Clinical trials: Adverse Childhood Experience
Adverse Childhood Experiences
Implementation of Adverse Childhood Experiences (ACEs) Policy
Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology.
- Trial name
- NCT04916587
- Testing
- Implementation Strategy of ACEs Screenings, Usual Care
- Where
- United States
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adverse Childhood Experiences
Playing Playfully to Overcome Adversity
This research project was developed in an effort to support teachers of young children exposed to adversity and to assist them with enhancing children's development through play.
- Trial name
- PPOA (NCT06985017)
- Testing
- Playing Playfully to Overcome Adversity
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Sacred Heart University
Obesity, Adolescent
Piloting a Biofeedback Intervention for Adolescents With Overweight and a History of Adverse Childhood Experiences
Adverse childhood experiences (ACEs), referring to traumatic experiences occurring before 18 years of age (e.g., abuse/neglect), are associated with a 30-70% increased risk of developing adolescent and adult obesity and…
- Trial name
- NCT05984043
- Testing
- Biofeedback, Waitlist
- Sponsor
- Colorado State University
Emotion Regulation, Adverse Childhood Experience
Paired Emotion Reading Improves Emotion Regulation in Rural Children With ACE
The goal of this study is to explore the feasibility and effectiveness of the online Paired Emotion Reading Intervention (PERI) on the emotion regulation of rural children with adverse childhood experiences (ACE), as compared…
- Trial name
- NCT06505629
- Testing
- the online Paired Emotion Reading Intervention (PERI), the online Paired General Reading Intervention (PGRI)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University
Adverse Childhood Experiences
ACE, Resilience, and Substance Use Disorder: Maternal and Baby Outcomes in the First Year of Life
The purpose of this study is to understand maternal factors, including ACE and 7Cs Tool scores, and how they contribute to the health of mothers and their infant.
- Trial name
- NCT05731557
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Adverse Childhood Experiences
ACEs Referral From PED
Adverse childhood experiences (ACEs) are traumatic exposures that can cause many negative health impacts across life. ACEs are common in patients who seek out care in pediatric emergency departments (PEDs); this is an opportunity…
- Trial name
- NCT06574633
- Testing
- In-person therapy, Telehealth therapy
- Where
- 4 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Emory University
Adolescent Behavior, Stress Reduction
CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention
Using an adapted stress-reduction intervention called the CEDARS, the investigators will pilot the intervention in adolescents (N=40) to determine the feasibility and acceptability of CEDARS implementation and to investigate…
- Conditions
- Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
- Trial name
- CEDARS (NCT04958694)
- Testing
- CEDARS
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Adverse Childhood Experiences
Childhood Trauma, Exercise, and Cognition
This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood.
- Trial name
- CTEC (NCT05972265)
- Testing
- Moderate Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Drug Addiction
Construction of Early Warning Model for the New Psychoactive Substances Using in Adolescents
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old.
- Trial name
- NCT05958641
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Adverse Childhood Experiences, Vascular Dilatation
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
The overall purpose of this study is to understand the role of disrupted sleep in the association of exposure to early life adversity (adverse childhood experiences (ACEs)) with vascular endothelial (dys)function.
- Conditions
- Adverse Childhood Experiences, Vascular Dilatation, Sleep, Sleep Disturbance
- Trial name
- NCT06454344
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-i)
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism, Adverse Childhood Experience
A Two-Part Intervention to Target Cardiovascular Health
Obesity is one of the most common health conditions among autistic young people and its prevalence rises at faster rates for autistic-relative to non-autistic-individuals.
- Conditions
- Autism, Adverse Childhood Experience, Stress, Cardiovascular (CV) Risk
- Trial name
- NCT07673172
- Testing
- Lifestyle Medicine, Cognitive Behavioral Therapy (CBT), Lifestyle Medicine with CBT Group
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, Los Angeles
Hunger, Child Development
Building Wealth and Health Network: A Microfinance/TANF Demonstration Project
The goals of the The Building Wealth and Health Network (The Network) are to develop and rigorously test an asset building model that will build financial, social and human capital through asset building, financial education and…
- Conditions
- Hunger, Child Development, Social Isolation
- Trial name
- NCT02577705
- Testing
- Self Empowerment Groups, Financial Empowerment, Matched Savings
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Center for Hunger-Free Communities
Sickle Cell Disease, Adverse Childhood Experiences
Early Life Exposures Among Children With Sickle Cell Disease
This study is being conducted to determine the relationship between early childhood exposures, such as Adverse Childhood Experiences, Social Determinants of Health and nutrition/breastfeeding, among children with sickle cell…
- Conditions
- Sickle Cell Disease, Adverse Childhood Experiences, Breastfeeding
- Trial name
- NCT05377372
- Testing
- Breastfeeding support group, Observation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Lower Urinary Tract Symptoms (LUTS), Transition Care
Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent Years
With this study, we would like to interview 16-25-year-olds who have experienced urinary problems since childhood and who are still experiencing symptoms in young adulthood.
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Transition Care, Enuresis Nocturnal, Adverse Childhood Experiences
- Trial name
- STREAMWAY (NCT07339865)
- Testing
- Semi-structured in-depth interviews with standardized validated questionnaires, Completion of a urological time-line
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Depression in Adolescence, Adverse Childhood Experiences
Life Experiences in Adolescents and the Development of Skills
The primary objective of this study is to assess acquisition and retention of a Cognitive Behavioral Therapy (CBT)-based "cognitive restructuring" skill, among young adolescents (12-15 years of age) with elevated depression…
- Trial name
- LEADS (NCT04719897)
- Testing
- FIRST: Repairing Thoughts
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Pittsburgh
Adverse Childhood Experiences and Adolescent Mental Health
Self-Compassion Based Psychoeducation Program for Adolescents With Adverse Childhood Experiences
This randomized controlled experimental study examined the effects of a brief self-compassion intervention program (BSCIP) on mental health outcomes among adolescents reporting four or more adverse childhood experiences (ACEs).
- Trial name
- BSCIP-ACE (NCT07875439)
- Testing
- Brief Self-Compassion Intervention Program (BSCIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ahmet Alkal
Alcohol-Induced Disorders, Ostracism
Role of Adverse Childhood Events and Rejection Sensitivity on Alcohol Use in Recently Withdrawn Individuals With Alcohol Use Disorder
Low utilization of addiction treatment is a public health problem. A number of factors are associated with lack of treatment, including public stigma, self-stigma, and beliefs that people with addiction should solve their problem…
- Trial name
- TRAC (NCT05787106)
- Testing
- Cyberball task
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Subthreshold Depression
A Pilot Study to Examine the Efficacy of Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression
The present study aims to pilot internet-delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) as a transdiagnostic emotion dysregulation intervention to prevent progression to depression in individuals…
- Trial name
- NCT07118072
- Testing
- Internet-Delivered Skills Training in Affective and Interpersonal Regulation, Online general psychoeducation
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- Institute of Mental Health, Singapore
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Adverse Childhood Experiences, Child Development
Testing a Scalable Model For ACEs-Related Care Navigation
The study is a randomized controlled trial of a telephone-based care coordination system for families who experienced Adverse Childhood Events (ACEs).
- Trial name
- NCT05567250
- Testing
- Behavioral: Telephone-based ACEs care coordination
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles