic Diseases, Nutrition Disorders, Body Weight
- Trial name
- LEAKY GUT (NCT02292121)
- Testing
- Intestinal permeability, a solution of mannitol and lactitol
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Volunteers
Safety Study of Acellular Adipose Tissue for Soft Tissue Reconstruction
The purpose of this study is to assess the safety and tolerability of acellular adipose tissue (AAT), intended for the repair of soft tissue defects in humans, in healthy volunteers.
- Trial name
- NCT02817984
- Testing
- Acellular Adipose Tissue (AAT)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
NAFLD, Nutrient; Excess
Effects of Dietary Nutrients on Liver and Adipose Tissue Metabolism
In health,adipose tissue stores fat from the diet. If the fat tissue stops storing dietary fat then this increases the chance of it being stored in the liver, which is related to increased risk of heart disease and type 2…
- Trial name
- NCT03090347
- Testing
- Overconsumption of specific dietary nutrient
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease
Effects of VLCKD in Metabolic Syndrome
VLCKD has showed to be an impactful diet on several metabolism aspects and has proven to be useful for preventing and treating diabetes mellitus type 2, overweight, chronic inflammation and fatty liver.
- Conditions
- Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- KETO-MI (NCT05275608)
- Testing
- VLCKD diet with replacing meals, Hypocaloric mediterranean Diet
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Coronary Artery Disease
Characterization of Epicardial and Pericardial Adipose Tissue in Coronary Artery Disease
Human epicardial fat is the true visceral fat depot of the heart, and its regional distribution and physiology is of growing scientific and clinical interest.
- Trial name
- NCT02965625
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Instrument-assisted Soft Tissue Mobilization, Flexibility
Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique on Fascia and Fat Tissue Thickness in Healthy Individuals.
Instrument-assisted soft tissue mobilization (IASTM) technique can be used for non-pathological conditions as it has been shown in previous literature to affect flexibility and normal range of motion.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Flexibility, Fascia, Rehabilitation
- Trial name
- NCT05502497
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hip Infection
Relationship Between Preoperative Subcutaneous Trochanteric Fat Thickness and Postoperative Infection Risk
The effect of preoperative subcutaneous trochanteric fat thickness and trochanteric soft tissue thickness on postoperative infection risk in patients undergoing hemiarthroplasty for femoral neck fracture
- Trial name
- NCT06428760
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Obesity Morbid, Obesity-Associated Insulin Resistance
Role NLRP3 Inflammasome in Weight Loss Following Sleeve Gastrectomy in Morbidly Obese Patients
Epidemiological studies show a very rapid increase in the epidemic of obesity in the Caribbean population. 6 out of 10 adults are overweight and 1 out of 4 is obese. Most are women.
- Trial name
- BARIAMITRI (NCT04814147)
- Testing
- Sleeve gastrectomy
- Where
- Martinique
- Volunteers
- 20 people
- Sponsor
- University Hospital Center of Martinique
Varicose Ulcer
Endovenous Ablation Combined With Fat Grafting for Venous Ulcers
The aim of this trial is to determine if fat grafting may have applicability to venous ulcers by comparing healing and recurrence rates in patients who receive combined fat grafting and endovenous ablation with patients who…
- Trial name
- NCT05241704
- Testing
- Fat grafting, Endovenous ablation of superficial venous reflux
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- National University of Ireland, Galway, Ireland
Cardiovascular Risk Factor
Peri-vascular Adipose Tissue Inflammation Evaluated Using Coronary CT Angiography
The P-VECT Study proposes to test the use of CCTA-derived FAI measurements in a group of patients with coronary artery inflammation, who will receive routinely-used statin and aspirin treatment.
- Trial name
- P-VECT (NCT04181749)
- Testing
- aspirin and atorvastatin
- Where
- 3 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Leicester
Obesity, Diabetes
A Role for Brown Adipose Tissue in Postprandial Thermogenesis?
Brown adipose (fat) tissue (BAT) is a type of fat tissue found in certain small rodents and human babies that is capable of extremely high rates of energy burning.
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT01974778
- Testing
- Meal
- Where
- Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Obesity
Insulin Regulation of Lipolysis and Lipolysis Proteins
These studies will define the abnormalities in the adipocyte proteins that are involved in the failure of insulin to suppress lipolysis normally in humans with upper body obesity and will help discover the mechanism by which…
- Trial name
- NCT03866408
- Testing
- Immediate weight loss, Pioglitazone, Deferred weight loss
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dedifferentiated Liposarcoma
Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma
The primary objective of the study is to determine the safety profile and overall response rate of IPI 504 in patients with advanced dedifferentiated liposarcoma.
- Trial name
- NCT00969917
- Testing
- IPI-504
- Where
- United States
- Sponsor
- Infinity Pharmaceuticals, Inc.