Clinical trials: Adverse Childhood Experiences
Adverse Childhood Experiences
Implementation of Adverse Childhood Experiences (ACEs) Policy
Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology.
- Trial name
- NCT04916587
- Testing
- Implementation Strategy of ACEs Screenings, Usual Care
- Where
- United States
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parent-Child Relations, Maternal Behavior
A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity
Childhood adversity affects almost two-thirds of the US population, is a major risk factor for the leading causes of disease and increases US economic health burdens.
- Conditions
- Parent-Child Relations, Maternal Behavior, Infant Behavior
- Trial name
- NCT04818112
- Testing
- ATVV, Attention control
- Where
- 2 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Infant Mortality, Infant Death
Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)
This pilot project aims to implement and investigate the feasibility and acceptability of a unique community based prenatal care and support model for African American women and infants in Dane County.
- Conditions
- Infant Mortality, Infant Death, Racial Bias, Prenatal Stress
- Trial name
- NCT04100577
- Testing
- Today Not Tomorrrow Pregnancy and Infant Support Program
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility, Female, Trauma, Psychological
Adverse Childhood Experiences and Infertility : ACESI
Adverse childhood experiences can have powerful effects on health and quality of life in adulthood. Thus, having a history of childhood trauma, before the age of 18 (physical aggression, sexual abuse, death of a close person…
- Conditions
- Infertility, Female, Trauma, Psychological, Child Development, Child Abuse
- Trial name
- ACESI (NCT05952427)
- Testing
- ACE Questionnaire
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Child Abuse
Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences
The goal of this observational study is to assess the American Psychological Association's ACT Raising Safe Kids program with male caregivers.
- Trial name
- CAD (NCT06075446)
- Testing
- ACT Raising Safe Kids
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Opioid Use Disorder, Healthy
Adversity, Brain and Opioid Use Study
The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms.
- Trial name
- NCT06355778
- Testing
- Magnetic Resonance Imaging (MRI), Computer Tasks
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cognitive Aging, Adverse Childhood Experiences
Physical Exercise for Augmenting Cognitive Health (PEACH)
PEACH is a pilot project which is being conducted to determine the feasibility and acceptability of a 12-week home-based exercise intervention among Black and African American adults.
- Trial name
- PEACH (NCT04922710)
- Testing
- Home-based aerobic exercise
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Adverse Childhood Experiences, Child Development
Testing a Scalable Model For ACEs-Related Care Navigation
The study is a randomized controlled trial of a telephone-based care coordination system for families who experienced Adverse Childhood Events (ACEs).
- Trial name
- NCT05567250
- Testing
- Behavioral: Telephone-based ACEs care coordination
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Adverse Childhood Experiences, Family Functioning
The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments
The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among…
- Trial name
- NCT06821035
- Testing
- Garnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Psychological Wellness
Resilient Students Training (ReST) : A Pilot RCT
Resilience is the ability to survive and thrive despite significant adversity. Trials of resilience-promoting interventions for university students have shown significant improvements in students' resilience and reductions in…
- Trial name
- ReST (NCT06157931)
- Testing
- Resilient Student Training intervention (ReST)
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder, Adverse Childhood Experiences
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Using a metabolomics approach in combination with eye-tracking data, this research study proposes to gather evidence from two interrelated body systems (gut and brain) in order to assess how the microbiome is involved in stress…
- Conditions
- Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
- Trial name
- NCT06269614
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Adverse Childhood Experiences, Mindfulness
Approaches That Support Mental Health in Post-secondary Students With Adverse Childhood Experiences
The objective of this study is to understand the prevalence of adverse childhood experiences (ACE) in students and to determine whether Mindfulness based stress resilience training (MBSR) is effective for promoting mental health…
- Conditions
- Adverse Childhood Experiences, Mindfulness, Students
- Trial name
- ACE (NCT03836456)
- Testing
- Mindfulness-based Stress Resilience Training, Health Enhancement Program
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Pelvic Floor Disorders, Interstitial Cystitis
Adverse Childhood Experiences in Urogynecologic Patients
Adverse Childhood Experiences (ACEs) have been associated with negative health outcomes, yet scant information exists regarding the relationship between ACEs, Pelvic floor disorders, and Chronic Pelvic Pain.
- Conditions
- Pelvic Floor Disorders, Interstitial Cystitis, Urinary Incontinence
- Trial name
- ACE-UP (NCT03480477)
- Testing
- ACE questionnaire
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Mental Health Issue, Adverse Childhood Experience
Chinese Community Sample of Hierarchical Model of Psychopathology
By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems…
- Trial name
- NCT06105970
- Testing
- No intervention
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Life Change Events, Loneliness
Me and the Others: Expectations and Evaluation of Social Relationships
Chronic and pervasive loneliness has been identified as an important factor in the relationship between adverse childhood experiences (ACE) (e.g. abuse and neglect) and mental disorders.
- Trial name
- NCT03764566
- Testing
- Questionnaires
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Adverse Childhood Experiences
Family Resilience Initiative Research Program
University Le Bonheur Pediatric Specialists (ULPS) and Le Bonheur Community Health and Well-Being, Maternal Child Department, have started the Family Resilience Initiative (FRI) in the ULPS General Pediatrics Clinic.
- Trial name
- NCT04018404
- Testing
- FRI CLINICAL PROGRAM
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Adverse Childhood Experiences
Childhood Trauma, Exercise, and Cognition
This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood.
- Trial name
- CTEC (NCT05972265)
- Testing
- Moderate Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin