Clinical trials: Adipose Tissue-derived Stem Cell
Breast Reconstruction, Contour Irregularities
Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose Derived Stem Cells (ADSC) Enriched Fat Grafts
The purpose of this study is to investigate if there is a relationship between the take of fat grafts with and without ADSCs and the presence of specific surface markers on the cells of the stromal vascular fraction.
- Conditions
- Breast Reconstruction, Contour Irregularities, Volume Insufficiency
- Trial name
- NCT01771913
- Testing
- centrifuged fat graft, ADSCs enriched fat graft
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
End Stage Renal Disease
AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses
Researchers are evaluating the safety of allogeneic Adipose Derived Mesenchymal Stem Cells (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its efficacy on improving access maturation and…
- Trial name
- NCT04392206
- Testing
- Adipose Derived Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Houssam Farres, M.D.
COVID-19
Autologous Adipose-derived Stem Cells (AdMSCs) for COVID-19
This is a phase 2 multi-center, double-blind, randomized, placebo-control clinical trial with 200 subjects who have never been infected by COVID-19 (SARS-Cov-2 virus screen test negative, no blood SARS-Cov-2 IgM and IgG…
- Trial name
- NCT04428801
- Testing
- autologous adipose-derived stem cells
- Volunteers
- 200 people
- Sponsor
- Celltex Therapeutics Corporation
Rheumatoid Arthritis
Autologous Adipose Tissue Stromal Vascular Fraction Cells for Rheumatoid Arthritis
Autologous stromal vascular fraction (SVF) injected at 8 and 10 days after extraction is safe and useful procedure in inducing remission of RA in patients resistant to standard DMARD therapy.
- Trial name
- NCT01885819
- Testing
- Autologous stromal vascular fraction cells
- Where
- Panama
- Sponsor
- Translational Biosciences
Adipose-derived Stem Cells, Excimer Light
Adipose-derived Stem Cells Combined With Excimer Light in the Treatment of Stable Vitiligo
This study aimed to assess the efficacy and safety of intradermal injection of adipose-derived stem cells, alone and combined with excimer light in treatment of stable vitiligo.
- Conditions
- Adipose-derived Stem Cells, Excimer Light, Stable Vitiligo
- Trial name
- NCT07690501
- Testing
- Adipose-derived Stem Cells Combined With Excimer Light
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Tanta University
Female Sexual Dysfunction
Investigating the Efficacy of Autologous, Adipose-derived Mesenchymal Stem Cell Therapy for the Treatment of Sexual Function Impairment in Women Aged 40-50
Female Sexual Dysfunction (FSD) represents a critical public health challenge, significantly impacting women's physical, psychological, and social well-being.
- Trial name
- IEAAMSC-W40-50 (NCT06726538)
- Testing
- Intravenous administration of Autologous, adipose-derived mesenchymal stem cells
- Where
- 2 sites in Vietnam
- Volunteers
- 50 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Gingival Recession
Treatment of Gingival Recession Using Mesenchymal Stem Cells
Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel
- Trial name
- NCT04434794
- Testing
- mesenchymal stem cells, standard treatment
- Where
- Belarus
- Volunteers
- 27 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Alzheimer Disease
A Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease
This is a randomized, double-blind, placebo-controlled, parallel-group comparison study in subjects with Alzheimer's Disease. Following first screening period, subjects will be randomly assigned into one of the following arms…
- Trial name
- NCT03117738
- Testing
- AstroStem
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Nature Cell Co. Ltd.
Fecal Incontinence
Safety Study of Autologous Cultured Adipose -Derived Stem Cells for the Fecal Incontinence
Fecal incontinence affects 18.4% adults in the community and greatly impacts quality of life. There's a problem like inconvenience, pain or allergic response in many therapeutic methods such as a surgical operation or material…
- Trial name
- NCT01011686
- Testing
- ANT-SM
- Where
- South Korea
- Sponsor
- Anterogen Co., Ltd.
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Regenerative Injection of Stem Cells or Stem Cell-derived Exosomes for Erectile Dysfunction (RISE)
The goal of this prospective observational study is to evaluate whether injections of stem cells derived from the patient's own fat tissue (adipose tissue) can improve erectile function in men aged 30 to 75 who have erectile…
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- RISE (NCT06605508)
- Testing
- Autologous Adipose Tissue-Derived Stem Cell Injection for Erectile Dysfunction, Stem cell-derived Exosomes Injection for Erectile Dysfunction
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Jumeirah American Clinic
Covid19
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 "Long Haul" Pulmonary Compromise
This is a Phase 1b study to assess the safety and efficacy of COVI-MSC in treating post COVID-19 "long haulers" with pulmonary compromise.
- Trial name
- NCT04909892
- Testing
- COVI-MSC
- Sponsor
- Sorrento Therapeutics, Inc.
Crohn's Fistula
Safety and Efficacy Study of Autologous Cultured Adipose -Derived Stem Cells for the Crohn's Fistula
Up to date, a sure cure for Crohn's fistula does not known and the fistula recurrence rate is high. On 15 October 2008, orphan designation was granted by Korea FDA for human adipose-derived stem cell (ADIPOPLUS) for the treatment…
- Trial name
- NCT01011244
- Testing
- ADIPOPLUS
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Anterogen Co., Ltd.
Anterior Cruciate Ligament Partial Rupture
Effectiveness and Safety of Autologous ADRC for Treatment of Anterior Cruciate Ligament Partial Rupture
Autologous adipose-derived regenerative cells (ADRC) will be extracted using Celution 800/CRS System (Cytori Therapeutics Inc) from a portion of the fat harvested from the patient's front abdominal wall.
- Trial name
- NCT02469792
- Testing
- Liposuction, ADRC isolation, Arthroscopic surgery
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Knee Osteoarthritis
Evaluation of Safety and Exploratory Efficacy of an Autologous Adipose-derived Cell Therapy Product for Treatment of Single Knee Osteoarthritis
The objective of this clinical study is to evaluate the safety of an intraarticular injection of an investigational biologic product (IBP), PSC-01, the patient's own adipose-derived stromal vascular fraction cells (SVF) extracted…
- Trial name
- NCT04043819
- Testing
- PSC-01
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Personalized Stem Cells, Inc.
Lumbar Intervertebral Disc Degeneration
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Lumbar Intervertebral Disc Degeneration
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with lumbar intervertebral disc degeneration.
- Trial name
- NCT01643681
- Testing
- Autologous Adipose Tissue derived MSCs Transplantation
- Where
- South Korea
- Sponsor
- R-Bio
Androgenic Alopecia
The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia
This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of the allogeneic human adipose derived stem cell component extract on androgenic alopecia in relatively healthy adults.
- Trial name
- NCT02594046
- Testing
- stem cell component extract
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Breast Cancer
19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction
Six female patients (>18 years of age, pre-menopausal) who have had loco-regional (lumpectomy and radiation) therapy for breast carcinoma and have been at least one-year disease free will undergo liposuction, the autologous SVF…
- Trial name
- CS-1000 (NCT02035085)
- Testing
- CS-1000 labeled SVF cells
- Where
- United States
- Sponsor
- Johns Hopkins University
Urethral Strictures in Males
Effectiveness and Safety of Autologous Adipose-Derived Regenerative Cells for the Treatment of Urethral Strictures
Autologous adipose-derived regenerative cells (ADRC) extracted using Celution 800/CRS System (Cytori Therapeutics Inc)from a portion of the fat harvested from the patient's front abdominal wall.
- Trial name
- NCT01889888
- Testing
- Submucosal injection of ADRC
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Female Pattern Hair Loss
Successful Treatment of Female Pattern Hair Loss With Injection of Nanofat With and Without Platelet-Rich Plasma
Background: FPHL is a chronic progressive condition that necessitates lifelong management. Over time, patients who respond to conventional therapy may experience a decrease in the effectiveness of their treatment and may require…
- Trial name
- NCT07096323
- Testing
- Nanofat only, Nanofat mixed with PRP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Hair Disease
AGA Biocellular Stem/Stromal Hair Regenerative Study
Purpose The primary objective of this study is to evaluate the safety and efficacy of the use of a biocellular mixture of emulsified adipose-derived tissue stromal vascular fraction (AD-tSVF) and high density platelet-rich plasma…
- Trial name
- STRAAND (NCT02849470)
- Testing
- Intradermal Injection in hair loss, Platelet Rich Plasma, Adipose Derived Stem/Stromal Cells
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Healeon Medical Inc