Clinical trials: Advanced Age
Influenza
Evaluation of the Safety and Immunogenicity of the Influenza Vaccine GSK2186877A in the Elderly
The purpose of this observer-blind clinical trial is to evaluate the safety and immunogenicity of GlaxoSmithKline Biologicals' influenza vaccine GSK2186877A in the elderly. Subjects were previously vaccinated (NCT00529516).
- Trial name
- NCT00772889
- Testing
- Influenza vaccine GSK2186877A, GSK Biologicals' Fluarix™
- Where
- 29 sites in United States, Belgium and 2 more
- Volunteers
- 971 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Elderly
Effect of the Virtual Reality Training in Elderly
The study aims to investigate the efficacy of group-based exercises using virtual reality on activities of daily living in elderly population.
- Trial name
- NCT05703568
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Healthy
Elderly Consumer Survey
This study is a cross-sectional study, aiming to recruit 200 community-dwelling elderly, aged 60 years and above. Recruitments will be made from St. Luke's ElderCare's (SLEC) active aging hubs around Singapore.
- Trial name
- NCT07296978
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Technology
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single and Multiple Doses of AZD1446 to Japanese Subject
The primary aim of this study is to assess the safety and tolerability of AZD1446 following single and multiple ascending doses of an orally administered solution of AZD1446 in healthy young and elderly Japanese subjects.
- Trial name
- NCT01021189
- Testing
- AZD1446
- Where
- Japan
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Dementia, Cognitive Function
B-vitamins and Omega-3 Fatty Acids and Biomarkers of Brain Atrophy.
A poor nutrition status is a modifiable risk factor for cognitive decline and dementia. In particular, evidence links low status of certain B-vitamins and ω-3 fatty acids (ω-3 FA) with a greater risk of cognitive decline and…
- Trial name
- BOOMERANG (NCT07312435)
- Testing
- Intervention, Control
- Where
- Norway
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Old Age, Vestibular Disorder
Comparative Effects of Virtual Reality and Vestibular Exercises on Balance Gait in Older Adults
To compare the effects of virtual reality and vestibular exercises on balance, gait, and activities of daily living in older adults.
- Conditions
- Old Age, Vestibular Disorder, Balance, Exercise
- Trial name
- NCT06407726
- Testing
- virtual reality training group, vestibular exercise group
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Loneliness, Self-Efficacy
Digital Storytelling-Based Psychoeducation for Loneliness and Self-Efficacy in Adults Aged 65-74
This study is testing whether a psychoeducation program developed using digital storytelling affects loneliness and self-efficacy in adults aged 65 to 74.
- Trial name
- NCT07878715
- Testing
- Digital Storytelling-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Şura KILIÇ
Aging, Functional Status
Remote Physical and Cognitive Training Effects in Older Adults at Increased Risk of Clinical-functional Vulnerability
This study is a randomized, single-blind, parallel, controlled, superiority trial. The main objective is to verify the chronic effects of a remote 12-week low-intensity physical training program alone or in combination with…
- Trial name
- NCT05309278
- Testing
- Physical training, Cognitive training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Healthy
Lysine Requirement of Elderly Men and Women Over 60 Years of Age
This study aims to determine the requirement for lysine in men and women over the age of 60 years. Seven different levels of lysine intake will be tested in each subject in random order.
- Trial name
- NCT02008955
- Testing
- Lysine intake provided as a milkshake
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Malnutrition
Assessment of Food Practices by Residents in Nursing Homes
Nutrition is an essential component of health and a key determinant of aging and quality of life of individuals. Malnutrition in the elderly is now recognized as a public health problem affecting nearly half of residents in…
- Trial name
- ARC2 (NCT02626078)
- Testing
- observation and interview of residents
- Where
- 8 sites in France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pulmonary Embolism, Venous Thromboembolism
Rivaroxaban in Elderly Chinese Venous Thromboembolism Patients
There's no unified recommendation in clinical practice regarding adjusting dosages for different patient types, especially when adverse events occur.
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Anticoagulant-induced Bleeding
- Trial name
- NCT06194617
- Testing
- Direct oral anticoagulant
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Healthy Aging
Combined Exercise Trial
The number of older Americans will double in the next 4 decades to nearly 90 million, placing an unprecedented financial and resource burden on the health care system.
- Trial name
- COMET (NCT04848038)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Respiratory Syncytial Virus Infections
Safety and Efficacy of BARS13 in the Elderly
Advaccine Clinical Research are developing a vaccine called BARS13 for the active immunisation of infants (aged 6 months to 5 years old) and the elderly (aged 60-80 years old) for the seasonal prevention of Respiratory Syncytial…
- Trial name
- NCT04681833
- Testing
- Recombinant Respiratory Syncytial Virus Vaccine (BARS13)
- Where
- 2 sites in Australia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Advaccine (Suzhou) Biopharmaceuticals Co., Ltd.
Aging, Type2 Diabetes
Cardiovascular Risk and Functional Responses From Dancing at Home in the Elderly With and Without Type 2 Diabetes
The goal of this randomized controlled trial is to investigate the effects of a dance intervention performed at home, on cardiovascular risk factors and functional capacity of elderly individuals with and without type 2 diabetes…
- Trial name
- NCT04840368
- Testing
- Dancing
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Immune Response, Upper Respiratory Tract Infection
Walnut and Immunity Study
The main objective of the study is to determine if eating walnuts enhances immune function, in older free-living men and postmenopausal women with overweight.
- Trial name
- walnutimmune (NCT05915390)
- Testing
- walnuts, Habitual diet
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Healthy
The Effects of AR and VR Oral Care Training System on Oral Healthcare for Elderly in Eldercare Students
The aim of this study is to assess the effectiveness of an AR/VR oral care training system on the knowledge, attitudes, self-efficacy, and behavioral intentions of students majoring in geriatric care.
- Trial name
- NCT05958238
- Testing
- AR/VR oral care training system, Traditional classroom teaching
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cardiovascular Disease
Investigating the Effects of Green Tea on Blood Viscosity
A diet high in flavonoids is becoming more established as beneficial to human health. Recent data suggest that the regular consumption of flavanols can reduce the numbers of deaths by cardiovascular disease at a population level.
- Trial name
- NCT06740448
- Testing
- Green Tea, Control (Hot Water)
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
A Pilot Study of the Effects of BCG Immunization on CSF and Blood-based Biomarkers in Older Adults.
A pilot study of the effects of Bacillus Calmette-Guérin (BCG) immunization on cerebrospinal fluid and blood-based biomarkers in older adults.
- Trial name
- NCT04507126
- Testing
- Bacillus Calmette-Guerin (BCG)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dementia, Cognitive Impairment
Functionally-tailored Oral Care Intervention for Community-dwelling Older Adults With Dementia and Their Caregivers
The specific aims of this study are: Aim 1. Develop a staged and modifiable dyadic oral care intervention to provide functionally-tailored oral care rehabilitation for community-dwelling persons with dementia (PWD) and need-based…
- Trial name
- NCT04238520
- Testing
- Functionally Tailored Oral Care Intervention, Control Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Xi Chen
Accidental Falls, Old Age; Debility
Interventions to Prevent Falls. PRECAISAL Study
This study aims to guide older people living in the community on appropriate strategies within a fall prevention program. This program is aimed at training in physical exercises carried out through group workshops or at…
- Conditions
- Accidental Falls, Old Age; Debility, Activity, Motor
- Trial name
- NCT05070533
- Testing
- Individual treatment, Groupal treatment
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
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