Clinical trials: Aging, completed
Aging
Mindfulness Meditation in Older Adults
The purpose of this study is to test if an 8-week mindfulness meditation training (vs a wait-list control condition) program reduces neurobehavioral reactivity and improves affect regulation in a sample of older adults, as…
- Trial name
- MIND (NCT01532596)
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anemia, Clonal Hematopoiesis
Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly
The prevalence and incidence of anemia tend to increase with advancing age. Relatively low hemoglobin concentrations are a common laboratory finding in the elderly, for the most part judged by physicians as a sign without…
- Trial name
- NCT03907553
- Testing
- targeted genome sequencing
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Depression in Old Age
Programme Evaluation on Effectiveness of The Use of Movement-based x 'Elderspirituality - Fu Le Mun Sum' Intervention to Support Elderly People With Depressive Symptoms
Depression is one of the most common mood disorders in old age, and yet it is frequently under-detected and under-treated. Adopting a train-the-trainer approach, this project intends to utilize the dance movement therapy (DMT)…
- Trial name
- NCT05308082
- Testing
- Dance Movement Therapy (DMT)
- Where
- Hong Kong
- Volunteers
- 135 people
- Sponsor
- The University of Hong Kong
Aging, Undernutrition
Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products
This study aims to assess the digestibility and efficacy of the study groups previously developed innovative plant-based protein and fibre products.
- Conditions
- Aging, Undernutrition, Appetite Loss, Age-Related Sarcopenia
- Trial name
- NCT05420142
- Testing
- Net peripheral AA appearance following ingestion of 3 selected PPF products compared to whey
- Where
- 2 sites in Ireland, Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Wrinkles, Ageing
Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin
Objective of the study is to determine the influence of dietary supplementation with coenzyme Q10 (CoQ10) on skin conditions. 33 healthy female subjects will be randomly assigned to a placebo group, a low-dose (LD) group…
- Conditions
- Wrinkles, Ageing, Photoprotection
- Trial name
- NCT02604641
- Testing
- Quvital LD group, Quvital HD group
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Deglutition Disorders
Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging
Oropharyngeal dysphagia (OD) is the most frequent digestive disorder in older people (>70 years) and has been recently recognized as a geriatric syndrome.
- Trial name
- NCT03050957
- Testing
- menthol
- Volunteers
- 38 people
- Sponsor
- Hospital de Mataró
Aging
Enhancing Function in Later Life: Exercise and Functional Network Connectivity
Physiological and neurocognitive changes experienced as a result of increasing age may influence socioemotional functioning and economic behaviors, yet, the mechanisms through which these changes occur are not well understood.
- Trial name
- FORCE (NCT02068612)
- Testing
- Moderate Intensity Continuous Training+Interval Training, Low Intensity Continuous Training
- Where
- United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Stress, Ageing
The Relaxation vs. Retreat Study
The purpose of this research study is to examine whether a short term meditation intervention can improve health, mood, and biological markers of cellular stress and aging in novice and experienced meditators compared to controls.
- Conditions
- Stress, Ageing, Wellbeing
- Trial name
- R&R (NCT01857830)
- Testing
- Meditation Retreat, Active Comparator Relaxation Group
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vulvo Vaginal Atrophy
Regenerative Treatment of Female Genital Atrophy
Vulvovaginal health is a key aspect of active and healthy aging for all women. Hormonal deprivation that occurs during menopause significantly affects the anatomy and function of urogenital tissues, leading to their atrophy.
- Trial name
- RETREAT-FUGA (NCT07306611)
- Testing
- Mesotherapy with Autologous Platelet-Rich Plasma (PRP) to vulvovaginal area, Mesotherapy with saline solution, Platelet-Poor Plasma Gel
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- AndreiaAntunes
Memory
Resveratrol for Improved Performance in the Elderly
The investigators aim to conduct a randomized placebo controlled pilot study to determine whether resveratrol, a dietary ingredient, supplementation is safe and improves memory and physical performance in older adults.
- Trial name
- RIPE (NCT01126229)
- Testing
- Low dose Resveratrol, High dose Resveratrol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Aging
The Effect of Strength Training and Protein Supplementation in Old Pre-frail Individuals
The aim of this study is to investigate the effects of a lower-body strength training regime combined with protein supplementation in pre-frail elderly individuals.
- Trial name
- NCT03723902
- Testing
- Heavy-load strength training, Protein supplementation
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Muscle Loss
The Effect of Leucine on Carnitine Transport to Skeletal Muscle
The primary aim of the current research project is to explore whether leucine stimulates carnitine transport, and thus affecting muscle carnitine content.
- Trial name
- ROL (NCT05009654)
- Testing
- L-carnitine, L-leucine
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Aging
A Study to Evaluate Efficacy of Dietary Ingredient in Vitality and Metabolic Factors in Healthy Individuals
The present study is a randomized, placebo-controlled, feasibility study to evaluate efficacy of dietary ingredients in vitality \& metabolic factors in healthy individuals.
- Trial name
- NCT06188949
- Testing
- Dolichos biflorus (Horsegram) seed extract, Carica papaya leaves extract
- Where
- 2 sites in India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Aging Well
Telematic Dance Intervention on Quality of Life of Older
The aim of this study is to analyse the effectiveness of a telematic dance intervention on the quality of life of older people. This project is a controlled, randomized clinical trial.
- Trial name
- NCT04681976
- Testing
- Telematic dance program
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging
Inadequate Protein Intake at Specific Meals and Functionality in Middle to Older Aged Mexican Adults
This study sought to determine if the inadequate protein intake per meal (defined as eating <30 g protein or 0.4 g protein/kg body mass) at specific meals (breakfast, lunch, dinner) is associated with functionality in middle to…
- Trial name
- NCT03846440
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Health Status Disparities, Subjective Health
Self-management, Health Literacy and Social Capital in Socioeconomically Disadvantaged Older Adults
Motivations: Socio-economic and education determinants have a big impact on health outcomes, in terms of worse health status in populations living in more disadvantaged conditions.
- Conditions
- Health Status Disparities, Subjective Health, Self Care, Social Capital
- Trial name
- AEQUALIS (NCT02733523)
- Testing
- Program "Sentirnos bien" (Feeling well)
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Fundacio Salut i Envelliment UAB
Aging
Effects of Two Types of Concurrent Training in Functional Performance and Cognitive Function of Older Adults
The goal of this randomized controlled clinical trial is to identify and compare the impacts of traditional concurrent training and concurrent training consisting of strength training combined with dance classes on functional…
- Trial name
- NCT05859243
- Testing
- Traditional concurrent training, Concurrent training consisting of strength training combined with dance classes
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eduardo Lusa Cadore
Cognitive Impairment, Predictive Model
Risk Prediction and Its Intelligent Assessment for Cognitive Impairment Among Community-dwelling Older Adults
Cognitive impairment is one of the core early signs of dementia, and it is also a key stage for community-based dementia prevention.
- Conditions
- Cognitive Impairment, Predictive Model, Aging, Cohort
- Trial name
- NCT05385874
- Where
- China
- Volunteers
- 13,228 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Inhibition (Psychology), Updating
Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates
Formal education and cognitively stimulating hobbies and profession have a protective effect against age-related cognitive decline and Alzheimer's disease.
- Conditions
- Inhibition (Psychology), Updating, General Knowledge, No Training
- Trial name
- NCT03532113
- Testing
- Updating, Inhibition, General knowledge
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal