Clinical trials: Aerobic Exercise
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Concussion, Brain
Salivary Biomarkers for Concussion Recovery
The overarching purpose of this proposed research is to determine whether BDNF and/or specific miRNAs can serve as biomarkers for recovery from a concussion during prescribed exercise.
- Trial name
- NCT05379920
- Testing
- High Volume Aerobic Exercise, Low Volume Aerobic Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Alzheimer's Disease
Dose Response Study of Aerobic Exercise in Older Adults
This is a randomized, 26-week study of supervised exercise assessing three doses of exercise in sedentary individuals 65 years of age and over with age-related cognitive changes.
- Trial name
- NCT01129115
- Testing
- Nonexercise control group, Aerobic Exercise Group 1, Aerobic Exercise Group 2
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Jeff Burns, MD
Alzheimer's Disease, Aging
aeRobic Exercise and Cognitive Health
The purpose of the aeRobic Exercise and Cognitive Health (REACH) study is to understand how an aerobic exercise intervention might help promote brain health and cognition, thereby delaying the onset of clinical symptoms of…
- Trial name
- REACH (NCT02384993)
- Testing
- Enhanced Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sedentary Lifestyle
Aerobic Exercise and Cognitive Training in Older Adults
The purpose of this study is to examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
- Trial name
- NCT02787655
- Testing
- Aerobic exercise + Cognitive Training Group, Cognitive training Only
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pain
Exercise Dosing for Pain in Healthy Participants
In this study investigators will examine the effect of dose related to exercise therapy for pain in healthy adult humans. An acute pain model will be employed to study the effect of exercise dose on pain.
- Trial name
- NCT03642938
- Testing
- Walking Exercise, Control
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Aging, Aphasia
Exercise Effects on Word Learning
The aging Veteran population will substantially increase over the next 10 years, as the 24.9% of Veterans who are currently between 55-64 years of age join the 38.5% who are already over age 65.
- Trial name
- NCT03370471
- Testing
- Retrieval Practice + Moderate Intensity Exercise, Retrieval Practice + Gentle Stretching, Study Only + Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV Infections
Exercise, Oxidative Stress and HIV
The purpose of this study is to compare oxidative stress markers and the immunologic characteristics of HIV-infected and non-HIV subjects during a bout of moderate aerobic exercise followed by resistance exercises
- Trial name
- NCT00950937
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Physical Activity
Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin
The investigators propose that post-exercise milk protein feeding will enhance the mitochondrial protein synthesis (biogenesis) response to an exercise-training program.
- Trial name
- NCT02552355
- Testing
- Metformin, Carbohydrate Beverage, Protein Beverage
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Aging
Aerobic Exercise and Cerebrovascular Function
This proposal will evaluate two brain health measures, cerebrovascular perfusion and cerebrovascular reactivity (CVR), before and after a proven, interval-based, aerobic exercise intervention in older Veterans.
- Trial name
- NCT03803904
- Testing
- Spin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging
Sex Differences in Vascular Responses to Exercise
A key early event in cardiovascular disease development is endothelial dysfunction, characterized by impaired flow-mediated dilation.
- Trial name
- NCT04128215
- Testing
- Control Period, Exercise Period
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging
Aerobic Exercise to Improve Executive Language Function In Older Adults
The purpose of this study is to see if exercise can improve brain function in older adults
- Trial name
- NCT00979069
- Testing
- Aerobic group
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Traumatic Brain Injury (TBI)
Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI
Background: Traumatic brain injury (TBI) often causes problems with moving and balance, and thinking and emotions. Exercise can improve these things in people with other brain damage.
- Trial name
- NCT02504866
- Testing
- Vigorous exercise, Light to moderate exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Insulin Resistance, Type 2 Diabetes
Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men
The purpose of this study is to investigate the effect of an exercise training intervention on the ability of African American males to use insulin properly. Insulin is a hormone that helps the body use glucose.
- Trial name
- ARTIIS (NCT01787617)
- Testing
- Aerobic Plus Resistance Training Group, Control Group
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Prediabetic State
Medium Chain Triglycerides and Aerobic Exercise on Ketone Production in Women With or Without Prediabetes
The aim of this study is to compare the effect on ketone production of dietary an MCT supplement combined or not with physical exercise in two groups of women (N=10/group), healthy adults and patients with prediabetes.
- Trial name
- MCT+AE (NCT02678390)
- Testing
- MCT, MCT+ aerobic exercise, Aerobic exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Cardiovascular Health, Sleep
Aerobic Exercise: A Potential Rescue From the Negative Ramifications of Poor Sleep
The goal of this interventional study is to differentiate the effects of an acute partial sleep deprivation intervention on markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well…
- Trial name
- NCT06956963
- Testing
- Partial Sleep Deprivation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Florida State University
Type 2 Diabetes Mellitus, Impaired Glucose Tolerance (Prediabetes)
Exercise Training and Glucose Metabolism in Aging
Diabetes and its associated complications affect more than 20 million Americans, and the prevalence of type 2 diabetes and impaired glucose tolerance rises dramatically with age such that 40% of Americans over age 60 are…
- Trial name
- NCT00701051
- Testing
- Aerobic exercise training, Detraining (cessation of exercise)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Eating Disorders
Response to Acute Exercise in Eating Disorders
Individuals with eating disorders (ED) represent a high-priority clinical population, with among the highest mortality rates of any psychiatric disorder, and driven exercise (DEx) is a symptom evidenced in up to 80% of those with…
- Trial name
- NCT06213883
- Testing
- Biobehavioral Response to in-lab exposure to physical activity
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Stress, Psychological
Yoga and Aerobic Exercise Effects on Cognition
The purpose of this acute randomized control study is to assess the feasibility of a low-to-moderate intensity Yoga intervention (i.e.
- Trial name
- NCT04077645
- Testing
- Sun salutations, Aerobic exercise, Seated rest
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign