Clinical trials: Adrenergic Beta-Receptor Blockader
Acute Myocardial Infarction (AMI)
HMO Research Network CERT: Acute Myocardial Infarction
The primary goal of this study is to evaluate the effectiveness of direct-to-patient mailings designed to increase patient's adherence to prescribed beta-blockers following an acute myocardial infarction (AMI).
- Trial name
- NCT00211172
- Testing
- Beta-blocker adherence after an AMI
- Where
- 4 sites in United States
- Volunteers
- 836 people
- Sponsor
- Kaiser Permanente
Adrenergic Beta-Receptor Blockader, Troponin Levels
Pilot - Peri-operative Beta Blockade
Perioperative cardiac adverse events [heart injuries caused by general anesthesia and surgical procedures] are a significant public health issue, with more than 60,000 deaths per annum in patients having surgery for non-heart…
- Conditions
- Adrenergic Beta-Receptor Blockader, Troponin Levels, Cardiomyopathy, Post-surgical
- Trial name
- NCT02746575
- Testing
- metoprolol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Marfan Syndrome
Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome
Marfan syndrome is a hereditary connective tissue disorder. Many individuals with this condition die because of the associated heart and blood vessel abnormalities.
- Trial name
- NCT00429364
- Testing
- Losartan Potassium, Atenolol
- Where
- 26 sites in United States, Belgium and 1 more
- Volunteers
- 608 people
- Sponsor
- Carelon Research
Pain Measurement
Evaluation of Propranolol's Effect on Pain and Inflammation.
Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects…
- Trial name
- NCT01094574
- Testing
- Alfentanil, Propranolol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Martin Angst
Hypertension
The Effect of Nebivolol on Insulin Sensitivity
The purpose of this study is to conduct a randomised trial to compare the insulin sensitivity, 24 hour blood pressure profile, and tolerability of nebivolol plus a thiazide-like diuretic versus atenolol plus a thiazide-like…
- Trial name
- NCT00125853
- Testing
- Nebivolol, Atenolol
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Imperial College London
Cardiac Arrest, Sudden Cardiac Death
Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
The purpose of this research study is to evaluate the effectiveness of metoprolol, a "beta blocker," in treating patients in the hospital with a cardiac arrest. It will be given intravenously (given into a vein).
- Conditions
- Cardiac Arrest, Sudden Cardiac Death, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- Shock n Block (NCT00401882)
- Testing
- Epinephrine, Metoprolol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- David Haines, MD
Idiopathic Dilated Cardiomyopathy
Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart
The primary goal of the study is to measure in the intact human heart, the alterations in gene expression over time that are associated with reverse remodeling in response to β-blockade.
- Trial name
- BORG (NCT01798992)
- Testing
- Carvedilol, Metoprolol succinate, Metoprolol succinate + doxazosin
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- University of Colorado, Denver
Pulmonary Disease, Chronic Obstructive
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI
The study is a prospective, observational study of patients admitted to the BLOCK COPD network hospitals with acute AMI and Chronic Obstructive Pulmonary Disease (COPD) to determine the prevalence of COPD in patients admitted to…
- Trial name
- BLOCK2 (NCT04717492)
- Testing
- Observational
- Where
- 24 sites in United States
- Volunteers
- 584 people
- Sponsor
- University of Minnesota
Cervical Cancer
Feasibility - Beta Adrenergic Blockade (BB) in Cervical Cancer (CX)
The goal of this clinical research study is to learn how many patients with advanced, recurrent, incurable cervical cancer will complete questionnaires about symptoms, any anxiety, depression, and/or pain, and the quality of…
- Trial name
- NCT01902966
- Testing
- Propranolol, Diary, Relaxation Audio Recording
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure
Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison
The overall objective of the proposed pilot study is to begin evaluation of two methods for promoting adherence to guidelines for beta-blocker therapy in heart failure.
- Trial name
- NCT01002456
- Testing
- Level 1: (provide site-specifi information), Level 2 (Provide site- and patient-specific information)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- US Department of Veterans Affairs