Clinical trials: Advanced Keratoconus
Keratoconus
Treatment of Keratoconus With Advanced CXL-II
The purpose of this study is to determine whether individualized, topography-based corneal crosslinking for keratoconus can improve the optical outcomes of the treatment.
- Trial name
- NCT02514200
- Testing
- Topography-based CXL (KXL2), Conventional pulsed CXL (pCXL), Riboflavin
- Volunteers
- 50 people
- Sponsor
- Umeå University
Advanced Keratoconus
Isolated Bowman Layer Graft for Reducing and Stabilizing Advanced Keratoconus
To evaluate the efficacy of mid-stromal implantation of an isolated Bowman layer graft, to reduce and stabilize ectasia in eyes with advanced keratoconus
- Trial name
- NCT01686906
- Testing
- Bowman layer graft implantation
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- Netherlands Institute for Innovative Ocular Surgery
Progressive Keratoconus
Efficacy and Safety ofCACXL in the Treatment of Keratoconus With Thin Corneas
The aim of this study is to detect the safety and effectiveness of contact lens assisted corneal cross linking in managing progressive keratoconus with thin corneas CACXL was done for 40 eyes of 30 of keratoconic patients…
- Trial name
- CACXL (NCT04504578)
- Testing
- contact lens assisted corneal cross linking
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Keratoconus
Treatment of Keratoconus With Advanced Corneal Crosslinking
The purpose of this study was to determine whether mechanical compression of the cornea during corneal crosslinking for keratoconus using a sutured rigid contact lens can improve the optical outcomes of the treatment.
- Trial name
- NCT02425150
- Testing
- Corneal reshaping/crosslinking (CRXL), Corneal Crosslinking (CXL)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Umeå University
Ophthalmological Disorder, Corneal Dystrophy
Autologous Adipose-Derived Adult Stem Cell Implantation for Corneal Diseases (ADASCs-CT-CD)
Cellular therapy of the corneal stroma with implantation of mesenchymal stem cells derived from autologous adipose tissue with or without a carrier (scaffold) composed by decellularized human donor corneal stroma is used in…
- Conditions
- Ophthalmological Disorder, Corneal Dystrophy, Treatment, Therapy
- Trial name
- ADASCs-CT-CD (NCT05279157)
- Testing
- Implantation, Lipoaspiration
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Vissum, Instituto Oftalmológico de Alicante
Keratoconus, Keratoconus of Right Eye
Fresh Corneal Lenticule Implantation and Autologous Serum - Case Report
The aim of our study is to investigate the feasibility and the effect of fresh lenticule implantation as allogenic graft that will be taken from myopic patients to implant in patients with keratoconus disease using VisuMax…
- Conditions
- Keratoconus, Keratoconus of Right Eye, Keratoconus, Unstable, Right Eye
- Trial name
- NCT04594512
- Testing
- Fresh corneal lenticule and autologous serum in advanced keratoconus using ReLex Smile surgery
- Where
- Kosovo
- Volunteers
- 1 people
- Sponsor
- Eye Hospital Pristina Kosovo
Keratoconus, Astigmatism High
Enhancing Scleral Lens Fit With Advanced Imaging
The goal of this experimental clinical trial is to enhance the predictability and precision of scleral lens fitting in patients with complex corneal conditions such as keratoconus, post-surgical irregularities, and severe dry eye…
- Trial name
- SPLEPICA (NCT06751615)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fernando Fernandez Velazquez
Keratoconus, Corneal Cross-Linking
Surface Ablation With Corneal Cross Linking in Mild Keratoconus
Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) will be divided into four groups.
- Trial name
- NCT05176171
- Testing
- Photorefractive Keratectomy with Corneal Cross-Linking
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University