Clinical trials: Adipose Tissue Dysfunction Type 2 Diabetes Mellitus Bariatric Surgery
Diabetes Mellitus Type 2
Adipose Tissue Storage in the Rapid Remission of Hepatic and Cardiac Metabolic Dysfunction After Bariatric Surgery
The present protocol aims to understand and establish whether there is a causal link between adipose tissue metabolic remodeling and Type 2 Diabetes (T2D) remission after bariatric surgery.
- Trial name
- CB5 (NCT05934409)
- Testing
- Bariatric surgery, Nicotinic Acid
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Adipose Tissue Dysfunction Type 2 Diabetes Mellitus Bariatric Surgery
Adipose Tissue Dysfunction in Type 2 Diabetes and Its Reversibility by Bariatric Surgery
ABSTRACT Background: Insulin resistance (IR) plays a major role in the pathogenesis of type 2 diabetes (T2D). Adipose tissue (AT) dysfunction leading to systemic low-grade inflammation and ectopic lipid deposition plays an…
- Trial name
- ADIDYS (NCT05291013)
- Testing
- Gastric byspass
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Odense University Hospital
Obesity and Type 2 Diabetes, Bariatric Patients Undergoing Bariatric Surgery
Regional Adipose Tissue Characteristics in Type II Diabetes
Fat tissue in different parts of the body has different characteristics. Several studies have associated abdominal fat to an increased risk for multiple metabolic diseases, such as type 2 diabetes and cardiovascular disease…
- Conditions
- Obesity and Type 2 Diabetes, Bariatric Patients Undergoing Bariatric Surgery, Adipose Tissue Dysfunction Type 2 Diabetes Mellitus Bariatric Surgery, Adipose Tissue Inflammation
- Trial name
- NCT06599047
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Type 2 Diabetes Mellitus, Insulin Resistance
Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus
The focus of this proposal is to define the mechanism by which bariatric surgery acutely improves insulin sensitivity. Our central hypothesis is that drastically reduced caloric intake early after Bariatric surgery improves the…
- Trial name
- NCT01882036
- Testing
- Gastric Bypass w/ matched hypocaloric diet, Hypocaloric diet
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Minnesota