Clinical trials: Aetiology
Hypoparathyroidism
Hypoparathyroidism in Denmark
The purpose of this study is to identify the number of persons in Denmark with the diagnose hypoparathyroidism, autosomal dominant hypocalcaemia or pseudohypoparathyroidism.
- Trial name
- HypoPT (NCT01498341)
- Where
- Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anemia, Leukemia
Epoetin Alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy
RATIONALE: Drugs such as epoetin alfa may relieve anemia caused by chemotherapy. The best time for giving epoetin alfa during chemotherapy is not yet known.
- Conditions
- Anemia, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003341
- Testing
- epoetin alfa, quality-of-life assessment
- Where
- 18 sites in United States
- Volunteers
- 275 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Disorder Related to Transplantation, Virus Diseases
Replacement of Lamivudine by Telbivudine to Improve Renal Function
Nephrotoxicity is one of the adverse effects of lamivudine and dosage of lamivudine has to be reduced if patients' renal function is insufficiency. Telbivudine may improve glomerular filtration rate.
- Conditions
- Disorder Related to Transplantation, Virus Diseases, Injury Due to Exposure to External Cause
- Trial name
- NCT02447705
- Testing
- telbivudine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Exercise-Induced Muscle Damage, Rhabdomyolysis
DOES LOWER BODY PLYOMETRICS CAUSE RHABDOMYOLYSIS IN FEMALE VOLLEYBALL PLAYERS-AN EXPERIMENTAL STUDY
Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players.
- Conditions
- Exercise-Induced Muscle Damage, Rhabdomyolysis, Athletes
- Trial name
- NCT07352319
- Testing
- plyometric program
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Procalcitonin, Pneumonia
Procalcitonin Test for Differentiation of the Cause of Pneumonia
The purpose of this study is to evaluate the usefulness of procalcitonin test for differentiation of the cause of pneumonia in patients with cancer.
- Conditions
- Procalcitonin, Pneumonia, Cancer
- Trial name
- NCT03350802
- Testing
- procalcitonin test
- Where
- South Korea
- Volunteers
- 649 people
- Sponsor
- National Cancer Center, Korea
Small Fiber Neuropathy
Causes Associated With Small Fiber Neuropathy (SFN).
Small fiber neuropathy (SFN) is an injury of cutaneous nerve fibers, mainly by a decrease in their density within the cutaneous tissue.
- Trial name
- EtioNPF (NCT04170205)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Brest
Neurotoxicity, Unspecified Adult Solid Tumor, Protocol Specific
Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer
RATIONALE: Vitamin E may prevent peripheral neuropathy caused by chemotherapy in patients with cancer. It is not yet known whether vitamin E is more effective than a placebo in preventing peripheral neuropathy caused by…
- Trial name
- NCT00363129
- Testing
- vitamin E
- Where
- 69 sites in United States
- Volunteers
- 207 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Prosthetic Joint Infection, Staphylococcus
Clindamycin in Prosthetic Joint Infections Caused by Staphylococcus (CISTA)
The alternatives to the combination of Fluoroquinolone and Rifampicin in prosthetic joint infections (PJI) caused by staphylococcus are currently unclear.
- Trial name
- CISTA (NCT04946500)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anemia
The Impact of Red Packed Cells Transfusion on the Main Biological Markers to Determine the Etiology of Anemias
The aim of this work is to study the changes of key assays useful for the understanding of anemia mechanism before and after red packed cells transfusion: iron status, vitamin assays, hemolysis markers.
- Trial name
- BÉA/T (NCT01409967)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infection
Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter
RATIONALE: Giving the antibiotic teicoplanin by infusion and allowing bacteria to be exposed to the antibiotic for a longer period of time may be effective in preventing or controlling septicemia.
- Trial name
- NCT00024453
- Testing
- teicoplanin
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 1,360 people
- Sponsor
- Children's Cancer and Leukaemia Group
Deafness
False Positive Results in Newborn Hearing Screening
The purpose of this study is to investigate the rate of false-positive results in Newborn Universal Hearing Screening Programs and it´s possible causes.
- Trial name
- NHS (NCT00753194)
- Where
- Brazil
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Alzheimer Disease, Frontotemporal Degeneration (FTD)
PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia
Caregivers of individuals with Alzheimer's disease and related dementia rarely get the preparation or training they need to manage their caregiving responsibilities and to successfully balance their own self-care and their…
- Conditions
- Alzheimer Disease, Frontotemporal Degeneration (FTD), Lewy Body Dementia (LBD), Vascular Contributions to Cognitive Impairment and Dementia (VCID)
- Trial name
- NCT04748666
- Testing
- Problem Solving Training
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Irritable Bowel Syndrome
IBS Skin Patch Test Food Allergy Study
Participants with IBS are skin patch tested (no needles) to 80 different foods and food additives, compounded for patch testing, in search of food allergies. The testing requires 3 office visits within a 4 or 5 day period.
- Trial name
- NCT06288672
- Testing
- True avoidance diet
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- IBS-80, LLC
Acute Hypoxemic Respiratory Failure
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions
Background: There are no proven therapies specific for pulmonary dysfunction in patients with acute hypoxemic respiratory failure (AHRF) caused by infections (including Covid-19).
- Trial name
- DEXA-REFINE (NCT04545242)
- Testing
- Dexamethasone
- Where
- 40 sites in Spain
- Volunteers
- 980 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Autonomic Nervous System Disease, Amyloid Neuropathies
Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease
Transthyretin amyloidosis exhibits a variety of possible phenotypes, the hereditary neurological form being the most commonly found and studied (familial amyloidotic polyneuropathy or FAP), which can present from oligosymptomatic…
- Trial name
- NCT05087953
- Testing
- Head-Up Tilt table test, Heart Rate Variability
- Where
- 3 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
2019-nCoV
Clinical Study of Arbidol Hydrochloride Tablets in the Treatment of Pneumonia Caused by Novel Coronavirus
In the absence of 2019-ncov specific therapeutic drugs, arbidol is effective against a variety of coronaviruses in vitro pharmacodynamics.
- Trial name
- NCT04260594
- Testing
- Arbidol, basic treatment
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Jieming QU
Drop Foot
Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator
The goal of this clinical trial is to compare lidocaine without epinephrine to papaverine a known vasodilatory agent, in creating improved motor strength in patients with drop foot involving an entrapment of the Common Peroneal…
- Trial name
- NCT06637046
- Testing
- Diagnostic procedures, Lidocaine HCl
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephen Barrett
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a photoallergic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01119651
- Testing
- Tazarotene (Patch application in Challenge Phase)
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Anticoagulation
Excessive Warfarin Anticoagulation - Causes and Consequences
The aim of this study is to investigate the clinical significance of high INR (International Normalized Ratio) values (>9) in VKA (vitamin K antagonist) treated patients with atrial fibrillation.
- Trial name
- EWA (NCT02761941)
- Where
- Finland
- Volunteers
- 25,000 people
- Sponsor
- University of Turku
Helicobacter Pylori Infection, Susceptibility to
Helicobacter Pylori Infection Among Women With Recurrent Abortion of Unknown Cause
Helicobacter pylori (H. pylori) infection affects approximately one half of the world population and it is more prevalent in developing countries. This microorganism colonizes the stomach.
- Trial name
- NCT07293169
- Testing
- H pylori eradication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
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