Clinical trials: Adolescent Pregnancy
Pregnancy in Adolescence
Evaluation of the Talking Matters Teen Pregnancy Prevention Program
A culturally tailored program that creates a safe, open space to increase knowledge, self-efficacy, skills, and comfort related to sexual and reproductive health, including HIV/STI and teen pregnancy prevention, mental health…
- Trial name
- NCT04970485
- Testing
- Talking Matters
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Public Health Management Corporation
Pregnancy
Medical Abortion Via Telemedicine for Women and Adolescents in Moldova
This study evaluates the safety, feasibility, and acceptability of a novel medical abortion via telemedicine service in the Republic of Moldova.
- Trial name
- NCT04316325
- Testing
- Medical abortion
- Where
- Moldova
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- Reproductive Health Training Center of the Republic of Moldova
Feasibility, Acceptability of Health Care
Introduction of Preconception Care Through Public Health System for Improving MNCH&FP
The goal of this study is to test the feasibility and acceptability of introducing preconception care into the public health system targeting newlywed couples in increasing the uptake of maternal, neonatal health, and family…
- Trial name
- MNCH&FP (NCT06175520)
- Testing
- Preconception care (PCC)
- Where
- Bangladesh
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Neonate, Maternal Transmission
Phase 3 Maternal Safety & Immunogenicity Trial of MVA-BN® in DRC
This Phase 3 open-label study aims to assess the safety and immune response of the MVA-BN mpox vaccine when administered subcutaneously to pregnant and postpartum women in the Democratic Republic of the Congo (DRC), a population…
- Conditions
- Neonate, Maternal Transmission, Mpox, Vaccination
- Trial name
- PregInPoxVac (NCT06844500)
- Testing
- MVA-BN standard regimen, MVA-BN standard regimen (Administered as PEP)
- Where
- Democratic Republic of the Congo
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Jean-Pierre Van geertruyden
Contraception
Maintaining Intrauterine Devices (IUDs) in Teens (MINT): A Randomization Trial
This is a pilot study to determine the feasibility for a randomized controlled trial of two forms of intrauterine contraception: the Levonorgestrel intrauterine system (LNG-IUS) and the Copper T 380A.
- Trial name
- MINT (NCT00653159)
- Testing
- Levonorgestrel-releasing intrauterine device (LNG-IUS), Copper T380A intrauterine device (CuT380A)
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)
This single-center, prospective, observational, cross-sectional mechanistic pilot study will evaluate whether polycystic ovary syndrome (PCOS) contributes to hepatic steatosis in adolescent girls independently of adiposity.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Hyperandrogenism
- Trial name
- COMPASSpedPCOS (NCT07731373)
- Testing
- Extended Serum Biomarker and Hormonal Panel, Liver Elastography with Controlled Attenuation Parameter, Targeted Genotyping of PNPLA3 rs738409 and HSD17B13 rs72613567
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Cervical Cancers, Vulvar Cancer
A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002)
This study will evaluate the immunogenicity and tolerability of V503 (a multivalent human papillomavirus [HPV] L1 virus-like particle [VLP] vaccine) in preadolescent and adolescent participants between 9 and 15 years old and…
- Conditions
- Cervical Cancers, Vulvar Cancer, Vaginal Cancer, Genital Lesions
- Trial name
- NCT00943722
- Testing
- V503
- Volunteers
- 3,074 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Congenital Adrenal Hyperplasia
Tweens to Teens Project at Penn State
The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development).
- Trial name
- T2T@PSU (NCT01184651)
- Testing
- Questionnaires/Interviews
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Penn State University
Teenage Pregnancy
Executive Functions and Emotional Intelligence in Pregnant Adolescents
Teenage pregnancy is a major global public health issue and is associated with a range of psychosocial, emotional, and developmental challenges.
- Trial name
- EFAEIPA (NCT07492082)
- Testing
- Psychological intervention program in executive functions and emotional intelligence
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
HIV Infections, Pregnancy Related
Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ
"SKILLZ," is a mixed methods evaluation of the Grassroots Soccer (GRS) SKILLZ Package based in Lusaka, Zambia. The package is made up of three football-based programs: (1) SKILLZ-Girl - implemented in schools as part of a 10-week…
- Conditions
- HIV Infections, Pregnancy Related, STI, Mental Health Wellness 1
- Trial name
- SKILLZ (NCT04429061)
- Testing
- SKILLZ-Girl curriculum
- Where
- Zambia
- Volunteers
- 2,153 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Adolescent Development, Pregnancy Related
COMPARISON OF OBSTETRIC AND NEONATAL OUTCOMES OF ADOLESCENT PREGNANCİES
ABSTRACT Adolescent pregnancy rates are gradually increasing in the recent decades. As a reason of war nutritional difficulties, language differences and difficulty in applying to the health institution causes lack of prenatal…
- Trial name
- NCT04546204
- Testing
- vaginal delivery
- Where
- Turkey (Türkiye)
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Alkü Alanya Education and Research Hospital
Teen Pregnancy
Evaluation of My Future Self, an New Teen Pregnancy Prevention Group Intervention for Youth in Non-traditional Settings
Children's Hospital Los Angeles and ETR will implement and test the effectiveness of a pregnancy prevention intervention, My Future Self, targeting youth ages 16-19 in Los Angeles and San Diego Counties who, for a variety of…
- Trial name
- NCT05796687
- Testing
- My Future Self
- Where
- United States
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Sexual Risk Behavior, Sexually Transmitted Infections
Optimizing the Floreciendo Sexual and Reproductive Health Workshop for Latina Teens and Female Caregivers: A Pilot
Floreciendo is a sexual and reproductive health workshop for Latina teens (ages 14-18 years) and their female caregivers (e.g., mothers, sisters, grandmothers).
- Conditions
- Sexual Risk Behavior, Sexually Transmitted Infections, Unplanned Pregnancy
- Trial name
- Floreciendo (NCT06223165)
- Testing
- Floreciendo (Foundations, Condoms & Contraception, Family Strengthening, and Gender & Relationships), Floreciendo (Foundations, Condoms & Contraception, and Family Strengthening), Floreciendo (Foundations, Condoms & Contraception, Gender & Relationships)
- Where
- 4 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Diabetes, Gestational, Obesity
Maternal GDM in Hispanic Youth: Risk for Obesity
Our studies are aimed at examining effects of intrauterine exposure to GDM on metabolic risks in Hispanic children. Our primary hypothesis predicts that intrauterine exposure to GDM will be associated with one or more of three…
- Conditions
- Diabetes, Gestational, Obesity, Insulin Resistance, Insulin Secretion
- Trial name
- NCT02668601
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Birth Weight, Miscarriage
Micronutrient Supplementation Before and During 1st Pregnancy to Improve Birth Outcomes (JiVitA-5)
The purpose of this cluster-randomized trial is to evaluate the efficacy of daily, multiple micronutrient (MM) supplement versus identical placebo use among nulligravid, recently married women, starting preconceptionally through…
- Conditions
- Birth Weight, Miscarriage, Small-for-gestational Age, Preterm Birth
- Trial name
- JiVitA-5 (NCT03921177)
- Testing
- Multiple micronutrient supplement
- Where
- Bangladesh
- Volunteers
- 9,859 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
CHLAMYDIA INFECTIONS
Immunopathogenesis of Chlamydia
Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and…
- Trial name
- NCT00607659
- Testing
- No intervention, only observational
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Contraception Behavior
Hormonal Contraceptive Health Education for Adolescent Males
Prospective randomized control trial of an educational electronic application on female hormonal contraception for adolescent males in the pediatric emergency department.
- Trial name
- NCT03400410
- Testing
- Education Arm
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Polycystic Ovary Syndrome, Adolescent Behavior
Adolescent Polycystic Ovary Syndrome on a Low-carbohydrate Diet
The aim of the study was to investigate the changes in the clinical and biochemical parameters of adolescents on a low-carbohydrate diet in relation to their PCOS phenotype in the 3rd trimester.
- Conditions
- Polycystic Ovary Syndrome, Adolescent Behavior, Diet Habit
- Trial name
- PCOS (NCT06429618)
- Testing
- Low carbonhydrate diet
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Pregnancy, Sexually Transmitted Diseases
Louisville Teen Pregnancy Prevention Project
This study is comparing the impact of two teen pregnancy prevention interventions, Reducing the Risk and Love Note with a non-related training on community building to determine which is most effective for which participants in…
- Trial name
- CHAMPS (NCT01411878)
- Testing
- Reducing the Risk, Love Notes
- Where
- 12 sites in United States
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome
Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
Polycystic ovary syndrome (PCOS) is one of the most common disease caused by hormonal imbalance and is also associated with overweight and obesity. It affects 5-10% of adolescent girls and women capable of having children.
- Conditions
- Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
- Trial name
- NCT01840618
- Testing
- Nasal Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine