Clinical trials: Aging, Healthy
Preventive Intervention
Preventive Intervention to Promote Healthy Ageing
The aim of the project is the support of healthy ageing of older adults in acommunity. Efficient educational and psychosocial intervention will besuggested and verified to prevent anxiety, depression, and cognitivedisorders of…
- Trial name
- NCT05637177
- Testing
- Anging Wisely, Music therapy, Reminiscence therapy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Healthy, Aging
Brain Blood Flow: Age and Gender
Baseline cerebral blood flow through the middle cerebral artery (MCA) and cerebral vasodilator response of the MCA to inhaled carbon dioxide (CO2) will be measured in young women, young men, older women, and older men using…
- Trial name
- NCT02840851
- Testing
- MRI, TCD
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Older Adults, Aging Well
Self-Adaptive Immersive Virtual Reality Serious Game to Enhance Motor Skill Learning and Attention in Older Adults
While scientific evidence emphasizes the detrimental effect of sedentary behavior on health, the literature suggests that, on average, older adults spend 75% of their days in a sedentary manner, and often isolated (Petrusevski…
- Conditions
- Older Adults, Aging Well, Aging
- Trial name
- SAVinGs (NCT06141642)
- Testing
- Self-adaptive serious game, Non-adaptive serious game
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Laval University
Healthy
Impact of Aging on Cytokine Production by Innate Immune Cells
The main goal of this study is to investigate the impact of aging on the responsiveness of peripheral blood immune cells. To this aim, the investigators will take advantage of a recently described syringe-based assay system that…
- Trial name
- Cytokinage (NCT02660723)
- Testing
- Healthy Volunteers
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
MS-ResearchBiomarkerS
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MS-ReBS (NCT05204459)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Sarcopenia, Healthy Elderly
Exercise and Nutritional Supplementation
To understand the effects of a novel dietary supplement when used in conjunction with a healthy lifestyle exercise program and to define biomarkers that are specific to sarcopenia.
- Conditions
- Sarcopenia, Healthy Elderly, Healthy Young
- Trial name
- ENSASL (NCT03536871)
- Testing
- multi-nutrient supplement, Exercise
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging
Mind-body Interventions for Healthy Aging
The goal of this study is to examine the impact of mind-body interventions in enhancing behavioral and neural correlates of attentional control in older adults.
- Trial name
- HealthyAgers (NCT03626532)
- Testing
- Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Ageing, Aerobic Exercise
Acute Exercise Effects on Arterial Stiffness and Cardiovagal Modulation in Adults
Background and Gap: The physiological importance of large artery distensibility in cardiovascular function is well-established. Stiffening of central arteries leads to elevated systolic blood pressure (SBP), increased left…
- Conditions
- Ageing, Aerobic Exercise, Resistance Exercise, Combined Exercise
- Trial name
- PUMPING ARTERY (NCT06616428)
- Testing
- Bike group fitness class, Pump Power, Global Training
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Radiation Tolerance, Skin Aging
Skin Safety Profile of Different Exposure to the Light Emitting Diode (LED) in Healthy Subjects
Photomodulation is a process which manipulates or regulates cell activity using light sources without thermal effect. Different studies have investigated the use of non-thermal low dose light emitting diode (LED) array for…
- Conditions
- Radiation Tolerance, Skin Aging, Rhytids
- Trial name
- NCT00818311
- Testing
- LED GentleWaves®
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Healthy Aging
Frenkel Exercises in Geriatric Balance and Fall Prevention
Aging is a natural process starting from birth and progressing through childhood and adulthood, marked by physical and mental decline, including musculoskeletal, cognitive, and motor deterioration.
- Trial name
- NCT06990828
- Testing
- Frenkel Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Okan University
Vascular Aging
Vascular Aging and Lp299v Study in Healthy Adults
Emerging data suggest the gut microbiota regulates multiple mechanisms related to vascular aging, but no intervention targeting the gut microbiota has been tested in older adults without cardiovascular risk factors or…
- Trial name
- NCT05296395
- Testing
- Lactobacillus Plantarum 299v in fermented oat drink
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Dignity, Old Age; Debility
INNOVATEDIGNITY: Co-designing Digital Health Technologies With Older People in Homecare Settings.
One of the crucial components of successful ageing is to live independently in old age. Yet in UK alone, nearly 300000 older people require assistance with 3 or more essential daily tasks like eating, bathing and mobility which…
- Conditions
- Dignity, Old Age; Debility, Healthy Aging, Digital Technology
- Trial name
- NCT04884711
- Testing
- No Interventions. Participants will be using their everyday digital health technologies., In depth Interviews, Focus Group Discussions
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Brighton
Healthy Aging
Evaluating the Neurocomputational Mechanisms of Explore-Exploit Decision Making in Older Adults
The full experiment involves participants coming into the lab on five separate occasions for neuropsychological testing, a decision making battery, functional and structural MRI, and two TMS sessions for stimulation of the target…
- Trial name
- NCT05178381
- Testing
- Continuous theta burst transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Mobility Limitation
BAILA: Being Active, Increasing Latinos Healthy Aging
Investigators propose a randomized controlled trial (RCT) to test the efficacy of the revised 4-month BAILAMOS© program for improving lifestyle PA and health outcomes (physical and cognitive function, self-reported functional…
- Trial name
- BAILA (NCT01988233)
- Testing
- BAILAMOS© Dance Program, Health Education Control Group
- Where
- 12 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Aging
A Study to Evaluate Efficacy of Dietary Ingredient in Vitality and Metabolic Factors in Healthy Individuals
The present study is a randomized, placebo-controlled, feasibility study to evaluate efficacy of dietary ingredients in vitality \& metabolic factors in healthy individuals.
- Trial name
- NCT06188949
- Testing
- Dolichos biflorus (Horsegram) seed extract, Carica papaya leaves extract
- Where
- 2 sites in India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Aging, Health Promotion
Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults
This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults.
- Conditions
- Aging, Health Promotion, Mental Health
- Trial name
- NCT07540117
- Testing
- Mindfulness Meditation and Walking-Pole Exercise
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Sarcopenia
Neuromuscular Electrical Stimulation (NMES) and Muscle Protein Accretion (ES-PRO)
In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES will be studied.
- Trial name
- ES-PRO (NCT01615276)
- Testing
- Enraf Nonius Tensmed S84 for Neuromuscular electrical stimulation (NMES), No Enraf Nonius Tensmed S84 for Neuromuscular electrical stimulation (NMES) NMES
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Aging, Healthy
ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly
The purpose of the ACTIVE study was to test if cognitive training interventions could maintain functional independence in elders by improving basic mental abilities, with follow-up assessments through five years.
- Trial name
- ACTIVE (NCT00298558)
- Testing
- Cognitive Training
- Where
- 7 sites in United States
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Sedentary Lifestyle
Sedentary Behavior Interrupted Randomized Controlled Trial (P2)
Epidemiological findings indicate that older adults do not meet physical activity (PA) guidelines \& spend up to 11 hrs/day sitting.
- Trial name
- NCT03473145
- Testing
- Health Coaching, activPAL inclinometer, Tools to Prompt Standing or Prompt Sit-to-Stand Transitions.
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego