Clinical trials: Aged, 80 and Over
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Venous Insufficiency, CVI, Radiofrequency Ablation
Risks and Benefits of Radiofrequency Ablation for Chronic Venous Insufficiency (CEAP C3-C6) in Patients Aged 80 and Over
The prevalence of severe chronic venous insufficiency (CVI) is significant in the growing octogenarian population. While radiofrequency ablation (RFA) is a standard minimally invasive treatment, robust data on its outcomes and…
- Conditions
- Chronic Venous Insufficiency, CVI, Radiofrequency Ablation, Octogenarians(Aged 80 and Over), Cohort Study
- Trial name
- NCT07233616
- Testing
- Endovenous Radiofrequency Ablation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Depression
Preventing the Return of Depression in Elderly Patients
The purpose of this study is to compare the effectiveness of two doses of nortriptyline in elderly patients whose depression returned after stopping treatment. Nortriptyline is an antidepressant.
- Trial name
- NCT00000377
- Testing
- Nortriptyline
- Sponsor
- University of Pittsburgh
Aged, 80 and Over
Predictors Associated With Maintaining Driving in Old Age
The goal of this observational study is to learn about predictors associated with maintaining driving in old age. The main questions it aims to answer are : which and how medical factors can influence stopping or maintaining…
- Trial name
- NCT05872490
- Testing
- Semi-structured interviews, Questionnaire
- Where
- 3 sites in France
- Volunteers
- 657 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Aged, Nursing Homes
International Normalised Ratio Evaluation by Generalist Practitioners in Full-time Care Establishments for the Elderly
The main objective of this study is to evaluate, for a 6-month observation period, the concordance in terms of clinical decision making concerning therapeutic adjustment as determined by a weekly capillary International…
- Trial name
- INR-Cap pilote (NCT02614573)
- Testing
- CoagucheckXSR Capillary INR measures
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Accidental Fall, Accident Prevention
Effect of Treadmill Perturbation Training on Falls
This parallel, randomized, controlled trial aims to quantify the effects of slip- and trip-perturbation training on fall rates collected over 12 months, compared to time-matched treadmill walking, among community-dwelling older…
- Trial name
- NCT04733222
- Testing
- Perturbation training, Treadmill walking
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Heart Failure, Coronary Disease
Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older Adults
Care coordination, disease management, geriatric care management, and preventive programs for chronically ill older adults vary in design and their impact on long-term health outcomes is not well established.
- Conditions
- Heart Failure, Coronary Disease, Diabetes Mellitus, Asthma
- Trial name
- NCT01071967
- Testing
- Community-based nurse care management
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Health Quality Partners
Intensive Care (ICU), Age Over 80 Years
Pre-ICU Hospital Length of Stay and 30-day Mortality in the Very Old: a National Cohort of 315 042 ICU Admissions
How does waiting in hospital before intensive care affect older patients?Patients who become seriously ill are sometimes admitted to a regular hospital ward first, and only transferred to the intensive care unit (ICU) when their…
- Conditions
- Intensive Care (ICU), Age Over 80 Years, Hospital Length of Stay, Mortality
- Trial name
- NCT07571213
- Testing
- Time in hospital before ICU admission.
- Where
- Sweden
- Volunteers
- 315,042 people
- Sponsor
- Uppsala University
Polypharmacy, Adverse Drug Reaction
Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients
The purpose of this study is to determine whether an educational intervention given towards health care providers working in primary health care centers can reduce inappropriate prescribing in the elderly patient and thus reduce…
- Trial name
- NCT01732302
- Testing
- Educational intervention
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Karolinska Institutet
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Accidental Falls
A Feasibility Study of a Mobile Application Intervention to Promote Strength and Balance Exercises in Older People
This five arm feasibility study aims to promote self-management in strength and balance exercises among community-living older people.
- Trial name
- NCT02916849
- Testing
- Safe Step, OEP
- Where
- Sweden
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Umeå University
Dementia, Cognition Disorders in Old Age
Neuropsychological Assessment Of The Oldest-Old Population.(NEUROPSIC-GR)
Neuropsychological tests currently considered to evaluate the cognitive performance of the oldest-old population (more than 80 years) are not adapted to this group population.
- Trial name
- NEUROPSIC-GR (NCT05481749)
- Where
- 6 sites in Spain
- Volunteers
- 113 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Endothelial Dysfunction, Aging
Passive Mobilization and Vascular Function
With aging, vascular function (VF) declines. Inactivity and sedentary life style have been shown to contribute to the worsening of VF.
- Conditions
- Endothelial Dysfunction, Aging, Bed Rest
- Trial name
- NCT03087643
- Testing
- Passive mobilization - PM
- Where
- 3 sites in Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Colorectal Cancer, Chemotherapy
Supportive Cancer Care Networkers (SCAN)
Aim of the study is to increase the proportion of indicated patients with colorectal cancer undergoing adjuvant chemotherapy following surgical resection through an optimized symptom management and logistical support.
- Trial name
- SCAN (NCT01651832)
- Testing
- SCAN
- Where
- 9 sites in Germany
- Volunteers
- 261 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Healthy
Does Motor Imagery Training Enhance Control of Movement in Older Adults?
The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is: Will imagining a task improve control of force…
- Trial name
- NCT05669131
- Testing
- Motor imagery training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alzheimer Disease, Aging
Vanderbilt Memory and Aging Project
This study will use an observational cohort to cross-sectionally and longitudinally relate vascular health to clinical, imaging, and biological markers of early Alzheimer's disease and cerebrovascular disease among aging adults.
- Conditions
- Alzheimer Disease, Aging, Aged, 80 and Over, Biomarkers
- Trial name
- VMAP (NCT05372159)
- Testing
- none, observational study
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt University Medical Center
Malnutrition
Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.
The purpose of this study is to evaluate the effects of nutritional therapy in elderly malnourished patients. The hypothesises are that nutritional supplementation and dietary advice alone or in combination affects mortality…
- Trial name
- NCT01057914
- Testing
- Nutritional supplementation with a liquid formula, Dietary advice, Combination of supplement and dietary advice
- Where
- 5 sites in Sweden
- Volunteers
- 671 people
- Sponsor
- Uppsala University
Anesthesia
Oldest-old Patients Anesthesia in Orthopedic Surgeries
Average life span, life expectancy, and the number of older people, aged 65 years and over, have increased during the last decades.
- Trial name
- NCT06522178
- Testing
- Patient' ages
- Where
- Turkey (Türkiye)
- Volunteers
- 1,356 people
- Sponsor
- Istanbul Medeniyet University