Clinical trials: Aetiology
Hyponatremia, Hyponatremia With Extracellular Fluid Depletion
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status
Hyponatremia is the most frequent electrolyte disorder encountered in clinical practice. The patient approach, however, is still problematic, above all because hyponatremia is a manifestation correlated to various pathological…
- Conditions
- Hyponatremia, Hyponatremia With Extracellular Fluid Depletion, Hyponatremia With Normal Extracellular Fluid Volume, Hyponatremia With Excess Extracellular Fluid Volume
- Trial name
- NCT04402190
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Rotavirus Infection, Adenoviridae Infection
Study of Nitazoxanide Suspension in the Treatment of Diarrhea Caused by Enteric Viruses in Children
The purpose of this study is to determine the effect of nitazoxanide suspension in treating diarrhea caused by enteric viruses in children less than 12 years of age.
- Conditions
- Rotavirus Infection, Adenoviridae Infection, Norovirus Infection
- Trial name
- NCT00302640
- Testing
- Alinia (nitazoxanide)
- Volunteers
- 50 people
- Sponsor
- Romark Laboratories L.C.
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Osteoarthritis Knee Pain
A Study of Duloxetine in Patients With Osteoarthritis Knee Pain
The primary purpose of this study is to determine if duloxetine 60 mg once daily (QD) reduces pain severity in patients with osteoarthritis (OA) knee pain compared with placebo.
- Trial name
- NCT00945945
- Testing
- Duloxetine (DLX)
- Where
- 26 sites in United States, Germany and 6 more
- Volunteers
- 424 people
- Sponsor
- Eli Lilly and Company
Breast Implantation
Retrospective Study of Incidence and Etiology of Reoperation After Primary Augmentation With Natrelle® Breast Implants
Retrospective multi-center, post-marketing study to evaluate the incidence and etiology of reoperations with Allergan Natrelle® Breast Implants in primary augmentation (RANBI)
- Trial name
- RANBI (NCT02132572)
- Testing
- BIOCELL™ Textured 410 Implant
- Where
- 5 sites in France, Germany and 3 more
- Volunteers
- 201 people
- Sponsor
- Allergan
Angio-Oedema Caused by Angiotensin-Converting-Enzyme Inhibitor
Bradykinin-degradating Enzymes Activities in Angiotensin-Converting Enzyme Inhibitors-associated Angioedema
Angiotensin-Converting-Enzyme-inhibitors-dependent angioedema (ACEi-AE) is the most frequent form of bradykinin-mediated AE, with an estimated prevalence of 0.1% to 0.7%.
- Trial name
- KIN-ACE (NCT04763577)
- Testing
- Assay of Bradykinin-degradating enzymes.
- Where
- 4 sites in France
- Volunteers
- 243 people
- Sponsor
- University Hospital, Grenoble
Cerebral Palsy
The Changing Panorama in Risk Factors of Cerebral Palsy
The study will be carried of scanning the database of 296 individuals with cerebral palsy followed in the university pediatric rehabilitation clinic.
- Trial name
- NCT04716530
- Testing
- No intervention is associated with the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 296 people
- Sponsor
- Istanbul Medeniyet University
Diabetes, Type 1 Diabetes
Predictive and Protective Factors in the Cause of Diabetes - A Study in Twins
This study, conducted at St. Bartholomew's Hospital, London, England, will determine whether cells passed from mother to offspring during pregnancy increase or decrease the child's risk of developing type 1 diabetes.
- Trial name
- NCT00339781
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Secondary Hyperparathyroidism Due to Renal Causes
Efficacy and Safety of Paricalcitol in the Reduction of Secondary Hyperparathyroidism After Kidney Transplantation.
To demonstrate the superiority of paricalcitol treatment at early renal post-transplantation (M6) in the control of iPTH (Intact parathyroid hormone) compared to the use of vitamin D nutritional supplements (calcifediol) in…
- Trial name
- PARIDOINAL (NCT01939977)
- Testing
- Paricalcitol, Calcifediol
- Where
- 16 sites in Spain
- Volunteers
- 148 people
- Sponsor
- Fundación Senefro
Intracranial Aneurysms
Patients' Follow-up After Subarachnoid Haemorrhage Caused by Ruptured Intracranial Aneurysms
After endovascular treatment of the intracranial aneurysm, recanalization may occur, with a risk of recurrent subarachnoid haemorrhage or long-term angiographic recurrences of aneurysms.
- Trial name
- FUSAC (NCT02879175)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Neurogenic Urinary Bladder
Alfuzosin Treatment in Children and Adolescents With Neurogenic Urinary Bladder Dysfunction
The primary objective of the study was to evaluate the efficacy of Alfuzosin in comparison to Placebo on the detrusor Leak Point Pressure (LPP) in children and adolescents 2-16 years of age with elevated detrusor LPP of…
- Trial name
- ALFACHIN (NCT00549939)
- Testing
- Alfuzosin
- Where
- 18 sites in United States, Bulgaria and 16 more
- Volunteers
- 172 people
- Sponsor
- Sanofi
Osteomyelitis
Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
This is a research study designed to look at the efficacy and safety of daptomycin given at a dose of 6 mg/kg or 8 mg/kg in subjects being treated for prosthetic hip or knee infections caused by Staphylococci.
- Trial name
- NCT00428844
- Testing
- daptomycin, vancomycin, teicoplanin
- Where
- 26 sites in United States, Russia and 1 more
- Volunteers
- 75 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Head and Neck Cancer, Xerostomia
Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy
The goal of this clinical research study is to evaluate the safety and tolerability of injecting certain cells that you produce in your bone marrow called mesenchymal stem cells (MSCs) into your salivary glands.
- Trial name
- NCT05820711
- Testing
- MSC
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Wisconsin, Madison
Phlebitis
Peripheral Venous Catheter Trial: 3 Day Versus No Routine Change
The purpose of this study is to investigate the effects of extending the dwell time of peripheral intravenous cannulas on clinical outcomes and cost.
- Trial name
- NCT00103636
- Testing
- Extending peripheral intravenous (IV) cannula dwell times
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Royal Brisbane and Women's Hospital
Status Epilepticus
The Etiology of New-onset Status Epilepticus
This study will help to identify the causes of new epilepsy and provide a basis for the development of a rational and standardized diagnosis and treatment plan to reduce the rate of disability and death.
- Trial name
- NCT05647525
- Testing
- Perform autoimmune encephalitis titer tests
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jie Liu
Bicuspid Aortic Valve (BAV), Aortic Aneurysm
Research on Aneurysm Growth Prediction in Vascular Dilation Caused by Bicuspid Aortic Valve Based on VDM and CFD
Bicuspid aortic valve (BAV) is the most common congenital valvular malformation, characterized by heterogeneous phenotypic subtypes that predispose patients to secondary aortic pathologies, including valvular dysfunction and…
- Conditions
- Bicuspid Aortic Valve (BAV), Aortic Aneurysm, TAVR
- Trial name
- NCT07782918
- Testing
- Transcatheter Aortic Valve Replacement
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pleural Effusion, Malignant
The Value of PET-CT in Pleural Effusions
The investigators aim is to asses the diagnostic power of 18F-FDG PET-CT in discriminating malignant from nonmalignant causes in patients with a recurrent unilateral pleural effusion of unknown origin.
- Trial name
- NCT03272997
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Naestved Hospital
Macular Edema Secondary to Retinal Vein Occlusion
A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion)
Researchers are looking for a better way to treat people who have macular edema secondary to retinal vein occlusion (RVO). In people with RVO, a blood vessel that carries blood away from the retina (vein) becomes blocked.
- Trial name
- QUASAR (NCT05850520)
- Testing
- Aflibercept, VEGF Trap-Eye(Eylea, BAY86-5321)_higher dose, Aflibercept, VEGF Trap-Eye(Eylea, BAY86-5321)_2 mg, Fluorescein
- Where
- 273 sites in United States, Australia and 25 more
- Volunteers
- 892 people
- Sponsor
- Bayer
Sepsis, Cancer
Sepsis As a Cause of Death Among Elderly Cancer Patients
The goal of this retrospective study is to explore the association between sepsis and morality among the elderly cancer patients.
- Trial name
- NCT06619535
- Where
- Egypt
- Volunteers
- 5,239,194 people
- Sponsor
- asmaa salama ibrahim
Bilateral Hearing Loss for Causes Other Than Tumors
Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects
The purpose of this research study is to determine whether Auditory Brainstem Implant (ABI) can improve hearing in children who are deaf and cannot receive a cochlear implants.
- Trial name
- ABI (NCT01864291)
- Testing
- Nucleus 24 (discontinued) and ABI541 Auditory Brainstem Implants (ABI)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
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