Clinical trials: Adverse Drug Effect of Opioids
Pain, Postoperative
Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?
The study aims to compare the use of intravenous patient controlled analgesia (IVPCA) versus the delivery of pain relief (per oral and intravenous (IV) medications as rescues analgesia) on an as needed basis within a well defined…
- Trial name
- NCT02880800
- Testing
- Morphine as IVPCA, Hydromorphone as IVPCA, Morphine
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Adverse Drug Effect of Opioids, Adverse Drug Effect of Benzodiazepines
Reducing Concurrent Opioid-Benzodiazepine Prescriptions
The purpose of this effort is to use informative e-mails to improve the process of prescribing of opioids and benzodiazepines within the National Capital Region/Military Health System (NCR/MHS), with the aim of decreasing…
- Trial name
- NCT03887247
- Testing
- E-mail Alert
- Where
- United States
- Volunteers
- 2,234 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang