Clinical trials: Aged Skin
Skin Aging, Facial Aging
Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality
This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis.
- Conditions
- Skin Aging, Facial Aging, Skin Quality
- Trial name
- NCT07466953
- Testing
- Mesenchymal Stem Cell-Derived Exosome
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mert Ersan
Skin Aging
A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging, by Comparing to a Placebo
A clinical study with approximately 15 subjects, aged 35-65 years of age, who must have crow's feet and at least one other type of facial fine lines/wrinkles in order to evaluate the efficacy of Activated Silk™ 27P-α to improve…
- Trial name
- NCT06804772
- Testing
- Investigational Facial Serum #3, Investigational Facial Serum #1, Investigational Facial Serum #2
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Victoria Collotta
Chronic Spontaneous Urticaria
24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up
The purpose of this trial is: 1. to assess the efficacy, pharmacokinetics, and safety of remibrutinib vs. placebo in adolescents from 12 to < 18 years of age suffering from chronic spontaneous urticaria inadequately controlled by…
- Trial name
- NCT05677451
- Testing
- LOU064 (blinded)
- Where
- 49 sites in United States, Argentina and 15 more
- Volunteers
- 100 people
- Sponsor
- Novartis Pharmaceuticals
Scabies
Comparison of Permethrin and Ivermectin in Children Greater Than 6 Yrs Age for Treatment of Scabies
Scabies is highly contagious,pruritic infestation of skin.Various treatment modalities have been used but search for ideal scabicide is ongoing.we wnt to coduct this study to compare the outcome of permethrin verses ivermectin in…
- Trial name
- not existed (NCT06896929)
- Testing
- Permethrin Cream, 5%, Ivermectin 200 µg/kg
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Skin Aging, Cheek Wrinkles
TCRM for Correction of Cheek Including Fine Lines
The purpose of this clinical study is to evaluate benefits and risks of injecting TCRM in the cheek including fine lines. The goal is to show that treatment with TCRM will result in correcting the cheek area including the fine…
- Trial name
- NCT07145905
- Testing
- TCRM
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Breast Cancer
English Mammography Screening Outcomes by Age, Frequency and Test Threshold
Breast cancer screening involves taking mammograms (x-rays) of women's breasts to search for signs of cancer. This study investigates the impact of test threshold, screening interval (frequency) and age of eligibility on…
- Trial name
- ATHENA-M (NCT05247463)
- Testing
- Increase in upper age of eligibility for breast cancer screening from 64 to 70, Screening round length, Screening test threshold
- Where
- United Kingdom
- Volunteers
- 10,000,000 people
- Sponsor
- University of Warwick
Rheumatic Diseases
Patient Self-administration of Cortisol for Cortisol-responding Disorders in Men and Women Over the Age of 17
Participants diagnosed as having fibromyalgia, osteoarthritis, and rheumatoid arthritis are to be brought to a minimum symptom state using a 3-week period during which they are to ingest modest doses of cortisol tablets with…
- Trial name
- NCT03558971
- Testing
- Cortisol
- Where
- United States
- Volunteers
- 2,430 people
- Sponsor
- Helen Foundation
Systemic Lupus Erythematosus
A Study to Investigate Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Systemic Lupus Erythematosus
The purpose of this study is to characterize the pharmacokinetics (PK), pharmacodynamics (PD), and safety of subcutaneous (SC) anifrolumab in pediatric participants with moderate to severe systemic lupus erythematosus (SLE) while…
- Trial name
- NCT07630714
- Testing
- Anifrolumab + APFS
- Where
- 39 sites in Australia, Belgium and 8 more
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Metabolic Syndrome, Obesity
Mobile Health (M-health) Intervention to Reduce the Epigenetic Signature in Metabolic Syndrome (MetS)
The goal of this interventional study is to learn about the improvement in body composition effects of lifestyle intervention in subjects with metabolic syndrome.
- Trial name
- NCT06448806
- Testing
- mobile health lifestyle intervention
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Breast Cancer
Survival of BCS vs Mx in Asymptomatic Screen-detected NPBC
We performed this study on a consecutive cohort of women with asymptomatic screen-detected NPBC. The clinicopathological characteristics, 10-year relapse-free survival (RFS) and overall survival (OS) were compared between BCS and…
- Trial name
- NCT06103032
- Testing
- Breast Conserving Surgery, Mastectomy
- Where
- China
- Volunteers
- 1,020 people
- Sponsor
- Peking Union Medical College Hospital
Skin Ageing
Effect of Pomanox® on Skin Ageing (POMASKIN)
The state of skin health impacts not only on the general health of individuals, but also on mental health. Ultraviolet radiation (UV) is one of the main external factors that causes skin ageing, producing photo-aging…
- Trial name
- POMASKIN (NCT05842447)
- Testing
- 367 mg Pomanox group, 700 mg Pomanox group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Systemic Lupus Erythematosus
Immunogenicity and Safety of HPV Vaccine Gardasil in Young Women
The purpose of this study is to evaluate the immunogenicity and safety of the HPV vaccine Gardasil in young women.
- Trial name
- NCT00786409
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Chicago
Atopic Dermatitis
Efficacy of Topical Coal Tar in Children With Atopic Dermatitis
Rationale/hypothesis: Atopic dermatitis (AD) is an inflammatory skin disease, occurring most frequently in children. Currently, topically applied corticosteroids are used as a standard anti-inflammatory treatment.
- Trial name
- NCT03461302
- Testing
- Topical coal tar, Topical corticosteroids
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Radboud University Medical Center
Acute Bacterial Skin and Skin Structure Infections
A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)
This study will evaluate the safety, tolerability, and efficacy of tedizolid phosphate (MK-1986) compared with comparator antibacterial agent in participants from birth to less than 12 years of age with acute bacterial skin and…
- Trial name
- NCT03176134
- Testing
- Tedizolid phosphate, Comparator
- Where
- 58 sites in United States, Brazil and 12 more
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Allergic Rhinoconjunctivitis, Chronic Urticaria
Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU)
The conduct of this clinical trial is aimed at determining the most suitable dose regimen for children in different age groups, and secondarily to assess the safety and tolerability of bilastine in this paediatric population…
- Trial name
- NCT01081574
- Testing
- Bilastine
- Where
- 7 sites in Australia, Germany and 1 more
- Volunteers
- 36 people
- Sponsor
- Faes Farma, S.A.
Pressure Ulcers
Increasing Fluids in Older Adults to Prevent & Treat Pressure Ulcers
The purpose of this study is to determine whether providing extra fluid to nursing home residents will help prevent or heal pressure ulcers.
- Trial name
- NCT00507650
- Testing
- Fluid intervention, Fluid intervention plus 10 ml/kg/day
- Volunteers
- 63 people
- Sponsor
- University of California, San Francisco
Xerosis Cutis
Comparison of 12% Ammonium Lactate and 10% Urea Cream in Geriatric With Xerosis Cutis
This study aims to compare the efficacy and safety between moisturizing cream containing 12% ammonium lactate and 10% urea in geriatric with xerosis cutis.
- Trial name
- NCT04127513
- Testing
- Ammonium Lactate, Urea
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Breast Cancer Female
Pre-Operative Window of ET to Inform RT Decisions (POWER II)
This is a Phase III, multisite exploratory study for women ≥ 65 years of age with early stage estrogen receptor positive (ER+) breast cancer.
- Trial name
- POWER II (NCT06507618)
- Testing
- Tamoxifen, Letrozole, Anastrozole, or Exemestane
- Where
- 6 sites in United States
- Volunteers
- 354 people
- Sponsor
- University of Virginia
Hereditary Angioedema (HAE)
CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12
The objectives of this study were to evaluate: (1) the dose response and (2) the pharmacokinetics (PK) and pharmacodynamics (PD) of intravenous (IV) administration of CINRYZE for the treatment of acute angioedema attacks in…
- Trial name
- NCT01095510
- Testing
- CINRYZE
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 9 people
- Sponsor
- Shire
Breast Cancer, Parenting Anxiety
Development and Application of a Parenting Anxiety Intervention Program for Young and Middle-Aged Female Breast Cancer Patients
This feasibility study aims to develop and test an intervention program for young and middle-aged female breast cancer patients who experience parenting concerns.
- Trial name
- NCT07331740
- Testing
- Parenting Concerns Support Program
- Volunteers
- 20 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine