Clinical trials: Adipose Tissue-derived Stem Cell
Degenerative Arthritis
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Transplantation in Patient With Degenerative Arthritis
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with degenerative arthritis.
- Trial name
- NCT01300598
- Testing
- Autologous Adipose Tissue derived MSCs Transplantation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- R-Bio
Spinal Cord Injuries, Paralysis
Adipose Stem Cells for Traumatic Spinal Cord Injury
The purpose of this study is to determine if mesenchymal stem cells (MSC) derived from the fat tissue can be safely administered into the cerebrospinal fluid (CSF) of patients with spinal cord injury.
- Trial name
- CELLTOP (NCT03308565)
- Testing
- Autologous, Adipose derived Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mohamad Bydon
Trophic Ulcer
Treatment of Patients With Trophic Ulcers Using Mesenchymal Stem Cells
Treatment of patients with trophic ulcers using injection of autologous adipose-derived mesenchymal stem cells around and inside the wound
- Trial name
- NCT04457037
- Testing
- Autologous adipose-derived mesenchymal stem cells
- Where
- Belarus
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Stress Urinary Incontinence
Effectiveness and Safety of Cell-Assisted Lipotransfer for the Treatment of Stress Urinary Incontinence
Autologous washed and homogenized fat micrograft harvested from the patient's front abdominal wall enriched with adipose-derived regenerative cells (ADRC) derived by enzyme-treatment of a portion of the harvested fat.
- Trial name
- NCT01850342
- Testing
- Periurethral injection of fat micrograft enriched with ADRC
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Idiopathic Parkinson's Disease
Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's Disease
Primary Objective: To assess the safety profile of autologous MitoCell administered to subjects with idiopathic Parkinson's disease (PD) Secondary Objective: To explore the efficacy and safety of MitoCell given as the recommended…
- Trial name
- NCT05094011
- Testing
- Aadipose-Derived Mesenchymal Stem Cells
- Volunteers
- 9 people
- Sponsor
- Taiwan Mitochondrion Applied Technology Co., Ltd.
Liver Transplant; Complications, Liver Diseases
Adipose-Derived Mesenchymal Stem Cell for Preventing Biliary Complications
The purpose of this study is to assess the safety of autologous Adipose-Derived Mesenchymal Stem Cell for use in End-Stage Liver Disease patients undergoing the creation of a duct-to-duct anastomosis during Living Donor Liver…
- Trial name
- NCT06649864
- Testing
- Autologous adipose derived mesenchymal stromal cells (AMSC)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Azoospermia, Oligozoospermia
Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility
Severe Oligospermia (oligozoospermia) refer to semen with a low concentration of sperm and is a common finding in male infertility.
- Trial name
- NCT03762967
- Testing
- Lipoaspiration and SVF introduction., Standard therapy.
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Diabetes Mellitus, Type 2
Autologous SVF Therapy for Type 2 Diabetes
This prospective clinical study aims to evaluate the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF), enriched with mesenchymal stem cells (ADSCs), for the treatment of Type 2 Diabetes Mellitus…
- Trial name
- LASER-DM2 Tria (NCT07487467)
- Testing
- Autologous Adipose-Derived Stromal Vascular Fraction (SVF)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Kaiser Clinic and Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis
This is a phase 2 open-label, 6 arms (1 study group and 1 control group for each joint category), randomized control group clinical study with 300 subjects diagnosed with osteoarthritis of knees (n=100), hips (n=100) and…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Shoulder
- Trial name
- AdMSCs (NCT04448106)
- Testing
- Celltex- AdMSCs
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Celltex Therapeutics Corporation
Diabetic Foot
Autologous Micro-fragmented Adipose Tissue in the Treatment of Minor Amputations of Diabetic Foot
This is a randomized controlled monocentric study on 114 diabetic patients with the aim of evaluating the efficacy of the lipofilling with Lipogems® system in diabetic patients that are candidates for a minor amputation in the…
- Trial name
- NCT03276312
- Testing
- Lipogems
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- University of Modena and Reggio Emilia
Keratopathy
Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)
Evaluate the use of the autologous ASC for the treatment of bilateral limbic associated keratopathy
- Trial name
- HULPOFT (NCT01808378)
- Testing
- Expanded adipose-derived stem cells
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Corona Virus Infection, Covid19
Clinical Study for Subjects With COVID-19 Using Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells
This is an interventional new drug clinical trial for a Phase 2 randomized, double-blind, and placebo control study using intravenous injection of allogeneic adipose stem cells (Celltex AdMSCs) for subjects with severe COVID-19.
- Trial name
- AdMSCs (NCT05017298)
- Testing
- Allogeneic adipose-derived stem cells
- Volunteers
- 30 people
- Sponsor
- Celltex Therapeutics Corporation
Rectovaginal Fistula
Autologous Adipose-derived Regenerative Cells Injection for Treatment of Radiation-induced Rectovaginal Fistula
A new strategy for treatment of late radiation damage is to develop methods aimed at stimulating the regenerative capabilities of irradiated tissues.
- Trial name
- NCT03643614
- Testing
- Injection of autologous regenerative cells of adipose tissue
- Where
- Russia
- Volunteers
- 16 people
- Sponsor
- South Ural State Medical University
Combination of SVF and PRP for Androgenetic Alopecia
Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia
Androgenetic alopecia (AGA) is a common form of hair loss in both men and women, characterized by progressive patterned loss of hair from the scalp.
- Trial name
- AGA (NCT02865421)
- Testing
- stem cells, platelet rich plasma
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Spinocerebellar Ataxias
Stemchymal® for Polyglutamine Spinocerebellar Ataxia
The purpose of the clinical trial is to study the therapeutic efficacy and safety of Stemchymal® infusions for polyglutamine spinocerebellar ataxia treatment by a randomized, double-blind, placebo-controlled study design.
- Trial name
- NCT06397274
- Testing
- Stemchymal
- Volunteers
- 20 people
- Sponsor
- Steminent US, Inc.
Lateral Epicondylitis
Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC)
The aim of this study is to evaluate the efficacy and safety of intra-tendon injection of allogeneic adipose-derived mesenchymal stem cells (Allo-ASC) in intractable common extensor tendinosis patients in comparison with a…
- Trial name
- NCT03449082
- Testing
- High concentration of Allo-ASC, Low concentration of Allo-ASC, Fibrin glue
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Adipogenesis
Small Intestinal Submucosa Scaffold Combined With Adipose-derived Stem Cells to Form an Adipocyte-containing Hypodermis
Human adipose tissues were obtained from five healthy adult women who underwent abdominal liposuction. They were aged 28 to 45 years (mean, 32.15±4.8 years) and had no infectious or endocrine diseases.
- Trial name
- NCT02560350
- Testing
- no intervention
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Moderate to Severe Chronic Kidney Disease
Adipose-derived Stem Cells (ADSCs) for Moderate to Severe Chronic Kidney Disease
1. To assess the safety of allogeneic injection of expanded ADSCs to patients with Moderate to Severe Chronic Kidney Disease 2. To assess the efficacy of allogeneic injection of expanded ADSCs to patients with Moderate to Severe…
- Trial name
- NCT02933827
- Testing
- ELIXCYTE
- Where
- 3 sites in Taiwan
- Volunteers
- 39 people
- Sponsor
- UnicoCell Biomed CO. LTD
Venous Leg Ulcer, Autologous Adipose Stromal Vascular Fraction
Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers
To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with chronic non-healing venous leg ulcers.
- Conditions
- Venous Leg Ulcer, Autologous Adipose Stromal Vascular Fraction, Adipose-Derived Mesenchymal Stem Cells, Mesenchymal Stem Cells
- Trial name
- NCT05165459
- Testing
- Venous leg ulcer treatment with adipous SVF
- Where
- Hungary
- Volunteers
- 10 people
- Sponsor
- Szeged University
Burn
A Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Deep Second-degree Burn Wound
This is a phase I study to evaluate the safety of ALLO-ASC-DFU for the treatment of deep second-degree burn wound patients. ALLO-ASC-DFU is a hydrogel sheet containing allogenic adipose-derived mesenchymal stem cells.
- Trial name
- NCT02394873
- Testing
- ALLO-ASC-DFU
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Anterogen Co., Ltd.