Clinical trials: Adolescent Substance Abuse
Substance Abuse, Families
Family-Based Drug Services for Young Disaster Victims
This protocol seizes this rare scientific opportunity to test an integrative family based model to address youths' coexisting substance abuse and trauma in the wake of Hurricane Katrina.
- Conditions
- Substance Abuse, Families, Trauma
- Trial name
- Katrina (NCT01859000)
- Testing
- Multidimensional Family Therapy, Group CBT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV, Substance Abuse
Young Women's Health CoOp (Cooperative) in Cape Town
This supplement study is an adaptation of the larger NIH-funded parent study, the Women's Health CoOp+, which tests a combination biobehavioral HIV prevention approach to enhance standard HIV testing practices for alcohol and…
- Trial name
- YWHC (NCT02677025)
- Testing
- Young Women's Health CoOp (YWHC), HIV Counseling/Testing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RTI International
Psychoactive Substances Consumption, Substance-related Disorder
French Study on COgnitive Enhancement and Consumption of Psychoactive Substances Among Youth Students
This descriptive and declarative study will help to find out consumption rates, all psychoactive substances taken together, among 18-25 year olds.
- Conditions
- Psychoactive Substances Consumption, Substance-related Disorder, Off Label-use, Cognitive Enhancement
- Trial name
- ENQUETE-COSYS (NCT02954679)
- Testing
- Online self-administrated and anonymous survey questionnaire
- Where
- France
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adolescent Psychiatry, Antisocial Personality Disorders
Impaired Decision-making in Adolescents
There is clear evidence that aggressive behavior and disruptive behavior disorders (DBD) in middle childhood are associated with an increased risk for substance abuse in adolescence.
- Conditions
- Adolescent Psychiatry, Antisocial Personality Disorders, Substance-Related Disorders
- Trial name
- NCT01253993
- Where
- Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Homeless Youth Study - Stepping Stone 2.0
Housing instability is both a cause and consequence of mental health problems. As such youth experiencing housing instability (e.g., homeless or marginally housed) have higher rates of mental health problems.Because of their…
- Trial name
- NCT03776422
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cannabis Use
A Hybrid Effectiveness-Implementation Trial of a School-Based Teen Marijuana Checkup
A hybrid effectiveness-implementation trial that is designed to assess the effectiveness of an intervention (The Teen Marijuana Check-Up) when delivered in real world settings.
- Trial name
- TMCU5 (NCT03111667)
- Testing
- Teen Marijuana Check Up, Treatment as Usual, Gold Standard Coaching
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV/AIDS and Infections, Drug Abuse
Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention
The study evaluates the preliminary efficacy of an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) to improve human immunodeficiency virus and sexually transmitted infection testing and reduce HIV/STI…
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03368456
- Testing
- S4E, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Study Focuses on Brain Morphology and Cognition in Older Subjects
Cannabis Effects on Brain Morphology in Aging
Marijuana (Cannabis sativa) is the most widely used illicit drug worldwide, with 17.4 million Americans reporting past month use in 2010 and 4.6 million meeting criteria for dependence, underscoring the public health importance…
- Trial name
- CAN (NCT01874886)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol Abuse
Family Based Contingency Management for Adolescent Alcohol Abuse
The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence. Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat…
- Trial name
- NCT00595478
- Testing
- Motivational Enhancement Therapy (MET)/CBT+CM, Motivational Enhancement Therapy (MET)/CBT
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid Related Disorders
Computer-based Prescription Opioid Abuse Prevention for Adolescents
The investigators are developing an interactive, web-based program for youth ages 12-17 focused on the prevention of prescription opioid abuse because to the investigators knowledge, no science-based, interactive program focused…
- Trial name
- NCT02737696
- Testing
- Web-based prescription opioid prevention for adolescents, JustThinkTwice.gov website (DEA)
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Substance Use
Adaptation Processes in School-Based Substance Abuse Programs
The goals of this study are to develop a middle school substance use prevention curriculum for underserved rural youth and evaluate its efficacy compared to the existing, multicultural curriculum.
- Trial name
- NCT01755533
- Testing
- Rural curriculum, Classic curriculum
- Where
- United States
- Volunteers
- 2,827 people, healthy volunteers welcome
- Sponsor
- Penn State University
Substance Abuse
Adolescent Involvement in Parental Substance Abuse Treatment
Given the reciprocal nature of parent-child interaction, involvement of the adolescent in their mother's substance abuse treatment plan might be associated with reductions in adult relapse and improvements in child functioning.
- Trial name
- NCT01576393
- Testing
- Home-based Family Therapy, office-based family therapy, WHE
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Substance Abuse
Preventing Drug Abuse Among Sexual Minority Youth
The planned randomized clinical trial will longitudinally test a tailored, web-based drug abuse prevention program with a nationwide sample of 15- to 17-year-old sexual minority youth (youth who identify as gay, lesbian…
- Trial name
- NCT03954535
- Testing
- Free2b
- Where
- United States
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Columbia University
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Alcoholism, Substance Abuse
Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent
ASSIST mini-intervention is applied in an electric form in adolescent outpatients to see if it
- Conditions
- Alcoholism, Substance Abuse, Alcohol Dependence, Alcohol-Related Disorders
- Trial name
- REAL-SMART (NCT06262958)
- Testing
- ASSIST, Treatment as usual
- Where
- Finland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Drug Abuse Prevention
A Web-Based Intervention to Prevent Drug Abuse Among Adolescent Girls
This study is designed to develop and test a gender-specific, web-based drug abuse prevention program. Study participants will be adolescent girls aged 13 and 14 years who will complete all measures online.
- Trial name
- NCT01813123
- Testing
- RealTeen
- Where
- United States
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Youth to Text or Telehealth for Engagement in HIV Care
Youth To Text or Telehealth for Engagement in HIV Care (Y2TEC) is a randomized control pilot to assess the feasibility and acceptability of delivering a targeted problem-solving intervention to youth ages 18-29 living with HIV…
- Conditions
- HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
- Trial name
- Y2TEC (NCT03681145)
- Testing
- Counselor delivered telehealth intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Drug Abuse
Brief Intervention for Drug Abusing Adolescents
The purpose of this clinical trail is to evaluate the efficacy of a brief, cognitive-behavioral therapeutic intervention for adolescents reporting mild or moderate drug abuse (MMDA).
- Trial name
- NCT00350909
- Testing
- brief intervention (cognitive-behavioral therapy)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota