Clinical trials: Age Related Cataract
Cataract, Age Related Macular Degeneration
Polarization Perception in Health and Disease. Testing a New Sight Test
A study to assess the utility of human polarization pattern perception for the detection, diagnosis and monitoring of eye disease
- Conditions
- Cataract, Age Related Macular Degeneration, Pseudophakia, Macular Disease
- Trial name
- TaNSiT (NCT03823092)
- Testing
- polarization sensitivity
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Warwickshire NHS Foundation Trust
Cataract, Macular Degeneration
S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000
RATIONALE: Aging may affect a person's vision. Vitamin E and/or selenium may help prevent cataracts or age-related macular degeneration in men receiving these drugs as part of a clinical trial for the prevention of prostate…
- Trial name
- SEE (NCT00784225)
- Testing
- selenium, vitamin E
- Where
- United States
- Volunteers
- 13,475 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Clinical Evaluation of Modified 2.2mm Microincision Phacoemulsification for Age-related Cataract
This study is a single-center, parallel-group, randomized controlled trial with the following objectives: to compare the incidence of post-operative descemet membrane detachment (DMD) in phacoemulsification surgery between…
- Trial name
- NCT04014699
- Testing
- modified 2.2mm microincision, conventional 2.2mm microincision
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)
The Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) is a 13-year study designed primarily to evaluate the safety and efficacy of a vitamin-mineral supplement (Centrum)…
- Trial name
- CTNS (NCT00309387)
- Testing
- Centrum
- Where
- Italy
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract, Age Related Macular Degeneration
Cataract and AMD in a Trial of a Multivitamin and Cocoa Extract
COSMOS-Eye is an ancillary study of the COcoa-Supplement and Multivitamins Outcomes Study (COSMOS; NCT02422745). COSMOS is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols…
- Trial name
- COSMOS-Eye (NCT03205202)
- Testing
- Cocoa extract, Multivitamin
- Volunteers
- 21,442 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dry Eye Syndromes, Cataract
Quality of Life and Visual Acuity of Visglyc Eye Drops on Dry Eye Patients
Clinical trial with medical devices, post-authorization, parallel, single-blind, randomized, comparative, prospective to study how afects the quality of life the use of ocular eye drops on patients with dry eye symptomatology and…
- Trial name
- NCT04063644
- Testing
- Vis Glyc Neo, Physiological saline solution
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- OPKO Health, Inc.
Cataract, Dry Eye Syndromes
Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA
The purpose of the study is to assess whether PROKERA can sufficiently stabilize the ocular surface prior to cataract surgery and improve post operative outcomes patients with moderate to severe dry disease.
- Conditions
- Cataract, Dry Eye Syndromes, Cataract Senile, Dry Eye
- Trial name
- NCT05148507
- Testing
- PROKERA
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Jeff Wongskhaluang
Cataract, Glaucoma
Village-Integrated Eye Worker Trial II - Pilot
The vast majority of blindness is avoidable. The World Health Organization (WHO) estimates that 80% of cases of visual impairment could be prevented or reversed with early diagnosis and treatment.
- Conditions
- Cataract, Glaucoma, Age Related Macular Degeneration, Diabetic Retinopathy
- Trial name
- VIEW II Pilot (NCT03278587)
- Testing
- Community-based screening program, Cataract camp program, Community health worker program
- Where
- Nepal
- Volunteers
- 87,992 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cataract
Outcomes of Phacoemulsification With Torsional Ultrasound
To determine the differences in intra-operative complications, surgical duration, fluid usage, corneal thickness and endothelium cell density in eyes undergoing microcoaxial phacoemulsification (MCP) either with Torsional or…
- Trial name
- NCT01010490
- Testing
- Torsional ultrasound (INFINITI, Alcon, USA), Longitudinal U/S (Infiniti system, Alcon, USA), Longitudinal U/S (LEGACY 20000, Alcon, USA)
- Where
- India
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Age-Related Cataract
The Application of Lens Dysfunction Index (DLI) in the Timing of Age-related Cataract Surgery
Before cataract surgery, subjects in the observation group used iTrace ocular aberration analyzer（itracey Technologies）and IOL-Master 700 biometer to measure the preoperative DLI(Dysfunctional lens index) and SS-OCT image of the…
- Trial name
- NCT04711395
- Testing
- measure the preoperative DLI、 SS-OCT image of the lens,、take photos of the anterior segment and self-scoring of the preoperative visual quality assessment scale.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Macular Degeneration, Cataract
Randomized Trials of Vitamin Supplements and Eye Disease
To determine whether vitamin E supplementation reduces the risk of cataract and age-related macular degeneration (AMD) in women. To determine whether vitamin C supplementation reduces the risk of cataract and AMD in women.
- Trial name
- NCT00000161
- Testing
- Aspirin, Beta-Carotene, Vitamin C
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract Senile
Venturi and Peristaltic Based Phacoemulsification in Femtosecond Laser Cataract Surgery
This study will compare two methods of vacuum (peristaltic or venturi) commonly used during the removal of a femtosecond treated cataract.
- Trial name
- NCT03970525
- Testing
- Venturi pump, Peristaltic vacuum pump
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wendell Scott
Cataract Senile, Endophthalmitis
Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Comparative safety study of intracameral levofloxacin versus moxifloxacin for postoperative infection prophylaxis
- Conditions
- Cataract Senile, Endophthalmitis, Antibiotic Side Effect, Safety Issues
- Trial name
- NCT04403334
- Testing
- Levofloxacin Ophthalmic, Moxifloxacin Ophthalmic
- Where
- Philippines
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Peregrine Eye and Laser Institute
Dementia, Mild Cognitive Impairment
Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Cataract Senile, Cataract
- Trial name
- NCT04047485
- Testing
- Visual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia