Clinical trials: Adipose Tissue-derived Stem Cell
ED, Adipose Derived Stem Cells
Can Adipose Derived Regenrative Cells be Used for Treating Erectile Dysfunction After Radical Prostatectomy
The goal of this study was to investigate if adipose derived regenerative cells can be used as a treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT07355530
- Testing
- Adipose-Derived Regenerative Cells
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Osteoarthritis, Knee, Knee Pain
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis
This is a non-surgical trial comparing the clinical and functional outcomes of patients with osteoarthritis treated with Intra-articular injection of Micro Fragmented Adipose Tissue versus conventional therapy of intra-articular…
- Trial name
- NCT03467919
- Testing
- Micro Fragmented Adipose Tissue, Corticosteroid injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Crohn's Fistula
Safety and Efficacy Study of Autologous Cultured Adipose -Derived Stem Cells for the Crohn's Fistula
Up to date, a sure cure for Crohn's fistula has not known and the fistula recurrence rate is high. On 15 October 2008, orphan drug designation was granted by Korea FDA to Anterogen Co. Ltd., for human adipose-derived stem cell.
- Trial name
- NCT00992485
- Testing
- ADIPOPLUS
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Anterogen Co., Ltd.
Low Back Pain
Autologous Adipose Derived Stem Cell Therapy for Intervertebral Disc Degeneration
1. Subject: 10 patients : Chronic low back pain patients with lumbar intervertebral disc degeneration 2. Investigational Product : Autologous adipose derived mesenchymal stem cells plus hyaluronic acid derivatives (Tissuefill) 3.
- Trial name
- NCT02338271
- Testing
- autologous adipose derived mesenchymal stem cell
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Inbo Han
Hereditary Corneal Dystrophy, Keratoconus
Autologous Adipose-Derived Adult Stem Cell Transplantation for Corneal Diseases
Transplantation of cellularized human cornea impregnated and populated by mesenchymal stem cells derived from the patient's adipose tissue.
- Trial name
- A-ADAS-CT-CD (NCT02932852)
- Testing
- Lipoaspiration, Transplantation
- Where
- Lebanon
- Volunteers
- 12 people
- Sponsor
- Vissum, Instituto Oftalmológico de Alicante
Osteoporotic Fractures
Effectiveness of Adipose Tissue Derived Mesenchymal Stem Cells as Osteogenic Component in Composite Grafts
Failure rates of up to 30% are reported after proximal humeral fractures despite angular-stable devices. This may devastate not only the functional outcome but also the independence of elderly patients.
- Trial name
- ROBUST (NCT01532076)
- Testing
- Cellularized composite graft augmentation, Acellular composite graft augmentation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoarthritis Knees
Adipose-tissue-derived Total-Stromal-cells (TOST) Therapy in Knee Osteoarthritis
In this phase II Randomized Clinical Trial (RCT), impacts of a single Intra-articular injection of autologous adipose tissue derive total-stromal-cells (TOST) on knee pain, physical function, stiffness, and cartilage thickness…
- Trial name
- NCT05280002
- Testing
- Adipose Tissue derived Total-Stromal-Cells (TOST)
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Acute Ischemic Stroke
Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke
This is a Phase I/II, randomized, double-blind, placebo-controlled, single/multiple ascending dose clinical study (Investigator-Initiated Trial, IIT) evaluating the safety and efficacy of Human Adipose-Derived Stem Cell Exosomes…
- Trial name
- NCT07398612
- Testing
- Human Adipose-Derived Stem Cell Exosomes
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Liver Cirrhosis
Clinical Trial Study About Human Adipose-Derived Stem Cells in the Liver Cirrhosis
The aim of the investigators study was to investigate the safety and efficacy of autologous ADSCs for the clinical treatment of liver cirrhosis.
- Trial name
- NCT02297867
- Testing
- ADSCs
- Where
- 2 sites in Taiwan
- Volunteers
- 6 people
- Sponsor
- Gwo Xi Stem Cell Applied Technology Co., Ltd.
Critical Limb Ischemia and Peripheral Artery Disease
Administration of Adipose-derived Stem Cells (ASC) in Patient With Critical Limb Ischemia.
Different types of stem cells have recently been studied in clinical trial on ischemic disease of the heart and muscular arteries.
- Trial name
- ACellDREAM2 (NCT03968198)
- Testing
- Autologous ASC (for Adipose-derived Stem/Stroma Cell)
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Toulouse
Periodontitis
Evaluation of Adipose Derived Stem Cells Exo.in Treatment of Periodontitis
The adipose stem cells exosomes will be extracted from adipose stem cells isolated autogenously from the patient to be injected locally into the periodontal pockets in order to evaluate their regenerative effect.
- Trial name
- exosomes (NCT04270006)
- Testing
- adipose derived stem cells exosomes
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Stress Urinary Incontinence
Treatment of Stress Urinary Incontinence in Women With Autologous Adipose-derived Mesenchymal Stem Cells
Treatment of women with stress urinary incontinence using injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel
- Trial name
- NCT04446884
- Testing
- Autologous adipose-derived mesenchymal stem cells, Standard treatment according to the Clinical protocols
- Where
- Belarus
- Volunteers
- 10 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
End Stage Renal Disease (ESRD), Vascular Access Complication
Autologous Adipose Derived Mesenchymal Stem Cells (AMSC) in Reducing Hemodialysis Arteriovenous Fistula Failure
The aim of this phase 1 study is to determine the role of autologous adipose derived mesenchymal stem cells in the reduction of hemodialysis arteriovenous fistula failure when applied during the time of surgical creation.
- Trial name
- NCT02808208
- Testing
- Single Application of Adipose Derived Mesenchymal Stem Cells (AMSC), Two Applications of Adipose Derived Mesenchymal Stem Cells (AMSC)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Mayo Clinic
Skin, Scar
Therapy of Scars and Cutis Laxa With Autologous Adipose Derived Mesenchymal Stem Cells
The aim of this study is to compare clinical outcomes of patients with large scars or Cutis laxa treated with injections of autologous stromal vascular fraction cells (SVF) and adipose-derived mesenchymal stem cells (ADSC).
- Conditions
- Skin, Scar, Cutis Laxa, Keloid
- Trial name
- 2ABC (NCT03887208)
- Testing
- Laser therapy, Autologous ADSC injection, Normal saline injection
- Where
- 3 sites in Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Refractory Epilepsy
Intrathecal Autologous ADRC Treatment of Autoimmune Refractory Epilepsy
Refractory epilepsies caused by an autoimmune mechanisms lead in children to progressive neurodegeneration. Immunomodulation therapy is effective only in a half of such cases. New approaches are undertaken.
- Trial name
- EPIMSC (NCT03676569)
- Testing
- ADRC transplantation in autoimmune refractory epilepsy
- Volunteers
- 6 people
- Sponsor
- Mossakowski Medical Research Centre Polish Academy of Sciences
Neurotmesis of Peripheral Nerve (Disorder)
Intraoperative ADSC Administration During Nerve Release
The goal of the investigator's observational, nonrandomized, open label study is to investigate the safety and efficacy of autologous adipose derived mesenchymal cells (ADSC) transplantation into the individuals with faiure in…
- Trial name
- NEUROASC (NCT04346680)
- Testing
- ADSC administration
- Volunteers
- 6 people
- Sponsor
- Mossakowski Medical Research Centre Polish Academy of Sciences
Osteoarthritis, Hip
Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA
Will injection(s) of autologous culture-expanded AMSCs be safe and efficacious for treatment of painful Hip OA, and if so, which dosing regimen is most effective?
- Trial name
- NCT03608579
- Testing
- Autologous Adipose Derived Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Knee Osteoarthrosis
Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Adipose tissue derived Mesenchymal Stem cells (ATMSC) will be injected in patients diagnosed with Knee osteoarthrosis
- Trial name
- NCT02966951
- Testing
- Adipose tissue derived mesenchymal stem cell
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- Hanan Jafar
Mesenchymal Stem Cells, Chronic Kidney Diseases
Treatment of Chronic Renal Failure With Adipose Tissue-derived Mesenchymal Stem Cells
To investigate the biological characteristics of adipose tissue-derived mesenchymal stem cells(AMSCs) and its treatment effects on chronic renal failure.
- Conditions
- Mesenchymal Stem Cells, Chronic Kidney Diseases, Renal Interstitial Fibrosis
- Trial name
- NCT03321942
- Testing
- Treatment group, Control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Ischemic Stroke, Adipose Tissue-derived Stem Cell
Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke
This is a multicenter, doble blind, placebo controlled clinical trial to asses de safety and efficacy of intravenous administration of alogenic adipose tissue-derived mesenchymal stem cells in the first four days from acute…
- Conditions
- Ischemic Stroke, Adipose Tissue-derived Stem Cell, Functional Status
- Trial name
- AMASCIS-02 (NCT04280003)
- Testing
- Alogenic adipose tissue-derived stem cells
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz