Clinical trials: Adipose Tissue-derived Stem Cell
Covid19
Study of Intravenous COVI-MSC for Treatment of COVID-19-Induced Acute Respiratory Distress
This is a Phase 2 randomized controlled study to assess the safety and efficacy of COVI-MSC in the setting of current standard of care treatments for COVID-19 infection in hospitalized subjects with acute respiratory distress…
- Trial name
- NCT04903327
- Testing
- COVI-MSC
- Where
- 6 sites in Brazil
- Volunteers
- 43 people
- Sponsor
- Sorrento Therapeutics, Inc.
Chronic Obstructive Pulmonary Disease
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
This will be an open-label, non-randomized multi-center study designed to assess the safety and efficacy of Adipose-derived Stem Cell (ASC) IV implantation.
- Trial name
- NCT02216630
- Testing
- Adipose Derived Stem Cell (ADSC) Therapy
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Kimera Society Inc
Muscle Tear
Safety and Feasibility of ADRCs (Adipose Derived Regenerative Cells) in Patients With Grade II Hamstring Tears
To evaluate the safety and feasibility of adipose-derived regenerative cells injected into tears of the hamstring muscle.
- Trial name
- RECOVER (NCT02045888)
- Testing
- ADRCs prepared by investigational Celution Device
- Where
- 2 sites in United States
- Sponsor
- Cytori Therapeutics
Covid19 Pneumonia
Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia
This study is an open-label, single-arm study to evaluate the safety and efficacy of Astrostem-V, allogenic adipose tissue derived mesenchymal stem cells (AdMSC), in patients with COVID-19 pneumonia.
- Trial name
- NCT04527224
- Testing
- AstroStem-V
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Nature Cell Co. Ltd.
Knee Osteoarthritis
Efficacy and Safety of ELIXCYTE Intra-articular Injection in Subject With Knee Osteoarthritis
This is a Phase III, double-blinded, placebo-controlled, multicenter study to investigate the efficacy and safety of a new study intervention, ELIXCYTE, compared to placebo (normal saline) in subjects with knee osteoarthritis.
- Trial name
- NCT05526001
- Testing
- ELIXCYTE, Saline
- Where
- 4 sites in Taiwan
- Volunteers
- 165 people
- Sponsor
- UnicoCell Biomed CO. LTD
Spinal Cord Injury at C5-C7 Level
Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for Treatment of SCI
This study is expanded access to an Investigational New Drug (IND) for an individual patient with spinal cord injury (SCI) at cervical spine 5-6 (C 5-6) designed to provide access to autologous adipose-derived mesenchymal stem…
- Trial name
- NCT03925649
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences LLC
COVID-19
Efficacy and Safety Study of Allogeneic HB-adMSCs for the Treatment of COVID-19
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) as treatment for patients suspected to have COVID-19.
- Trial name
- NCT04362189
- Testing
- HB-adMSC
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Hope Biosciences Research Foundation
Degenerative Arthritis, Knee Osteoarthritis
A Phase 3 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
The purpose of this study is to investigate the efficacy and safety of autologous Adipose Tissue derived Mesenchymal stem cells (JOINTSTEM®) in patient with severe Knee Osteoarthritis.
- Trial name
- NCT03990805
- Testing
- JOINTSTEM, saline
- Where
- 13 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- R-Bio
Chronic Obstructive Pulmonary Disease
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe and 2) Is treatment effective in improving the health of patients with human Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT01559051
- Testing
- Lipoaspiration with Local anesthesia
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Frailty Syndrome
Study to Assess the Safety and Effects of Autologous Adipose-Derived Stem Cells in Patients With Frailty Syndrome
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the health of patients with human frailty syndrome.
- Trial name
- NCT01501461
- Testing
- Harvesting and implantation of stem cells
- Where
- Mexico
- Sponsor
- Ageless Regenerative Institute
Inflammatory Bowel Diseases
Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) is a group of inflammatory conditions of the small bowel and colon. Main types include Ulcerative Colitis and Crohn's Disease.
- Trial name
- ADcSVF-IBD (NCT02952131)
- Testing
- Lipoaspiration, AD-cSVF, Normal Saline IV
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healeon Medical Inc
Breast Neoplasms, Carcinoma, Ductal, Breast
Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy
A post-marketing study evaluating the transplantation of autologous fat augmented with Adipose Derived Regenerative Cells (ADRCs), in patients with functional and cosmetic breast deformities post segmental mastectomy or…
- Conditions
- Breast Neoplasms, Carcinoma, Ductal, Breast, Mammaplasty, Mastectomy, Segmental, Lumpectomy, Breast Reconstruction,
- Trial name
- RESTORE-2 (NCT00616135)
- Testing
- ADRC-Enhanced Autologous Fat Transplant
- Where
- 5 sites in Belgium, Italy and 2 more
- Volunteers
- 71 people
- Sponsor
- Cytori Therapeutics
Avascular Necrosis of the Femoral Head
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Avascular Necrosis of the Femoral Head
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with avascular necrosis of the femoral head.
- Trial name
- NCT01643655
- Testing
- Autologous Adipose Tissue derived MSCs Transplantation
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- R-Bio
Osteoarthritis, Knee
A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
This study is a double-blind, randomized, controlled study with two arms to evaluate JointStem as a treatment for subjects with osteoarthritis.
- Trial name
- NCT02674399
- Testing
- JointStem, Synvisc-One
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Nature Cell Co. Ltd.
Degenerative Arthritis, Knee Arthritis
Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy After JOINTSTEM Administration
The purpose of this study is to confirm cartilage regeneration through arthroscopy after a single administration of autologous Adipose Tissue derived Mesenchymal stem cells(JOINTSTEM) in patients with degenerative arthritis of…
- Trial name
- NCT04821102
- Testing
- JOINTSTEM, Saline
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- R-Bio
COVID-19
A Randomized, Double-Blind, Single Center, Efficacy and Safety Study of Allogeneic HB-adMSCs Against COVID-19.
Hope Biosciences is conducting a research study of an investigational product called allogeneic adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04348435
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I
Adipose Stem/Stromal Cells in RSD, CRPS, Fibromyalgia
Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), CRPS - Complex Regional Pain Syndrome Type I, Fibromyalgia
- Trial name
- ADcSVF-CRPS (NCT02987855)
- Testing
- Lipoaspiration, ADcSVF isolation, Normal Saline IV
- Where
- 2 sites in United States, Honduras
- Sponsor
- Healeon Medical Inc
Erectile Dysfunction
Autologous Adipose-Derived Stromal Cells Delivered Into the Corpus Cavernous in Patients With Erectile Dysfunction
This will be an open-label, non-randomized, multi-center, patient sponsored study of Adipose-Derived Stromal Vascular Fraction cells (AD-SVF) implantation delivered into the corpus cavernous in patients with Erectile Dysfunction.
- Trial name
- NCT02087397
- Testing
- Liposuction, AD-SVF Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Spinal Cord Injury
Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury
The effect of intrathecal transplantation of autologous adipose tissue derived mesenchymal stem cells in the patients with spinal cord injury, Phase I Clinical study.
- Trial name
- NCT01624779
- Testing
- autologous adipose tissue derived mesenchymal stem cells
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Bukwang Pharmaceutical
Facial Atrophy
Adipose Derived Stem Cells in Facial Fat Grafting
This phase two, randomized, double-blind study is designed to demonstrate the enhanced efficacy of SVF-enriched autologous facial fat grafts, in relation to standard, non-SVF enriched, facial fat grafts by evaluating volumetric…
- Trial name
- SVF (NCT02526576)
- Testing
- Stromal Vasular Fraction, Biopsy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Antria