Clinical trials: Adolescent Depression, open to volunteers
Race-related Stress, Depression, Anxiety
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black…
- Conditions
- Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
- Trial name
- ACT for SCD (NCT05685368)
- Testing
- ACT for SCD
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Hospital Los Angeles
Mental Health, Depression and/or Anxiety in the Mild-to-moderate Range
Effect of a Programme Including an AI-enhanced Mobile Application on the Mental Well- Being of Young Adolescents in Hong Kong
Study Aim and Methods (≈250 words) It aims to evaluate the effectiveness, user perceptions, and applicability of the e-CAMP intervention in improving mental well-being and reducing depressive symptoms among adolescents aged 11-15…
- Trial name
- AI-eCAMP_RCT (NCT07704996)
- Testing
- Control Group :health talk and usual care by school, mobile app group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tung Wah College
Depression, Unipolar
Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness
This study examines the efficacy of bright light therapy as a treatment for adolescents diagnosed with unipolar non-seasonal depression who exhibit an evening chronotype.
- Trial name
- NCT06973759
- Testing
- Bright light therapy, Dim red light
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Depression in Adolescence, Delayed Sleep Phase
Better Sleep Study
The overall aim of this proposal is a confirmatory efficacy trial sufficiently powered and designed to test the hypothesis that improving the relationship between biological circadian timing and waketime, a novel modifiable…
- Trial name
- NCT06139861
- Testing
- TranS-C, Psychoeducation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Hospital Los Angeles
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Anxiety and Depression
Pharmacogenetic-Guided Antidepressant Prescribing in Adolescents With Anxiety and Depression
This is a parallel arm randomized (1:1) controlled trial. Adolescents aged 12-17 years (n=228) who are starting or changing a selective serotonin reuptake inhibitor (SSRI) for depression and/or anxiety will be randomly allocated…
- Trial name
- PGx-GAP (NCT06853587)
- Testing
- Pharmacogenetic-guided dosing, Current prescribing guidelines/recommendations
- Where
- Canada
- Volunteers
- 228 people
- Sponsor
- University of Calgary
Depression in Adolescence, Rumination
Mindfulness-Based fMRI Neurofeedback for Depression
In the United States, adolescents experience alarmingly high rates of major depression, and gold-standard treatments are only effective for approximately half of patients.
- Trial name
- mbNF (NCT05617495)
- Testing
- Mindfulness + fMRI Neurofeedback
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Columbia University
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
Anxiety Depression
Physical Activity Based Treatment for Youth With Depression and Anxiety
The Confident, Active, and Happy Youth (CAHY) project aims to address the significant functional impairments experienced by youths with symptoms of depression and anxiety, focusing on physical activity (PA) and social…
- Trial name
- NCT07304219
- Testing
- Confident, Active and Happy youth (CAHY)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Anxiety Disorders, Depressive Disorder
Psychopathology in Adolescence
This observational study aims to evaluate the effectiveness of two different psychotherapy approaches-Cognitive Behavioral Therapy (CBT) and Brief Strategic Therapy (BST)-in treating adolescents with psychological disorders.
- Conditions
- Anxiety Disorders, Depressive Disorder, Obsessive-Compulsive Disorder, Mental Health
- Trial name
- NCT07259109
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Depression
Dance-movement Therapy in the Treatment of Adolescent Depression
The aim of this research is to measure the effectiveness of Dance movement therapy in the treatment of adolescent depression.
- Trial name
- DMT (NCT07293806)
- Testing
- Dance movement therapy
- Where
- 2 sites in Finland
- Volunteers
- 140 people
- Sponsor
- Helsinki University Central Hospital
Mental Health Issue, Insomnia
Promoting Teenage Sleep for Improved Mental Health and School Performance
The overall aim of this project is to evaluate the effectiveness of two school-based programs that have the potential to promote adolescent sleep and prevent future depressive symptoms.
- Conditions
- Mental Health Issue, Insomnia, Depression, Anxiety
- Trial name
- TeenSleep (NCT06306092)
- Testing
- Sleep on Schedule, Technology restriction
- Where
- Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Kristianstad University
Depression
CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth
Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities…
- Trial name
- NCT05456035
- Testing
- Cognitive behavioral therapy plus social cognitive training (CBTSCT)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Vanderbilt University
Mental Health Issue, Depression
Just-in-Time Training for Youth Mentors
This study will evaluate the usability, feasibility, and acceptability of a novel multi-level Just-In-Time Training (JITT) implementation strategy (JITT-EBP) that aims to equip mentors and mentor supervisors to implement…
- Conditions
- Mental Health Issue, Depression, Anxiety
- Trial name
- NCT07129070
- Testing
- Interpersonal Psychotherapy-Adolescent Skills Training via Just-In-Time Training (JITT) implementation strategy, Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) implemented via usual training
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
ADHD
Omega-3 Fatty Acids, Inflammation, Gut Microbiota in Youth With Depression
This is a 12 week double blind RCT aimed to investigate the role of omega-3 fatty acids in patients with major depressive disorder
- Trial name
- OMIMYDep (NCT07363551)
- Testing
- Omega-3 fatty acids
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Major Depression
Interpersonal Psychotherapy for Adolescents and Young Adults
The purpose of the project is to study the effectiveness of Interpersonal Psychotherapy (IPT) for adolescents with depression. Specific aims are to analyze the effects, change mechanisms, predictors, and implementation of IPT for…
- Trial name
- NCT05575960
- Testing
- Interpersonal Psychotherapy for Adolescents (IPT-A)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linnaeus University
Depression
Well-being Training for Adolescent Depressive Symptoms (TeenWell Study)
This study is being done to see if the Healthy Minds Program app helps adolescents with elevated depressive symptoms. Up to 200 participants will be on study for 20 weeks.
- Trial name
- NCT06626425
- Testing
- Healthy Minds Program App, Hydro Coach App
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Wisconsin, Madison
Subclinical Depressive Symptoms
Preventing Depression of Chinese American Adolescents by RRE
The goal of this clinical trial is to test if a culturally sensitive mobile health application (Relax, Reflect, Empower-RRE) is feasible and effective in promoting psychological wellbeing and reducing depressive symptoms among…
- Trial name
- NCT05921201
- Testing
- Relax, Reflect, and Empower mobile application
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Suicide, Suicidal Ideation
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care
The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use…
- Trial name
- NCT05869552
- Testing
- STAT-PC, YST-III
- Where
- 3 sites in United States
- Volunteers
- 1,485 people
- Sponsor
- Elizabeth Arnold
Major Depressive Disorder (MDD), Thiamine
Oral Thiamine (Vitamin B1) for Depression in Children and Adolescents
The goal of this study is to examine the effectiveness of thiamine in reducing depressive symptoms in children and adolescents. The investigators hypothesize that thiamine administration will alleviate depressive symptoms in…
- Conditions
- Major Depressive Disorder (MDD), Thiamine, Vitamin B1, Thiamine Diphosphate (TDP)
- Trial name
- B1Ped (NCT07793071)
- Testing
- thiamine hydrochloride 100 mg
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital