Clinical trials: Age Related Cataracts
Cataract Senile
Comparison Between Two Ss-OCT Biometry
Since recently a second swept-source optical coherence tomography (ss-OCT) optical biometry device was launched (Anterion, Heidelberg Engineering).
- Trial name
- NCT04333056
- Testing
- Biometric measurement agreement
- Where
- Austria
- Volunteers
- 210 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Age Related Cataract, Pain Management During Cataract Surgery
Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery
This study aims to evaluate the efficacy, safety, and potential mechanisms of prednisolone acetate eye drops for pain management in patients undergoing second-eye surgery for age-related cataracts.
- Trial name
- NCT06614348
- Testing
- Prednisolone acetate eye drop group, Sodium hyaluronate eye drops
- Volunteers
- 70 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Dry Eye Disease, Meibomian Gland Dysfunction
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction
This prospective study will investigate the effect of pre-operative Systane iLux system administration in treated cataract induced dry eye disease.
- Conditions
- Dry Eye Disease, Meibomian Gland Dysfunction, Cataract Senile, Dry Eye Syndromes
- Trial name
- NCT06483750
- Testing
- Systane iLux Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Washington University
Cataract Senile
Repeatability in Measurements of Two ssOCT and One OLCR Biometer
Achieving high accuracy and precision in ocular biometry has become primordial for cataract surgery, due to the shift of cataract surgery from a rehabilitation procedure to a refractive one.
- Trial name
- NCT04255706
- Testing
- biometric measurement IOLMaster 700, biometric measurement Lenstar LS 700, biometric measurement Anterion Heildelberg
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Cataract, Macular Degeneration Advanced
Cataract Surgery on Advanced Age Related Macular Degeneration Patients
The degree at which cataract surgery improves visual function in patients with advanced age-related macular degeneration (Advanced AMD) has been an on-going topic of discussion.
- Trial name
- NCT04045704
- Testing
- Cataract Surgery
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Cataract Senile
Evaluation of a Trifocal Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04545671
- Testing
- trifocal lens
- Where
- Germany
- Volunteers
- 389 people
- Sponsor
- Carl Zeiss Meditec AG
Age-related Cataract
Effective Lens Position After Cataract Surgery
Cataract patients were implanted with different types of intraocular lenses for grouping. SSOCT scanning was used to measure ELP and optometry.
- Trial name
- NCT04443101
- Testing
- different types of intracular lens
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Wenzhou Medical University
Age Related Cataracts, Cystoid Macular Edema
Evaluation of Central Macular Thickness in Femtosecond Laser-assisted Cataract Surgery
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure.
- Trial name
- FLAME (NCT03465124)
- Testing
- Femtosecond Laser, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Dementia, Mild Cognitive Impairment
Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
The study intends to measure the evolution over time of the cognitive capacity of patients undergoing cataract surgery in relation to the opaque lens removal surgery (cataract) in a population considered to be at risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Cataract Senile, Cataract
- Trial name
- NCT04047485
- Testing
- Visual Acuity, CAM (Confusion Assesment Method), CATQUEST 9-SF
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dry Eye Syndromes, Cataract
Quality of Life and Visual Acuity of Visglyc Eye Drops on Dry Eye Patients
Clinical trial with medical devices, post-authorization, parallel, single-blind, randomized, comparative, prospective to study how afects the quality of life the use of ocular eye drops on patients with dry eye symptomatology and…
- Trial name
- NCT04063644
- Testing
- Vis Glyc Neo, Physiological saline solution
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- OPKO Health, Inc.
Cataract, Phacoemulsification
Comparison of Manual Super Small Incision Cataract Surgery and Phacoemulsification
The purpose of this study is to compare the safety and efficacy of manual super small incision cataract surgery (MSSICS) and Phacoemulsification.
- Trial name
- NCT01146964
- Testing
- MSSICS, Phacoemulsification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Age-related Cataract
EDOF vs Enhanced vs Monofocal IOLs After Bilateral Cataract Surgery
Consecutive comparative case series evaluating visual outcomes and patientreported satisfaction after bilateral cataract surgery with implantation of the same IOL type (standard monofocal, enhanced monofocal, or novel EDOF IOL).
- Trial name
- NCT07548294
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Sakarya Yenikent State Hospital
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Age Related Cataracts, Pseudoexfoliation Syndrome
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons.
- Trial name
- NCT06053554
- Testing
- Phakoemulsification, Ziemer Z8 Femtolaser, Kowa Avansee Preset
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Age Related Cataract, Cataract
Effect of Trypan Blue on Corneal Endothelial Cell Count During Phacoemulsification
This randomized controlled trial evaluated the effect of trypan blue on corneal endothelial cell count in patients undergoing phacoemulsification for age-related cataract.
- Trial name
- NCT07735000
- Testing
- Trypan Blue, Phacoemulcification
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Age Related Cataracts
Release of Proinflammatory Cytokines (IL-1β, IL-6) and Total-prostaglandin (PG) Following Femtosecond Laser-assisted Cataract Surgery Compared to Manual Cataract Surgery
Patients with bilateral age related cataract will be included in the study. Manual cataract surgery (MCS) will be performed in one eye and laser cataract surgery (LCS) in the corresponding eye.
- Trial name
- NCT03390361
- Testing
- Femtosecond Laser-assisted, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cataract
Evaluation of the Aspheric ReSTOR IOL After Routine Cataract Extraction
The purpose of this study is to evaluate the visual outcomes and patient satisfaction after bilateral implantation of the aspheric ReSTOR multifocal intraocular lens (IOL) and compare it to a historical control group of patients…
- Trial name
- NCT00720005
- Testing
- Aspheric Acrysof ReSTOR intraocular lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Age-related Cataract
Evaluation of Capsular Bag Shape Changes After Plate-haptic Intraocular Lens Implantation by SS-OCT
Evaluation of capsular bag shape changes after plate-haptic intraocular lens implantation by SS-OCT.
- Trial name
- NCT05148741
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University