Clinical trials: Adiposity
Overweight, Childhood, Obesity in Children
The Bloom Study - a Safe and Healthy Start in Life
The aim of the Bloom Study is to promote healthy weight development among infants through a home-based health promoting intervention implemented in the Danish setting of community health nurses.
- Trial name
- NCT06705400
- Testing
- Multi-behavioural
- Where
- Denmark
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Pediatric Obesity, Impact of Parent Intervention on Adolescent Weight Loss
Study of a Structured Parent Intervention on Adolescent Weight Loss Modification Program.
The study will enroll 110 overweight and obese adolescents ages 11-16 in a lifestyle modification program focusing on dietary modification and exercise.
- Trial name
- NCT02086851
- Testing
- Lifestyle Intervention, Parent Motivational Interviewing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity, Type 2 Diabetes
Video Games for Obesity and Diabetes Prevention-Diab & Nano
With the increasing rates of child obesity and diabetes, innovative programs are needed that capture children's attention and permit behavior change messages to get through.
- Trial name
- G4H-DiabNano (NCT01846377)
- Testing
- G4H-Diab-Nano
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Nutrition, Mastication
Mastication and Energy Expenditure in Normal Weight and Obese People
The objective of the study is to analyze the specific role of physical properties of food and mastication in the cephalic phase reflex of thermogenesis, and the involvement of the autonomic nervous system in the implementation of…
- Trial name
- MASTICAL (NCT04050930)
- Testing
- Mastication
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Inflammation
The Effects Grapes on Health Indices
The investigators hope to learn about the effects of whole grapes, in the form of freeze-dried grape powder, on markers of health.
- Conditions
- Obesity, Inflammation, Cardiovascular Disease, Oxidative Stress
- Trial name
- NCT01674231
- Testing
- Grape in the form of freeze-dried whole grape powder
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Type 1 Diabetes
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT05794581
- Testing
- CT-868, Victoza
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Obesity, Adult
Efficacy of Mindful Tai Chi on Obese or Overweight Adults: A Randomized Controlled Clinical Trial
Background: New weight-loss intervention programs are being studied to determine their effectiveness in helping overweight and obese individuals reach a healthy weight.
- Conditions
- Obesity, Adult, Healthy
- Trial name
- NCT01264029
- Testing
- Mindful Tai Chi Intervention, Mindfulness Meditation, Mall Walking
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Metabolic Syndrome X, Weight Loss
Effect of Two Diets With Different Content of Protein on Weight Loss in Adults With Metabolic Syndrome
Randomised clinical trial with a 6-month follow-up in Mexican adult men and women (20-65 years) with Metabolic Syndrome (MS). The sample size was calculated using a formula that compares two means, an alpha of 0.05 and a power of…
- Trial name
- DPMS (NCT02278757)
- Testing
- High protein diet, Low protein diet
- Where
- Mexico
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Mexican National Institute of Public Health
Obesity, Childhood
Cow Milk Fat Obesity pRevention Trial
Cow's milk is a dietary staple for children in North America. Though clinical guidelines suggest children transition from whole (3.25% fat) milk to reduced (1%) fat milk at age 2 years, recent epidemiological evidence supports a…
- Trial name
- CoMFORT (NCT03914807)
- Testing
- Whole (3.25%) cow's milk recommendation, Reduced (1%) fat milk
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Doppler Measurement of Uterine Artery
Obesity Doppler in Term Pregnancy
Maternal obesity is an epidemic in the developed world like Egypt. There are many pregnancy-associated complications including pre-eclampsia, gestational diabetes, and increased rates of septic wound after cesarean delivery.
- Trial name
- NCT06644911
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity
Adapted Physical Activity Study
An uncontrolled, non-randomized, open-plan, multi-centre study of treatment and therapeutic education in endocrinology-diabetes-Nutrition that seeks to assess the interest of an adapted physical activity educator for the…
- Trial name
- APA (NCT03337412)
- Testing
- Adapted physical activity
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Overweight or Obesity
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy Subjects
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-4729 injection in healthy subjects.
- Trial name
- NCT06762600
- Testing
- HRS-4729 injection, HRS9531 injection, Acetaminophen
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
NAFLD
Resolution of Liver Fat in Non-alcoholic Fatty Liver Disease
The major adverse health consequences of obesity occur only when non-alcoholic fatty liver disease (NAFLD) also develops. NAFLD is characterized by abnormal hepatic accumulation of triglycerides and other lipids.
- Trial name
- NCT02558530
- Testing
- Low carbohydrate diet
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Obesity, Type 2 Diabetes Mellitus
Effect of Pre-meal Serving of Dairy and Dairy Alternatives on Post-meal Satiety and Glycaemia in Healthy Young Adults
Regular consumption of dairy products is found to negatively associated with metabolic diseases and improve body composition in long term studies and has positive effect on acute glycemia control and satiety.
- Trial name
- NCT04600128
- Testing
- Dairy-based greek yogurt, Dairy-based cheddar cheese, Plant-based yogurt
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Insulin Resistance
A Study of the Safety, Tolerance and Assessment of HE3286 on Insulin Sensitivity and Hepatic Glucose Production
The objectives of this study are to evaluate the safety and tolerance of 20 mg (10 mg BID) of HE3286 when administered orally over 28 days to obese insulin-resistant adult subjects and, to assess the activity of HE3286 on insulin…
- Trial name
- NCT00991107
- Testing
- HE3286
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Harbor Therapeutics
Sarcopenic Obesity, Sarcopenia
Evaluation Of DNA Methylation Pattern In Healthy, Sarcopenic, Obese And Sarcopenic Obese Older Women: A Cross-Sectional Study
INTRODUCTION: Sarcopenic obesity (SO), a functional and clinical condition, is characterized by the coexistence of obesity, marked by excess fat mass and sarcopenia, characterized by reduced strength and muscle mass.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity, Epigenesis, Genetic
- Trial name
- NCT06618430
- Testing
- None (Observational Study)
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity
Clinic, Family & Community Intervention for Children With Overweight and Obesity (Stanford GOALS)
Stanford GOALS is a large-scale, community-based randomized controlled trial of an innovative, interdisciplinary, multi-component, multi-level, multi-setting (MMM) approach to treating overweight and obese children.
- Trial name
- NCT01642836
- Testing
- MMM, Health and Nutrition Education
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy, Obesity
Validation of the Quark RMR Calorimeter (Cosmed) Versus Deltatrac II (GE Health Care Clinical Systems)
Measurement of energy expenditure at rest (12 hours fasting) and in dynamic phase after a meal (600kcal) to compare the results of the two calorimeters in standardized conditions for the validation of quark RMR versus Deltatrac II
- Trial name
- Protocol Quark (NCT00848471)
- Testing
- Quark RMR, Deltatrac II
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy Subjects, Obesity
A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects
This is a single-center, randomized, double-blind, placebo-controlled, escalating single-dose and multiple-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HEC88473 injection in healthy…
- Conditions
- Healthy Subjects, Obesity, T2DM (Type 2 Diabetes Mellitus)
- Trial name
- NCT05943886
- Testing
- HEC88473 injection
- Where
- China
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Dongguan HEC Biopharmaceutical R&D Co., Ltd.
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