Clinical trials: Age Problem
Problem of Aging, Smoking
Factors That Influence Adipose Derived Regenerative Cells' Yield and Viability
Human adipose tissue has been shown to contain a group of cells that possess extensive proliferative capacity and the ability to differentiate into multiple cell lineages.
- Conditions
- Problem of Aging, Smoking, Physical Activity, Gender
- Trial name
- NCT02651233
- Testing
- ADRCs therapy
- Volunteers
- 46 people
- Sponsor
- Clinical Centre of Serbia
Age Problem
Assessing the Precision of Convolutional Neural Networks for Dental Age Estimation From Panoramic Radiographs
The aim of this study is to assess the accuracy of a convolutional neural network in dental age estimation from digital panoramic radiographs. The reference standard will be the chronological age of the patient.
- Trial name
- NCT05901857
- Testing
- convolutional neural network
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Sedentary Lifestyle, Hyperinsulinemia
Developing a Physiological Understanding of High Duration Activity
When muscles are not contracting, the local energy demand by muscle and use of specific fuels used to produce energy by oxidative metabolism are minimal.
- Conditions
- Sedentary Lifestyle, Hyperinsulinemia, Glucose Tolerance Impaired, Low-density-lipoprotein-type
- Trial name
- NCT05135234
- Testing
- Muscular Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Metabolic Diseases, Aging Problems
Brain Substrate Switch to Ketones and Lactate
The brain is constantly active and energetically expensive, making up a quarter of the body's energy budget despite occupying only 2% of its mass.
- Trial name
- BSS (NCT06000605)
- Testing
- Fed, Fasted
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Acute Medical Problem
Outcomes of Patients Over 75 Years of Age Who Consulted the Emergency Department for a Medical Problem
The increasing activity of emergency departments, coupled with a decrease in the number of hospital beds, is leading to operational changes, of which the Short-Stay Unit (UHCD) is one example.
- Trial name
- GERIA-UH (NCT07302555)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Stroke, Problem of Aging
Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement
The purpose of this study is to find out if quercetin can increase blood levels of hypoxia-inducible transcription factor 1 (HIF-1 protein) and to see if there is a corresponding increase in blood flow to the brain.
- Trial name
- Quercetin (NCT01376011)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Aging Well, Aging Problems
Aquatic Exercise for Cognition and Mobility in Older Adults
The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.
- Conditions
- Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady
- Trial name
- NCT05501249
- Testing
- Aquatic Integrated Cognitive Motor Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emily Dunlap
Pain, Aging Problems
Efficiency of Facial Expression Diagnostic System in Pain Assessment After Geriatric Surgery
By integrating the methods used in the assessment of pain in geriatric surgery patients with literature, theory and research, this study aims to: evaluate the effectiveness of the facial diagnosis system in the evaluation of pain…
- Trial name
- NCT05756140
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Age Problem, Aortic Valve Disease
Frailty in Elderly Patients Receiving Surgical or Percutaneous Procedures for Valvular Disorders
In Italy, life expectancy at birth has reached 80 years in men and 85 in women; in about 50 years, life expectancy at the age of 80 has increased by an extraordinary 61% and 55%, respectively, due to more effective therapies and…
- Conditions
- Age Problem, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- FRASER-VD (NCT03365453)
- Testing
- frailty evaluation
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- University Hospital of Ferrara
Aging, Aging Problems
Development and Evaluation of a Psychological Intervention in Videogame Format for the Promotion of Active Aging
The social and health challenges of the aging population have led to the recommendation of active aging programs to increase the number of healthy and independent elderly people.
- Trial name
- GAMEPROAGING (NCT04982497)
- Testing
- Video game based intervention, Control group
- Where
- Spain
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Age Problem
Pathology of Helicases and Premature Aging: Study by Derivation of hiPS
Topic of this work is the involvement of replicative helicases in human premature ageing syndrome. Replicative helicases are ubiquitous and essential during numerous reactions of the DNA metabolism.
- Trial name
- HeliPS (NCT03898817)
- Testing
- taking of cutaneous cells
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Montpellier
Growth Hormone Disorder, Growth Hormone Deficiency in Children
Usability and Tolerability of the Norditropin NordiFlex® Injection Device in Children Never Previously Treated With Growth Hormone
This study is conducted in Europe. The purpose of this study is to assess the impact on daily life for children new to using a growth hormone injection device.
- Conditions
- Growth Hormone Disorder, Growth Hormone Deficiency in Children, Genetic Disorder, Turner Syndrome
- Trial name
- NCT01327924
- Testing
- Norditropin NordiFlex®
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Novo Nordisk A/S
Age Problem
Home Accidents Among Turkish Older Men and Women
Background: Home accidents are a significant public health issue in developed and developing countries. The present study aims to identify the factors associated with home accidents among older individuals in Türkiye.
- Trial name
- NCT06514872
- Testing
- prevalance and determinants of home accidents
- Where
- Turkey (Türkiye)
- Volunteers
- 8,225 people
- Sponsor
- Ataturk University
Foetal Growth Problem, Small for Gestational Age
Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
This study is conducted in Japan. The aim of this trial is to assess the efficacy and safety of somatropin in children born small for gestational age (SGA) in Japan.
- Trial name
- NCT00184717
- Testing
- somatropin
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Novo Nordisk A/S
Insulin Resistance, Age Problems
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.
This study intends to examine the effect of a commercially available nutritional supplement, Beta-hydroxy-beta-methylbutyrate(HMB) on whole-body responses to a sugar load.
- Trial name
- NCT03018496
- Testing
- Beta-Hydroxy-Beta-Methylbutyrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Coronary Syndrome, Age Problem
Determining the Age of First Acute Coronary Syndrome
The study aimed to evaluate the association between the obesity grade and the age of the first acute coronary syndrome (ACS). The effect of cardiovascular (CV) risk factors and the age of first ACS in patients with severe obesity…
- Conditions
- Acute Coronary Syndrome, Age Problem, Risk Factor, Cardiovascular
- Trial name
- NCT04578964
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Antalya Training and Research Hospital
Age Problem
Falls Risk Awareness Video Study
The primary aim of this study is to develop and evaluate three short corporate falls risk awareness videos of approximately 1-2 minutes (each) by using the feedback from community-dwelling people aged 50 years and above.
- Trial name
- NCT03154788
- Where
- Australia
- Volunteers
- 92 people
- Sponsor
- Curtin University
Transition-age Youth, Developmental Disabilities
Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
The purpose of this study is to determine the extent to which Project TEAM (Teens making Environment and Activity Modifications) is an effective, socially valid, and feasible intervention that prepares youth with developmental…
- Conditions
- Transition-age Youth, Developmental Disabilities, Cerebral Palsy, Autism
- Trial name
- ProjectTEAM (NCT02714868)
- Testing
- Project TEAM, Matched Comparison
- Volunteers
- 82 people
- Sponsor
- Boston University Charles River Campus
Anxiety, Anxiety Disorders
Randomized Feasibility Trial of Mind My Mind
In this feasibility RCT of the modular and flexible cognitive and behavioural therapy (Mind My Mind, MMM) compared with treatment as usual, the overall research aim was to explore the trial design and the acceptability of the…
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorder
- Trial name
- MindMyMind (NCT03448809)
- Testing
- Mind My Mind, TAU (Treatment as Usual)
- Volunteers
- 150 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Reading Problem
Computer Based Newsletter and Literacy Engagement of Middle-school Students
The purpose of this study is to improve motivation for reading by implementing a computer-based newsletter and examine the effects on the literacy engagement and reading achievement of middle school-aged students.
- Trial name
- NCT04511065
- Testing
- Newsletter using a virtual mode of delivery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo