Clinical trials: Adipose Tissue-derived Stem Cell
Degenerative Arthritis, Knee Arthritis
Follow-up Study for Participants of Jointstem Investigator Initiated Trial by Arthroscopy
This clinical trial is conducted to assess the long-term safety of "jointstem" in patients with degenerative knee arthritis who participated in the previous BS-JS-IIT1 investigator initiated trial.
- Trial name
- NCT04825730
- Testing
- JOINTSTEM
- Volunteers
- 14 people
- Sponsor
- R-Bio
Fecal Incontinence
Treatment of Fecal Incontinence Using Allogenic-Adipose-derived Mesenchymal Stem Cells: A Prospective, Dose Escalation, Randomized, Placebo-controlled, Parallel-group, Single-blind, Single-center Pilot Study
Purpose: The investigators aimed to investigate the safety and efficacy in the treatment of fecal incontinence by injection of ALLO-ASC into the anal sphincter. Method 1. Safety test of allogenic ASCs injection 2.
- Trial name
- NCT02384499
- Testing
- ALLO-ASC injection
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Yonsei University
Rotator Cuff Tear - Partial Thickness
Safety and Efficacy Adipose-Derived Stem Cell Injection Partial Thickness Rotator Cuff Tears
This is a prospective, randomized, multi-site, safety and efficacy study in subjects with rotator cuff injuries. Patients will fall into two categories: treatment group (12 subjects) and non-treatment or control group (six…
- Trial name
- NCT02918136
- Testing
- Adipose derived regenerative cells, Cortisone Injectable
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- InGeneron, Inc.
Skin Rejuvenation, Lipofilling
Effect of Adipose Derived Stem Cells on Survival of Fat as Filler
this research is to study the effect of Adipose Derived Stem Cells on Survival of Fat as Filler
- Trial name
- NCT03965936
- Testing
- lipofilling, lipofilling enriched with adipose tissue derived stem cells
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Skin Rejuvenation
Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation
This study is to evaluate the efficacy and tolerability of autologous adipose tissue derived stem cells in facial rejuvenation.
- Trial name
- NCT03928444
- Testing
- intradermal injection of adipose derived stem cells to one side of the face, intradermal injection of saline to one side of the face
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Vocal Cord Paralysis, Unilateral
Injection Laryngoplasty Using Autologous Fat Enriched With Adipose Derived Regenerative Stem Cells (ADRC)
This is the first Development Safety Update Report prepared for Phase I-IIA Clinical Trial- FIBHGM-ECNC007-2010 (PHASE I / IIA CLINICAL TRIAL, UNICENTRIC, RANDOMIZED, CONTROLLED, TWO PARALLEL-GROUPS, TO EVALUATE THE SAFETY OF A…
- Trial name
- NCT02904824
- Testing
- adipose derived regenerative cells, centrifuged autologous fat
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Rotator Cuff Tear
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Main purpose of this study is to evaluate efficacy of allogenic adipose-derived mesenchymal stem cells in treatment of tendon injury.
- Trial name
- NCT02298023
- Testing
- allogenic adipose stem cell injection, fibrin glue/normal saline injection, normal saline injection
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Urinary Incontinence
Stem Cells Treatment for the Local Urinary Incontinence After a Radical Prostate Cancer Surgery (HULPURO)
The purpose of this study is to evaluate the feasibility and security of the autologous e-ASC for the urinary incontinence after a radical prostate cancer surgery
- Trial name
- FLPURO (NCT01799694)
- Testing
- Inject of Autologous Adipose-derived stem cells
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Preliminary Efficacy of Adipose Derive Stem Cells for Patients With COPD
The purpose of this study is: 1.- to assess the safety and tolerability of autologous adipose derived stem cells (aADSC) administered intravenously in patients with chronic obstructive pulmonary disease, and 2.- to assess if this…
- Trial name
- NCT02161744
- Testing
- ADSCs administration
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Arkansas Heart Hospital
Progressive Hemifacial Atrophy, Romberg's Disease
The Effect of Human Adipose Tissue-derived MSCs in Romberg's Disease
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of adipose tissue derived mesenchymal stem cells (MSCs) in patient with progressive hemifacial atrophy.
- Trial name
- NCT01309061
- Testing
- Autologous Adipose Tissue derived MSCs Transplantation
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- R-Bio
Esophageal Stenosis Acquired
Adipose-derived Stem Cells in Treatment of Esophageal Strictures
The goal of this clinical trial is to examine the effect of injection of adipose tissue derived stem cells in benign esophageal strictures in patients who have previously required at least 10 balloon dilations without…
- Trial name
- NCT07913646
- Testing
- Adipose-derived stem cells and stromal vascular fraction
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Crohn's Disease, Anal Fistula
Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease.
The purpose of this study is to asses the safety and efficacy of adipose-derived adult stem cells from healthy donnors for treatment of complex perianal fistulas in Crohn's disease.
- Trial name
- NCT01372969
- Testing
- Cx601
- Where
- 6 sites in Spain
- Volunteers
- 24 people
- Sponsor
- Tigenix S.A.U.
Perianal Fistula, Primary; Complex
Follow-up Study of Autologous Adipose-derived Stem Cells (ANTG-ASC) for the Complex Fistula (ANTG-ASC-211)
This is an open follow-up clinical trial to evaluate a sustained efficacy and safety of ANTG-ASC injection for 4 months (6 months after final dose injection) after Phase II clinical trial.
- Trial name
- ANTG (NCT01623453)
- Testing
- Autologous adipose derived stem cells(low dose group), Autologous adipose derived stem cells(high dose group)
- Where
- 2 sites in South Korea
- Volunteers
- 6 people
- Sponsor
- Anterogen Co., Ltd.
Knee Osteoarthritis, Hip Osteoarthritis
A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells
This is a prospective, multi-location safety and effectiveness study, and data registry of autologous adult ADRCs generated by the Transpose® RT System in subjects with OA in the shoulder, wrist, knee, hip, or ankle.
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Ankle Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT04405297
- Testing
- Adipose-derived regenerative cells
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sanford Health
ARDS
Adipose-derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome
Currently, there is no proven effective pharmacologic treatment available for patients with the acute respiratory distress syndrome (ARDS).
- Trial name
- NCT01902082
- Testing
- Mesenchymal stem cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shaoxing Second Hospital
Crohn's Fistula
Clinical Study to Evaluate Efficacy and Safety of ASC and Fibringlue or Fibringlue in Patients With Crohn's Fistula
This is a phase III study to evaluate the efficacy and safety of ASC(Autologous Adipose-derived Stem Cells) and Fibringlue or Fibringlue in Patients With Crohn's Fistula.
- Trial name
- NCT04612465
- Testing
- ASC, Fibringlue
- Where
- 4 sites in South Korea
- Volunteers
- 46 people
- Sponsor
- Anterogen Co., Ltd.
Stem Cells, Adult Stem Cells
Safety Study of Stemchymal® in Acute Liver Failure
To investigate the safety of Stemchymal® via intravenous (IV) infusion in acute liver failure (ALF) and acute on chronic liver failure (ACLF) patients.
- Conditions
- Stem Cells, Adult Stem Cells, Acute Liver Failure, Acute-On-Chronic Liver Failure
- Trial name
- ALF (NCT03629015)
- Testing
- Stemchymal®
- Where
- Taiwan
- Sponsor
- Steminent Biotherapeutics Inc.
Alzheimer Disease
Study of Intracerebroventricular Injections of Autologous Adipose-Derived Stem Cells (RB-ADSCs) in Participants With Mild-Moderate Alzheimer's Disease
The goal of this Phase 2 clinical trial is to learn if repeated dosing of RB-ADSC (an investigational autologous cell product obtained from participant's own adipose tissue) enhances the positive preliminary results seen in Phase…
- Trial name
- NCT07205601
- Testing
- RB-ADSC
- Volunteers
- 115 people
- Sponsor
- Regeneration Biomedical, Inc.
Anal Fistula
Clinical Trial to Evaluate the Efficacy and Safety of Stem Cells
Efficacy of treatment of perianal fistula with mesenchymal stem cells and surgery
- Trial name
- FISPAC (NCT01803347)
- Testing
- ◦Drug: ASCs. + fibrin glue, fibrin glue
- Where
- 5 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Critical Limb Ischemia
Safety and Effect of Adipose Tissue Derived Mesenchymal Stem Cells Implantation in Patients With Critical Limb Ischemia
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with critical limb ischemia
- Trial name
- NCT01663376
- Testing
- Autologous Adipose Tissue derived MSCs Transplantation
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- R-Bio