Clinical trials: Advanced Age
Depressive Disorder, Suicide, Attempted
Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients
The main objective of this study is to show MRI functional and structural differences between depressed elderly patients with a history of attempted suicide compared to depressed elderly patients with no history of attempted…
- Trial name
- SPAD-IRM (NCT03287986)
- Testing
- MRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Older Adult
Community-based Physical Fitness Exercise on the Older Adults' Functional Fitness and Adherence to Physical Activity
Maintaining adequate physical activity (PA) and regularly exercising are very important to promote the good physical and mental health of the elderly.
- Trial name
- NCT05081505
- Testing
- Structural exercise course, Autonomous group class
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Diabetes, Healthy
Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy Volunteers
This trial is conducted in Europe. The aim of this trial is to compare the exposure of liraglutide in young versus elderly healthy subjects.
- Trial name
- NCT01507337
- Testing
- liraglutide
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Influenza, Human
A Study to Assess the Immunogenicity and Safety of CSL's 2012/2013 Formulation of Enzira® Vaccine in Healthy Volunteers
This is a study to assess the immune (antibody) response and safety of the 2012/2013 formulation of Enzira® (CSL Influenza vaccine) in healthy adult volunteers aged 18 years or older.
- Trial name
- NCT01591837
- Testing
- CSL Influenza Vaccine
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seqirus
Frailty, Aging
Effect of Multicomponent Exercises VIVIFRAIL® in Older Adults
This study employs a randomized, controlled, paired, single-blind clinical trial design. The targeted demographic comprises individuals aged 60 and above.
- Conditions
- Frailty, Aging, Physical Disability
- Trial name
- NCT06271239
- Testing
- Intervention group (ViviFrail), Group Suggestions for a Healthy Life (CG)
- Where
- 4 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Medication Adherence, Medication Compliance
Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays
Background: Problems with prospective memory, which refer to the ability to remember future intentions, cause deficits in basic and instrumental activities of daily living, such as taking medications.
- Trial name
- NCT04289246
- Testing
- Medication Ambient Display (MAD)
- Where
- Mexico
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Hepatitis B
Comparison of Immuno, Reacto and Safety of Recombinant Hepatitis B Vaccine With or Without MPL in Healthy Older Adults
In the present study the immunogenicity, reactogenicity and safety of recombinant hepatitis B vaccines with and without MPL will be evaluated in older healthy subjects
- Trial name
- NCT00697242
- Testing
- Engerix™-B, Recombinant HBsAg with different concentrations of Aluminium Salts and/or MPL
- Where
- 4 sites in Austria, Belgium and 2 more
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COPD
Inflammation in COPD and the Effect of Nicotinamide Riboside
The aim of this study is to investigate if nicotinamide riboside can reduce the airways inflammation associated with chronic obstructive pulmonary disease (COPD) in patients aged 60 or older.
- Trial name
- ICON (NCT04990869)
- Testing
- Nicotinamide Riboside
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Alzheimer Disease
Study Evaluating the Safety of Lecozotan SR in Healthy Young and Elderly Subjects
To assess the safety, tolerability and pharmacokinetics of single and multiple ascending oral doses of lecozotan SR in healthy young and elderly subjects.
- Trial name
- NCT00366483
- Testing
- Lecozotan SR
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Aging, Physical Activity
Exercise Intervention and Running Biomechanics in Older Adults
The goal of this study is to understand the effects of muscle strengthening and stretching exercise intervention on isometric muscle strength, joint flexibility and running biomechanical patterns in older recreational runners.
- Trial name
- NCT01574794
- Testing
- Muscle strengthening exercises, Muscle stretching exercise
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Respiratory Syncytial Virus (RSV)
A Study to Evaluate the Efficacy of an RSV F Vaccine in Older Adults
The purpose of this study is to demonstrate the efficacy of the RSV F vaccine at a dose of 135µg via intramuscular (IM) injection in the prevention of moderate-severe RSV-associated lower respiratory tract disease (RSV-LRTD) in…
- Trial name
- NCT02608502
- Testing
- RSV-F Vaccine
- Where
- 60 sites in United States
- Volunteers
- 11,850 people, healthy volunteers welcome
- Sponsor
- Novavax
Osteoarthritis
Visual Feedback Non-weight Bearing Exercise on the Elderly With Knee Osteoarthritis.
Degenerative knee arthritis is the most common chronic arthritis disease. Once the elderly suffer from this disease, it will accelerate the loss of body function and autonomy.
- Trial name
- NCT04919486
- Testing
- visual feedback with non-weight bearing exercise, elastic band exercise
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Depression
Study of the Effect of a Cognitive Task on Static Balance in Depressive Elderly Subjects According to the Double Task Principle
This study could contribute to understanding the aggravation of balance disorders and the increased risk of falling in depressive people.
- Trial name
- DOUBLE TACHE (NCT01950754)
- Testing
- standing with both feet, descent of the platform, standing on the platform, feet together and always with simultaneous performance of a task of mental count
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Elderly
Effects of Training in a Virtual Environment in Healthy Elderly
The objective of this work was to compare the effects of two balance training programs, one Nintendo Wii Fit-based and the other traditionally-based without the use of a gaming system, on the (1) balance, (2) gait, (3)…
- Trial name
- NCT01741402
- Testing
- Virtual Reality Training, Physical Therapy
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
Arm Motor Rehabilitation, Entertainment and Cognition System for the Elderly.BAC.U
This usability study is to test the basic functionality of the BrightArm Compact (BAC) system. The BAC is a motorized rehabilitation platform to offer gravity bearing for weak upper extremity.
- Trial name
- NCT04252196
- Testing
- usability evaluation of medical device
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bright Cloud International Corp
Influenza
Eldery High Dose TIV 2005
The purpose of this study is to compare a new higher-dose influenza virus vaccine to the standard dose vaccine in elderly adults who can walk.
- Trial name
- NCT00115531
- Testing
- Trivalent inactivated influenza vaccine
- Where
- 5 sites in United States
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Mild Cognitive Impairment, Randomized Controlled Trial
Cognitive Stimulation in Older With Mild Cognitive Impairment
The participants who carry out our program of cognitive stimulation, deteriorate at a cognitive level more slowly and can improve their score of the Spanish version of 35 points of Mini-mental State of Folstein; Mini-exam…
- Trial name
- Cognitive (NCT03831061)
- Testing
- Cognitive stimulation
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Elderly, Acetabular Fractures
Acetabular Cerclage and Total Hip Arthroplasty in the Treatment of Acetabular Fractures in Elderly Patients.
We want to present the outcome of complex multifragmented acetabular fractures in the elderly treated with acetabular cerclage and total hip arthroplasty.
- Conditions
- Elderly, Acetabular Fractures, Cerclage Acetabular Fractures, Total Hip Arthroplasty
- Trial name
- jantjeVL (NCT03581669)
- Testing
- Cerclage and total hip arthroplasty
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Aging, Aging Problems
Gaming Applied to the Promotion of Active Aging
Active aging programs have been recommended by the World Health Organization to help deal with the progressive aging of the population. However, older adults have difficulties in accessing these programs.
- Trial name
- GAMAPEA (NCT03643237)
- Testing
- Video game-based intervention, Control group
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Sense of Community
Community Spirit in Residence for the Elderly
The objective of our study is to observe and understand factors that emphasizes the creation of a community spirit. Specific objectives: 1.
- Trial name
- 437_EsCom (NCT06441877)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- TOPMED
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