Clinical trials: Aetiology
Exoskeleton Device, Sensory Disorder
Efficacy of Intensive Visual Simulation (IVS) Before Exoskeleton-assisted Step Training in Patients With Hemisensory Syndrome With Brain Injury of Vascular Etiology.
Clinical trial involving a medical device, not intended for CE marking, randomized, blinded to evaluate the efficacy of preparatory treatment with Intensive Visual Simulation 4 (IVS) prior to exoskeleton-assisted (EKSO) step…
- Conditions
- Exoskeleton Device, Sensory Disorder, Brain Injuries, Vascular
- Trial name
- IVS (NCT07860840)
- Testing
- Rehabilitation treatment with IVS before step training using an exoskeleton, Rehabilitation treatment with step training using an exoskeleton
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Urinary Tract Infections
Treatment of Extended Spectrum Betalactamase Producing Bacteria Causing Urinary Tract Infections in General Practice
The prevalence of extended spectrum beta-lactamase (ESBL) producing bacteria found in urine sample cultures has been increasing over the past decades.
- Trial name
- NCT01531023
- Where
- 7 sites in Norway
- Volunteers
- 168 people
- Sponsor
- University of Oslo
Hydrocephalus, Ventriculoperitoneal Shunt Malfunction
Comparison of Programmable and Non-programmable CSF Shunts Among Adult Hydrocephalus Patients With Different Etiologies
Programmable valve (PV) has been shown as a solution to the high revision rate in pediatric hydrocephalus patients, but it remains controversial among adults.
- Trial name
- NCT05534659
- Testing
- Programmable valve, Non-programmable valve
- Volunteers
- 325 people
- Sponsor
- Chang Gung Memorial Hospital
Radiation Induced Oral Mucositis
Appaconitine Patch for Oral Mucositis Pain Caused by Chemoradiotherapy in Patients With Nasopharyngeal Cancer
The purpose of this clinical study is to evaluate the efficacy of lappaconitine adhesive patch in alleviation radiation induced mucositis pain and the improvements in QOL of patients with nasopharyngeal carcinoma .
- Trial name
- NCT03518489
- Testing
- Lappaconitine Adhesive Patch, standard care
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Fujian Cancer Hospital
Coronavirus Disease 2019, Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Study of Varespladib in Patients Hospitalized With Severe COVID-19
This is a 2-part, multi-center, randomized, double-blind, placebo-controlled, phase 2 study designed to evaluate the safety, tolerability, and efficacy of oral varespladib, in addition to standard of care, in patients…
- Trial name
- STAIRS (NCT04969991)
- Testing
- Varespladib
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- Ophirex, Inc.
Acute Gastroenteritis, Vomiting
Infectious Etiology of Vomiting in Children With Presumed Acute Gastroenteritis
In children with acute gastroenteritis (AGE), vomiting often precedes diarrhea. To establish the diagnosis of AGE, enteropathogen detection typically relies on diarrheal stool samples.
- Trial name
- NCT05270291
- Testing
- rectal swab
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Medical University of Warsaw
COVID-19 Pandemic, Morality
Evaluation of Corticosteroids Use and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Study
Despite the recommendations to avoid using corticosteroids systematically for hospitalized coronavirus disease of 2019 (COVID-19) patients, healthcare professionals used personalized treatments, including corticosteroids, as…
- Trial name
- NCT05844410
- Testing
- Corticosteroid
- Where
- Lebanon
- Volunteers
- 422 people
- Sponsor
- Lebanese University
Infections Caused by Anaerobic Bacteria, Renal Impairment
Pharmacokinetics and Safety Study of Levornidazole Disodium Phosphate for Injection in Subjects With Renal Impairment and Normal Renal Impairment
To evaluate the pharmacokinetics and safety of a single intravenous dose of levornidazole disodium phosphate for injection in subjects with moderate and severe renal impairment and healthy subjects.
- Trial name
- NCT07033182
- Testing
- Levornidazole Disodium Phosphate for Injection
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Vitamin B12 Deficiency
Long-term Use of Proton Pump Inhibitors May Cause Vitamin B12 Deficiency in the Institutionalized Elderly
This study was designed to determine whether elderly residents of long term care facilitated who had been taking proton pump inhibitors (PPI) for more than 12 months were more likely to have vitamin B12 deficiency than residents…
- Trial name
- NCT00843453
- Testing
- blood collection, treatment (cyanocobalamin nasal spray)
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Macular Edema, Central Retinal Vein Occlusion
Comparison of Initial Ozurdex (Dexamethasone Implant) to Avastin (Bevacizumab) for Treatment of Macular Edema Caused by Central Retinal Vein Occlusion (CRVO)
The purpose of this study is to compare visual improvement and total number of intraocular injections in eyes with macular edema following central retinal vein occlusion (CRVO)after initial treatment with Ozurdex (dexamethasone…
- Trial name
- NCT01231633
- Testing
- Ozurdex, Avastin
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Long Island Vitreoretinal Consultants
Infertility, Intrauterine Adhesions
Treatment of Infertility by Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchyma Stem Cells
Study of the treatment of infertility caused by recurrent intrauterine adhesions (IUA) by collagen scaffold loaded with umbilical cord derived mesenchymal stem cells (UC-MSCs) to provide clinical evidence of safety and…
- Trial name
- NCT02313415
- Testing
- UC-MSCs therapy
- Where
- China
- Volunteers
- 26 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Bacteremia Due to Methicillin Susceptible Staphylococcus Aureus
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia
"Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia remains a major cause of community- or hospital-acquired bloodstream infections with an overall mortality estimated around 25%.
- Trial name
- CLOCEBA (NCT03248063)
- Testing
- Cloxacillin, Cefazolin
- Where
- France
- Volunteers
- 315 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sport Injury
Epidemiology of Injuries Caused by the Practice of Artificial Structure Climbing
This study aims to precisely describe epidemiology of injuries than occur during practice of climbing in artificial structure. Each participant will complete questionnaires in order to identify injuries.
- Trial name
- EPITRAUMABLOC (NCT05111587)
- Testing
- Questionnaire
- Where
- Reunion
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pneumonia
Etiology and Incidence Assessment of Radiographically-confirmed Community Acquired Pneumonia (CAP)
This is an epidemiological study to investigate the etiology of radiographically-confirmed community-acquired pneumonia (CAP) in adults aged ≥18 years.
- Trial name
- OSPIS (NCT03606135)
- Testing
- The Pneumonia Group, The Control Group
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Region Skane
Mycobacterium Infections, Nontuberculous
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
The primary objective of this study is to generate evidence demonstrating the domain specification (via modern psychometric methods), reliability, validity, and responsiveness (within-subject meaningful change) of the…
- Trial name
- ARISE (NCT04677543)
- Testing
- ALIS, Azithromycin, Ethambutol
- Where
- 62 sites in United States, Argentina and 10 more
- Volunteers
- 99 people
- Sponsor
- Insmed Incorporated
Influenza
Safety and Immunogenicity of Two Doses of a Tetravalent Influenza Vaccine in Adults Aged 18 Years and Above
Evaluate the immune response and reactogenicity of H5N1 vaccination in adults aged 18 years and above (as part of a tetravalent vaccine)
- Trial name
- NCT00620815
- Testing
- Pandemic influenza vaccine + seasonal influenza vaccine /pandemic influenza vaccine, Pandemic influenza vaccine + seasonal influenza vaccine / pandemic influenza vaccine
- Where
- 2 sites in Germany
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Bronchial Hemorrhage
Bronchial Injury Caused by Bronchial Cuff
Double lumen endotracheal tubes (DLT) are wildly used to maintain independent lung ventilation during thoracic surgery. Our aim is to assess whether the DLT bronchial cuff inflated or not is associated with tube displacement and…
- Trial name
- NCT05417295
- Testing
- Inflating air into the bronchial cuff before changing position, Inflating air into the bronchial cuff after changing position
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Neoplasm
Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls
The purpose of this research study is to understand if platelets in the blood become more active during cancer and specially advanced stages of cancer, in the future the investigators want to see if reducing platelet activity can…
- Trial name
- NCT02450175
- Testing
- Everolimus, Letrozole
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sinai Hospital of Baltimore
Chronic Pain
Increased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription Opioids
Managing pain in patients who abuse prescription opioids presents many challenges, including the development of opioid-induced hyperalgesia (OIH).
- Trial name
- NCT01821430
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Georgetown University
Haematochezia
Clinical Characteristics, Etiologies, and Outcomes of Patients With Haematochezia at Al-Rajhi University Hospital.
Haematochezia is the passage of bright red or maroon blood or blood clots from the rectum, usually originates from a source in lower parts of the gastrointestinal (GI) tract In addition, haematochezia can be seen in patients with…
- Trial name
- NCT07157228
- Volunteers
- 70 people
- Sponsor
- Assiut University
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