Clinical trials: Adolescent Suicide
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Mental Disorders, Suicide, Attempted
Ideation Trajectories and Suicide Attempts in Adolescents With Psychiatric Disorders in Chile
This project seeks to evaluate the trajectories of suicidal ideation and attempts in adolescent patients with psychiatric disorders in secondary care controls in the Maule region, in relation to clinical factors (depressive…
- Trial name
- NCT04635163
- Testing
- None intervention
- Where
- Chile
- Volunteers
- 388 people
- Sponsor
- Universidad Católica del Maule
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Social Functioning, Emotional Distress
Emerging Technologies and Teen Mental Health
This study will recruit teens who are experiencing subacute suicidal ideation to test the effect of a brief psychoeducational intervention focused on social media use wherein youth learn about active and prosocial use of social…
- Conditions
- Social Functioning, Emotional Distress, Suicidal Ideation
- Trial name
- NCT07527052
- Testing
- Prosociality and Agency in Algorithmic Spaces (PAAS) Module
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Florida International University
Adolescent Behavior, Suicidal Ideation
Navigating Mental Health Treatment for Black Youth
This study looks to conduct a systematic adaptation of Suicidal Teens Accessing Treatment (STAT-ED) for Black youth presenting in the emergency department who have suicide risk.
- Trial name
- NCT05334381
- Testing
- Adapted STAT-ED, Standard Enhanced Treatment As Usual
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Depression, Suicide and Self-harm
Telehealth Behavioral Activation for Teens
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to…
- Conditions
- Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild
- Trial name
- NCT06273995
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Baylor College of Medicine
Suicide, Suicidal Ideation
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care
The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use…
- Trial name
- NCT05869552
- Testing
- STAT-PC, YST-III
- Where
- 3 sites in United States
- Volunteers
- 1,485 people
- Sponsor
- Elizabeth Arnold
Distress; Maternal, Self Efficacy
Integrated Intervention for Caregivers--Pilot RCT
Adolescents who have been hospitalized for suicidal behavior are at risk for engaging in additional suicidal behavior. After hospitalization, parents or guardians are typically asked to be responsible for helping to prevent…
- Conditions
- Distress; Maternal, Self Efficacy, Parenting, Suicide
- Trial name
- NCT03487627
- Testing
- Electronic and Care Support Manager Contact, Enhanced Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Suicide
Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska
This intervention study measures the outcomes of the PC CARES (Promoting Community Conversations about Research to End Suicide) project implemented in remote rural Alaskan villages.
- Trial name
- PC CARES (NCT03661255)
- Testing
- PC CARES
- Where
- United States
- Volunteers
- 1,427 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicidal Behavior, Adolescent
Suicidal Behavior in Adolescents and Executive Functions
Suicide is a major public health concern, particularly among young people. In France, around 400 adolescents die by suicide every year, and suicide attempts are most frequent during adolescence.
- Trial name
- SAFE (NCT07422493)
- Testing
- Neuropsychological Tests and Psychiatric Tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Suicide, Attempted, Suicide Ideation
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps…
- Conditions
- Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
- Trial name
- NCT06151158
- Testing
- Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
- Where
- 6 sites in United States
- Volunteers
- 484 people
- Sponsor
- Johns Hopkins University
Treatment as Usual, Family Navigator
Family Navigator Intervention
This study will develop and examine the feasibility and acceptability of a family navigator protocol while leveraging digital health communication.
- Trial name
- NCT05954585
- Testing
- Treatment as usual, Family Navigator
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Rhode Island Hospital
Suicide, Surveillance
Southwest Hub for American Indian Youth Suicide Prevention Research
1. To use a SMART design to evaluate which of four sequences of New Hope (NH), Elders Resilience (ER) and Case Management (CM) have the greater effects on immediate and longer-term suicidal ideation (primary outcome) and…
- Conditions
- Suicide, Surveillance, Mental Health, Substance Use
- Trial name
- NCT03543865
- Testing
- New Hope (NH), Elders Resilience (ER), Case Management (CM)
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Depression in Adolescence, Suicidal Ideation
Social Media Concerns Related to Emotional Experiences in Naturalistic Settings (SCREENS)
The objective of this study is to advance understanding of the relationships between social media use (SMU) and internalizing symptoms among a diverse sample of depressed and/or suicidal youth.
- Conditions
- Depression in Adolescence, Suicidal Ideation, Social Media Addiction, Mental Health Issue
- Trial name
- SCREENS (NCT07278752)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide, Adolescent Behavior
Wearable Suicidal Early Warning System for Adolescents
This study is prospectively enrolling a cohort of adolescent patients who present to the Emergency Department and an inpatient psychiatric adolescent unit with acute suicidality.
- Trial name
- NCT03030924
- Testing
- Solace
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Bipolar Disorder, Suicidal Ideation
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
This study aims to use a retrospective cohort approach to explore the impact of lithium carbonate on suicide and self-harm related events among adolescents and young adults with bipolar disorder in China.The primary objective of…
- Conditions
- Bipolar Disorder, Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self Injury
- Trial name
- NCT06424613
- Testing
- Lithium Carbonate, Non-lithium medication
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University
Self Harm, Suicidal Ideation
Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents
Suicidal thoughts, suicide attempts, and suicide are increasingly common in adolescence. Current face-to-face prevention approaches are of limited effectiveness, rely on extensive resources, and are at odds with adolescents'…
- Trial name
- NCT05602779
- Testing
- tVNS Program, Phone App Program, tVNS and Phone App Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Notre Dame
Sleep Disturbance, Sleep
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior.
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- NCT06963463
- Testing
- TranS-C, Sleep Feedback
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh