Clinical trials: Adiposity
Healthy Participants, Overweight or Obese Participants
Clinical Trials of IBI3040 in Healthy Participants and Overweight or Obese Participants
Clinical trials of IBI3040 with single-dose administration in healthy participants and multiple-dose administration in overweight or obese participants.
- Trial name
- NCT07765160
- Testing
- SAD: subcutaneous injection in the abdomen, MAD: subcutaneous injection in the abdomen
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Obesity
Treatment of Childhood Obesity in Primary Care
This project will apply the concepts from the Chronic Care Model to the problem of pediatric obesity and proposes: 1) to assess the effectiveness of teaching primary care providers (in diverse practice settings) to use specific…
- Trial name
- NCT00398359
- Testing
- Motivational Interviewing (physicians), Behavior Modification (families)
- Where
- 6 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy, Adult
Understanding Effects of Calcium on the Gut-Bone Axis
The study team is inviting 13 healthy people to complete a study to explore how calcium affects hormones and bones after eating. Participants will be asked to complete two study visits within eight weeks.
- Conditions
- Healthy, Adult, Calcium, Bone Resorption
- Trial name
- NCT06383117
- Testing
- Calcium carbonate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Obesity
Trigona Honey and Intestinal Microbiota Among Obese People
Objective : Nutrition intervention is one of the approaches to deal with obesity. Natural honey with its polyphenol component has an impact on the intestinal microbiota and lipid profile.
- Trial name
- NCT04974450
- Testing
- Trigona honey, control
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH)
A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment
This study aims to evaluate the pharmacokinetic effects of a single dose of HRS-4729 injection in participants with mild, moderate, and severe renal impairment, with 8 participants enrolled in each renal impairment group and 8…
- Conditions
- Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH), Type 2 Diabetes Mellitus
- Trial name
- NCT07807059
- Testing
- HRS-4729
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Overweight and Obesity, Insulin Sensitivity
Does Hyperbaric Oxygen Therapy Lead to a Sustained Increase in Insulin Sensitivity?
In a recent series of studies performed by our group, we have shown that exposure to hyperbaric oxygen (HBOT) leads to an increase in insulin sensitivity in male subjects and that this improvement can be measured in all men, not…
- Trial name
- HOTAIR3 (NCT02136615)
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity
Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRI
Background: It is important for doctors to know how much fat a person has in his or her body. Machines called DXAs measure how much fat mass and fat-free mass a person has.
- Trial name
- NCT02346474
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy, Diabetes Type 2
Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness.
The ASI Non-Invasive Arterial Stiffness Screening Device (ASI Device) is an investigational device under development for the non-invasive assessment of arterial stiffness.
- Conditions
- Healthy, Diabetes Type 2, Obesity, Coronary Artery Disease
- Trial name
- ASI-2012 (NCT01722474)
- Testing
- ASI Device
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity
The Effect of 5-Hydroxytryptophan (5-HTP) on Satiety
The aim of the study is to show evidence of the efficacy of 5-HTP to induce satiety and to reduce food intake (confirmatory study).
- Trial name
- NCT00328913
- Testing
- 5-hydroxytryptophan (food supplement)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Overweight, Obesity
Nutrition, Exercise, and Technology for Weight Loss
The purpose of this study is to evaluate whether a social support-enhanced, technology-based, behavioral weight control intervention can improve weight loss over existing best practices.
- Trial name
- NCT02731768
- Testing
- Standard, Social support-enhanced, Fitbit Zip
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Airway Ultrasound, Difficult Intubation
Airway Ultrasound Versus Mallampati Score as a Predictor of Difficult Direct Laryngoscopy in Obese Patients
The purpose of this study is to evaluate the ability of pre-operative ultrasound assessment of neck anatomy in predicting difficult laryngoscopy in obese patients undergoing elective surgery requiring tracheal intubation and…
- Conditions
- Airway Ultrasound, Difficult Intubation, Mallampati Score
- Trial name
- NCT06057818
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Body Weight, Obesity
Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity
Sugars have been implicated in the epidemics of overweight and obesity. This view is supported by lower quality evidence from ecological observations, animal models, and select human trials.
- Conditions
- Body Weight, Obesity, Overweight, Adiposity
- Trial name
- NCT02558920
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Obesity, Time Restricted Feeding
Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)
Time restricted feeding (TRF) is a novel type of intermittent calorie restriction diet that involves eating a daily period of 8 hours or less.
- Conditions
- Obesity, Time Restricted Feeding, Weight Loss, Calorie Restriction
- Trial name
- TREATY (NCT03745612)
- Testing
- Time restricted feeding, Continuous Energy Restriction
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Obesity
Effect of a Novel Nutraceutical on Weight Loss and Weight Maintenance in Obese Subjects
The purpose of this 2-stage intervention study is to investigate the effect of a novel nutraceutical (containing tetrahydro iso-alpha acids derived from hops) on weight loss and weight loss maintenance in obese participants.
- Trial name
- NCT01656681
- Testing
- THIAA
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- MetaProteomics LLC
Healthy Volunteers
Effect of Concurrent and Aerobic Exercise on VO2max, Strength, and Body Composition in Overweight and Obese Adults
Concurrent and aerobic physical exercise are recognized strategies for the treatment of overweight and obesity. The interventions of these modalities have been performed with cardiovascular machines or guided execution in their…
- Trial name
- NCT05867498
- Testing
- Concurrent exercise, Aerobic exercise
- Where
- Colombia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Obesity, Adolescent Obesity
Chronotropic Incompetence During Exercise in Obese Adolescents: Clinical Implications and Pathophysiology
A reduction in peak heart rate (HR) and suppressed HR response during exercise is highly prevalent in obese populations. This phenomenon is also known as chronotropic incompetence (CI).
- Trial name
- CICO (NCT03516721)
- Testing
- the prevalence of chronotropic incompetence CI during maximal cardiopulmonary exercise testing, CPET
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Obesity
Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss
The purpose of the trial was to examine the independent effects of equivalent diet- or exercise-induced weight loss on obesity and related cardiovascular health risk factors.
- Trial name
- NCT00664547
- Testing
- Diet Weight Loss, Exercise Weight Loss, Exercise Without Weight Loss
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Overweight, Obesity
Association Between the Menstrual Cycle and Weight Loss
This is a research study to look at the association between weight loss and the menstrual cycle in healthy, overweight, premenopausal women.
- Trial name
- NCT01119976
- Testing
- Reduced calorie diet and exercise plan, Different reduced calorie diet and exercise plan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 2, Insulin Resistance
Interleukin-1 Receptor Antagonist and Insulin Sensitivity
Obesity is characterized by continuous low-grade inflammation. This is an important link between obesity and insulin resistance.
- Trial name
- NCT00928876
- Testing
- Anakinra (Kineret)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Obesity
Extended Evening Fasting: Metabolic Health and Energy Balance
This study will compare metabolic and feeding behaviour responses to 4 days of extended evening fasting vs. a control trial
- Trial name
- NCT04924517
- Testing
- Extended Evening Fasting, Control
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
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