Clinical trials: Aesthetic Evaluation
Implant Site Reaction
the Peri-implant Tissue Changes Around Implants in the Esthetic Zone Using Demineralized Dentin Graft vs Xenograft
Dentin grafts are categorized into mineralized dentin, partially demineralized dentin matrix (PDDM), and demineralized dentin matrix (DDM).
- Trial name
- NCT06164353
- Testing
- Partially demineralized dentin graft covered with a collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Three Approaches of Resin Infiltration for MIH Incisor Opacities
Molar incisor hypomineralization (MIH) is a condition which involves enamel hypomineralization of one to four first permanent molars with or without permanent incisors.
- Trial name
- NCT07715370
- Testing
- Resin infiltration, microabrasion, Etch-bleach
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aesthetics
Long Term Safety and Efficacy Assessment of Hyaluronic Acid Dermal Filler With for the Treatment of Nasolabial Folds
This study evaluates the injection of a hyaluronic acid dermal filler with lidocaine 0.3% in the treatment of nasolabial folds (NLF).
- Trial name
- ECLAH (NCT02703740)
- Testing
- Hyaluronic acid dermal filler with lidocaine 0.3%
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laboratoires Genévrier
Gingival Papillary Blunting
Effect of Different Suturing Technique on Height of Interdental Papilla and Periodontal Healing
Comparative clinical evaluation of internal mattress sutures vs continuous independent sling sutures on interdental papilla height and periodontal healing in esthetic zone.
- Trial name
- NCT03429764
- Testing
- CISS, VIMS
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Nasolabial Folds
Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
This study has been designed to evaluate the safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the…
- Trial name
- NCT03780244
- Testing
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Cosmetic Techniques
Prospective Evaluation of Facial Cosmetic Procedures
A prospective, trial to quantitatively and qualitatively compare the dermal fillers for the treatment of age related aesthetic changes.
- Trial name
- NCT03460158
- Testing
- Restylane-L®, Restylane-L® Lyft, Restylane Silk®
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aesthetic Outcome of Crowns on Implants
Evaluation of the Aesthetic Outcome of Lithium Disilicate (e.Max) All Ceramic Crowns on Titanium Implant Abutments in the Aesthetic Zone After Different Color Masking Approaches
Implants have become the perfect solution for replacement of missing single teeth, partial or even complete edentulism.18 However, the dilemma of anterior implant-supported prosthesis is still not quite solved.19-21 Implant…
- Trial name
- NCT03686267
- Testing
- opaqued titanium abutments, lithium disilicate coping (high opacity), titanium abutment with no color masking
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gummy Smile, Altered Passive Eruption of Teeth
Clinical Evaluation of Gingivalstat Approach Compared to Conventional Esthetic Crown Lengthening on the Stability of The Gingival Margin in Patients With Altered Passive Eruption.
When performing crown lengthening surgery, especially in the esthetic zone, the positional stability of gingival tissues is considered a prime important goal.
- Conditions
- Gummy Smile, Altered Passive Eruption of Teeth, Healthy Participants
- Trial name
- NCT07041541
- Testing
- Esthetic Crown Lengthening, Esthetic Crown Lengthening using GingivalStat approach
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bilateral Breast Augmentation
Evaluation of the Safety and Performance of SYMATESE AESTHETICS ESTYME® MATRIX Round Microtextured Silicone Gel-Filled Breast Implants in the Breast Augmentation
The purpose of this study is to collect clinical data to evaluate the safety and performance of ESTYME® MATRIX Round microtextured breast implants in patients who receive these silicone gel-filled implants as part of their breast…
- Trial name
- EMMA (NCT05336526)
- Testing
- ESTYME® MATRIX Round Microtextured Silicone Gel-Filled Breast Implants
- Where
- 6 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Symatese Aesthetics
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Alveolar Cleft Grafting
Alveolar Cleft Grafting Using Two Different Alloplastic Grafts
P-patients with unilateral alveolar clefts I-purabone with -β-tricalcium phosphate graft C-β-tricalcium phosphate graft alone O-clinical out come Outcome name Measurement device Measurement unit Esthetic satisfaction (Primary…
- Trial name
- NCT03016793
- Testing
- Puerarin, β- tricalcium phosphate, β- tricalcium phosphate alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Diseases
Evaluation Between Zirconia and Stainless Steel Crowns
Introduction and Research Problem: The aim of this project is to evaluate and compare two full coronal restorations on primary posterior molars over a period of 3, 6 and 12 months in terms of restoration failure, marginal…
- Trial name
- NCT03067337
- Testing
- Stainless Steel Crown (Group A), NuSmile Zirconia Crowns (Group B)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dermal Filler, Rejuvenation
A Prospective Evaluation of Infraorbital Filler Injection
The goal of this clinical trial is to measure the facial volumetric changes over time in patients injected with hyaluronic acid dermal filler (Juvéderm Volbella XC) in the infraorbital (under eye) region.
- Trial name
- NCT05694286
- Testing
- Juvederm Volbella XC hyaluronic acid dermal filler injection
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aesthetics, Intradermal Injections
Clinical Evaluation of the Safety and Performance of a Filler in Correction of Mid-face Age-related Volume Deficit
Prospective, single center study, on healthy subjects to evaluate the aesthetic improvement of facial volume, effect on the restoration and/or augmentation in subjects with mid-face age-related volume deficit after injection of a…
- Trial name
- NCT04505319
- Testing
- DEFINISSE CORE FILLER
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Relife S.r.l.
Dental Implants, Immediate Implant Soft Tissue Healing
Effectiveness of ALB-PRF With Two Types of Bone Grafts With Putty Form Around Immediate Dental Implants.
The goals of this clinical trial study is to evaluate the additive effect, of using ALB-PRF membrane combined with two different types of bone grafts with putty form in treatment of peri-implant bony defects around immediate…
- Conditions
- Dental Implants, Immediate Implant Soft Tissue Healing, Immediate Implant With Bone Graft
- Trial name
- ALB-PRFE-PRF (NCT06643468)
- Testing
- participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and collagen membrane., participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and ALB- PRF as membrane., participants will receive immediate implant with beta-tricalcium phosphate + calcium sulphate bone graft and collagen membrane.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cleft Lip and Palate, Social Isolation
Perception of Appearance and Social Acceptance Between Cleft and Non-Cleft Children in Early Adolescence
Background: Using three-dimensional (3D) surface imaging, this study aims to understand the differences in perception between schoolchildren with and without cleft lip and palate (CLP), as well as to explore peer awareness and…
- Trial name
- Cleft social (NCT06539572)
- Testing
- Cleft lip repair; palatoplasty; alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mucogingival Defects, Pontic Site Development
Pontic Site Development With or Without Fixed Partial Denture
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects.
- Conditions
- Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
- Trial name
- Pontic Site (NCT07535060)
- Testing
- Connective Tissue Graft (CTG)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Wrinkle
Efficacy and Safety Study of SkinPlus-Hyal® to Nasolabial Fold
Study design:Multi-center, randomized, double-masked (Unblinded treating investigators), intra-individual comparison clinical trial
- Trial name
- NCT01940575
- Testing
- SkinPlus-Hyal®, Restylane®
- Where
- 2 sites in South Korea
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Aesthetic Improvement of the Skin, Skin Hydration in Healthy Volunteers
Clinical Investigation on a Polynucleotide-based Device Used to Improve Skin Hydration
Adequate skin hydration is critical for maintaining healthy skin. Moreover, dehydration, together with reduction in cell renewal, loss of radiance, elasticity and firmness, is involved in skin aging.
- Conditions
- Aesthetic Improvement of the Skin, Skin Hydration in Healthy Volunteers, Skin Elasticity, Skin Turgor
- Trial name
- NCT07151859
- Testing
- PN30 (RDM16)
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Mastelli S.r.l