Clinical trials: Adjustment Impairment
Depression, Anxiety, Visual Impairment
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
The goal of this study is to develop and pilot test a therapeutic strategy combining cognitive behavioral therapy (CBT) with mindfulness practices tailored for individuals adjusting to vision loss.
- Conditions
- Depression, Anxiety, Visual Impairment, Adjustment, Adjustment Disorder With Anxious Mood
- Trial name
- NCT07073521
- Testing
- Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Chicago Lighthouse
Psychosomatic Disorder, Psychological Distress
Feasibility and Benefits of Digital Services During the COVID19 Pandemic
As a result of the pandemic, hygiene and distancing rules must be followed in Health care/ rehabilitation clinics to ensure the safety of patients and staff.
- Conditions
- Psychosomatic Disorder, Psychological Distress, Psychological Stress, Psychological Disease
- Trial name
- AnhandCOV19 (NCT04453475)
- Testing
- Training session adressing information and health literacy
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Stroke, Acute
Improving Follow up Care for People After Minor Stroke
The goal of this feasibility study is to ascertain if this follow-up programme of care can feasibly be implemented within a healthcare system with people after minor stroke.
- Trial name
- NCT05897905
- Testing
- Personalised, holistic follow-up appointments underpinned by self determination theory
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Imperial College Healthcare NHS Trust
Healthy Subjects, Renal Impairments
Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients
This is a human pharmacology, single-dose study to investigate the pharmacokinetics of orally administered Levetiracetam (LEV) in Japanese subjects with normal renal function and in Japanese subjects with various degrees of…
- Trial name
- NCT01491113
- Testing
- Levetiracetam 250 mg, Levetiracetam 500 mg
- Where
- 2 sites in Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
Emotional Distress, Functional Impairment
Evaluation of Three School-based Mental Health Preventive Interventions in France
To meet adolescents' needs regarding mental health vulnerability, this study aims to propose and evaluate three original school-based preventive interventions delivered to French 13y-adolescents, with respect to their effects on…
- Conditions
- Emotional Distress, Functional Impairment, Psychosocial Problem, Wellbeing
- Trial name
- NCT06059092
- Testing
- Adapt Module, Engage Module, Interact Module
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nimes
Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment and Psychopathology
Mild Cognitive Impairment (MCI) is a condition characterized by cognitive deterioration greater than what is expected from normal aging, representing an important risk factor for the development of dementia.
- Trial name
- MIND (NCT07358962)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Schizophrenia
Neural Correlates of Social Touch and Interoceptive Perception As Potential Biomarker for Impaired Social Functioning
Recent studies have shown that certain biomarkers of schizophrenia could help to better assess the individual course of the disease and thus, contribute to more personalized treatment options.
- Trial name
- SPIRIT (NCT04968223)
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Oldenburg
Hemodialysis Complication, Stress Disorders, Post-Traumatic
The Effect of Roy Adaptation-Based Nursing Intervention
Abstract Objective: The research was conducted to determine the effect of the nursing intervention, which was given to patients according to the Roy Adaptation Model, on patients' stress, psychosocial adjustment, and self-care…
- Conditions
- Hemodialysis Complication, Stress Disorders, Post-Traumatic, Psychosocial Impairment, Self Neglect
- Trial name
- NCT05568342
- Testing
- The Effect of Roy Adaptation-Based Nursing Intervention on Stress, Psychosocial Adjustment and Self-Care Power in Hemodialysis Patients: A Randomized Controlled Experimental Study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep Islam Science and Technology University
Renal Failure, Impaired Renal Function
Linezolid Pharmacokinetics In Patients With Impaired Renal Function (PPT6)
Renal failure patients were treated with linezolid (LZD) for proven or suspected infections by multiresistant Gram-positive cocci.
- Trial name
- LZDPPT6 (NCT02087566)
- Testing
- 600 mg linezolid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Neoplasms
Impaired Immunity in Patients With Cancer: Influence of Cancer Stage, Chemotherapy, and Cytomegalovirus Infection
According to a survey from Department of Health in 2004, cancer has been the leading cause of death in the Taiwan area. In 2004, people died of cancer, accounting for 27.2 percent of all deaths.
- Trial name
- NCT00521287
- Testing
- Immune profiling and DC vaccine
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Hearing Loss, Stress
Clinical Trial of the "Living Well With Hearing Loss Workshop"
This study evaluates whether a 2 hour group session, "The Living Well with Hearing Loss Workshop," can successfully teach hard of hearing people how to best use hearing aids and a variety of personal skills to compensate for the…
- Trial name
- NCT00323427
- Testing
- The Living Well with Hearing Loss Workshop, hearing aid services
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- US Department of Veterans Affairs
Renal Insufficiency, Tenofovir
TDF Dose Adjustment VS. Switching to TAF in TDF-experienced CHB Patients With Renal Impairment
Tenofovir is a nucleotide analog drug that works against both Human immunodeficiency virus (HIV) and HBV. TDF and TAF are prodrug of Tenofovir.
- Trial name
- NCT04391608
- Testing
- Switching to Tenofovir Alafenamide
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Parkinson Disease(PD)
Gait Initiation Difficulty and Anticipatory Postural Adjustment (APA) Impairment in People With PD - Evaluation and Training
Gait initiation (GI) difficulty is common in people with Parkinson's disease (PD). Studies showed that the GI difficulty was related to impaired anticipatory postural adjustments (APA).
- Trial name
- NCT02656355
- Testing
- Weight shift training and APA feedback, Weight shift training without APA feedback
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Stroke, Ischemic, Transient Ischemic Attack
Trajectories of Post-stroke Multidimensional Health
Stroke is thought to cause disability immediately after stroke followed by a 3-to-6-month recovery period, after which disability levels are supposed to stabilize unless recurrent events occur.
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Adaptation, Psychological, Mental Health Impairment
- Trial name
- NeuroAdapt (NCT04704635)
- Where
- Germany
- Volunteers
- 330 people
- Sponsor
- University Medicine Greifswald
Adjustment Disorders, Posttraumatic Stress Disorder
The Trauma of Betrayal: Treating Adjustment Disorder With Reconsolidation Blockade Under Propranolol
Attachment injuries are events occurring within couple relationships that involve betrayal or abandonment by a significant other during times of need (e.g., infidelity).
- Conditions
- Adjustment Disorders, Posttraumatic Stress Disorder, Trauma and Stressor Related Disorders
- Trial name
- NCT03151681
- Testing
- Propranolol Pill
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Douglas Mental Health University Institute
Adjustment Impairment, Accident
SelFIT: Internet-based Treatment for Adjustment Problems After an Accident
In this study, people who suffer from adjustment problems after having experienced an accident will be randomized to one of two study groups.
- Conditions
- Adjustment Impairment, Accident, Adjustment Disorders, Mental Disorder
- Trial name
- SelFIT (NCT03785912)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University of Bern
COVID-19, Immunosuppression
Impact of Immunosuppression Adjustment on COVID-19 Vaccination Response in Kidney Transplant Recipients
Immunocompromised individuals, such as solid organ transplant (SOT) recipients are at high risk of COVID-19 associated complications and mortality.
- Conditions
- COVID-19, Immunosuppression, Vaccine Response Impaired
- Trial name
- ADIVKT (NCT05060991)
- Testing
- Reduction in antimetabolite immunosuppression
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, Davis
Long-COVID, Post-COVID
ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19
Post-/long-COVID occurs in patients with severe, moderate, and even mild courses. The symptomatology is multi-layered and complex.
- Conditions
- Long-COVID, Post-COVID, Psychosomatic Disorder, Psychological Distress
- Trial name
- ASAP (NCT05238415)
- Testing
- Psychological and Physiological Assessments
- Where
- Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Sonia Lippke
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population
The goal of this observational study is to evaluate the functionality and usability of Indivi mobile application-based cognitive activities in people with mild cognitive impairment/mild Alzheimer's disease (PwMCI/AD) and healthy…
- Trial name
- ADAPT-MCI-01 (NCT07174869)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Indivi AG