Clinical trials: Advanced Right-sided Colon Cancer
Colorectal Cancer (CRC)
Toripalimab Plus Cetuximab and Irinotecan for Second-Line Right-Sided RAS/BRAF Wild-Type Advanced Colon Cancer Phase II Study
This phase II, single-arm clinical study aims to evaluate the efficacy and safety of toripalimab combined with cetuximab and irinotecan as second-line treatment for patients with advanced right-sided colon cancer with wild-type…
- Trial name
- NCT07896681
- Testing
- Toripalimab, Cetuximab, Irinotecan
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Colonic Neoplasms
Cetuximab in Combination With Anti-PD-1 and mFOLFOX Treat For RAS/BRAF wt Right-Sided Colon Cancer
We plan to evaluate the efficacy and safety of cetuximab combined with anti-PD-1 and mFOLFOX6 in the treatment of RAS/BRAF WT locally advanced or metastatic right colon cancer
- Trial name
- CIFOXRC (NCT05468177)
- Testing
- neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Tongji Hospital
Colorectal Cancer
Anti-EGFR Agents in Patients With Right-sided Advanced Colorectal Cancer With Wild-type RAS and AREG/EREG High Status
The aim of this trial is to assess the feasibility of EREG/AREG assessment as a clinical diagnostic standard, used to guide clinical decision making in right-PTL, RAS-wt aCRC.
- Trial name
- ARIEL-ENGIC (NCT07094893)
- Testing
- Cetuximab (EGFR inhibitor), Bevacizumab, Irinotecan (CPT-11)
- Volunteers
- 280 people
- Sponsor
- Gruppo Oncologico del Nord-Ovest
Right Hemicolectomy
Fluorescence Lymph Node Mapping for Colon Cancer Surgery
Fluorescence-guided surgery using indocyanine green can visualize the complex and diverse lymph node drainage structures for each patient and help determine the extent of dissection of the D3 lymph node tailored to the patient.
- Trial name
- CONSTELLARE (NCT07060443)
- Testing
- Indocyanine green (ICG) injection for intraoperative lymph node imaging, Standard Right Hemicolectomy (Non-ICG)
- Where
- 13 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Pusan National University Yangsan Hospital
Colon Cancer
Mesogastrium Metastasis in Colon Cancer
Complete mesocolic excision is currently recognized as a standard procedure for colon cancer. Controversy remains on the presence of right gastroepiploic mesentery metastasis in patients with colon cancer locating at or close to…
- Trial name
- NCT04980287
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Jichao Qin
Advanced Right-sided Colon Cancer, the Extent of Lymph Node Dissection
Extent of Lymph Node Dissection for Advanced Right-Sided Colon Cance
This is a prospective multicenter randomized controlled clinical study to explore the extent of lymph node dissection in progressive right hemicolon cancer and to elucidate the pattern of lymphatic drainage in the right hemicolon.
- Trial name
- MARCH (NCT06986538)
- Testing
- Clearance with the left side of the SMV as the medial boundary, Clearance with the left side of the SMA as the medial boundary
- Where
- 26 sites in China
- Volunteers
- 1,064 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Colon Cancer
Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer
The study was conducted on patients with advanced right-sided colon cancer, and the clinical pathological and prognostic data of the patients were compared between the two groups of patients who were randomly divided into those…
- Trial name
- BLARCC (NCT06709144)
- Testing
- SMA lymph node dissection, SMV lymph node dissection
- Where
- China
- Volunteers
- 896 people
- Sponsor
- Haixing Ju, MD