Clinical trials: Aging Problems
Stroke, Problem of Aging
Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement
The purpose of this study is to find out if quercetin can increase blood levels of hypoxia-inducible transcription factor 1 (HIF-1 protein) and to see if there is a corresponding increase in blood flow to the brain.
- Trial name
- Quercetin (NCT01376011)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Aging Well, Aging Problems
Aquatic Exercise for Cognition and Mobility in Older Adults
The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.
- Conditions
- Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady
- Trial name
- NCT05501249
- Testing
- Aquatic Integrated Cognitive Motor Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emily Dunlap
Pain, Aging Problems
Efficiency of Facial Expression Diagnostic System in Pain Assessment After Geriatric Surgery
By integrating the methods used in the assessment of pain in geriatric surgery patients with literature, theory and research, this study aims to: evaluate the effectiveness of the facial diagnosis system in the evaluation of pain…
- Trial name
- NCT05756140
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Aging, Aging Problems
Development and Evaluation of a Psychological Intervention in Videogame Format for the Promotion of Active Aging
The social and health challenges of the aging population have led to the recommendation of active aging programs to increase the number of healthy and independent elderly people.
- Trial name
- GAMEPROAGING (NCT04982497)
- Testing
- Video game based intervention, Control group
- Where
- Spain
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Insulin Resistance, Age Problems
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.
This study intends to examine the effect of a commercially available nutritional supplement, Beta-hydroxy-beta-methylbutyrate(HMB) on whole-body responses to a sugar load.
- Trial name
- NCT03018496
- Testing
- Beta-Hydroxy-Beta-Methylbutyrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Memory Problems
Brain Fitness APP for Aging With a Healthy Brain
Memory and cognitive declines are associated with normal brain aging but are also precursors to dementia, in particular the so called the pandemic of the century, Alzheimer's disease.
- Trial name
- NCT03600545
- Testing
- Brain Fitness App
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Older Adults, Age Problem
Influence and Relationships Between Square-stepping Exercise and Brain Activation, Cognitive Function, Physical Performance in Healthy Older Adults
Background and purposes: Square-stepping exercise (SSE) has been proved to be an effective intervention for motor and cognitive function in older adults. However, the underlying mechanism of SSE still remains undetermined.
- Trial name
- NCT05891574
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Aging Problems, Balance; Distorted
Comparison of the Effects of Different Living Environments in Geriatric Individuals: A Pilot Study
In Turkey, 63% of geriatric people who make up approximately 8.3% of the entire population live in their own living environment, 36% live with their children and 1% live in nursing homes.
- Conditions
- Aging Problems, Balance; Distorted, Pain, Quality of Life
- Trial name
- NCT04873791
- Testing
- Assessment of geriatric individuals living in home environment and nursing home.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sarcopenia, Frailty
Implementation of ProMuscle in Daily Practice
Implementation of a previously shown (cost-)effective combined lifestyle intervention for community living older adults, ProMuscle, in at least four of the eight communities of the 'Foodvalley' in the Netherlands.
- Conditions
- Sarcopenia, Frailty, Aging Problems
- Trial name
- PUMP-fit (NCT05672004)
- Testing
- PUMP-fit strategy (implementation toolbox), Implementation as usual
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Aging Problems, Wrinkle
Comparing Polydioxanone Thread Embedding Acupuncture and Manual Acupuncture for Nasolabial Fold Reduction
This study was aimed to compare the effectiveness of polydioxanone thread embedding acupuncture and manual acupuncture on the reduction of the nasolabial fold.
- Trial name
- NCT05098912
- Testing
- Manual acupuncture, Thread embedding acupuncture
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cognitive Impairment, Dementia
Hainan Community Cognition Cohort
This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up.
- Conditions
- Cognitive Impairment, Dementia, Age Problems
- Trial name
- NCT06686186
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hainan Medical College
Aging Problems
Effect of Floorball on Healthy Subjects
To investigate the effect of floorball on health and performance in healthy subjects over 65 years.
- Trial name
- NCT03371238
- Testing
- Floorball
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Aging, Age Problem
Impact of Comprehensive Dietary Counseling on Dietary Quality, Mental Health, and Quality of Life in Older Adults
As a person ages, an incidence of mental distress such as depression and anxiety increases while the quality of life decreases. Singapore's population is aging rapidly and older adults may suffer from mental distress and…
- Conditions
- Aging, Age Problem, Age-related Cognitive Decline, Age-Related Atrophy
- Trial name
- NCT03702335
- Testing
- Dietary Counselling
- Where
- 2 sites in Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Age Problem, Healthy Aging
Resistance Training on Elderly Resilience
Background: There is on one hand sufficient evidence showing strong association between resilience and self-rated successful aging.
- Conditions
- Age Problem, Healthy Aging, Activity, Motor
- Trial name
- NCT04690465
- Testing
- Resistance training, Eight-form Yang-style Tai Chi program
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Aging Problems
Dose-response of Anteroposterior Mobilizations in Weight Bearing Talus Dorsiflexion
Ankle mobility limitations are common in older adults. A possible treatment to restore joint mobility is manual therapy based on mobilization techniques, in this case, applied on the ankle joint.
- Trial name
- ANKLE_WBROM (NCT04563663)
- Testing
- Posteriorization of the talus.
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Age Problems, Cognitive Impairment
Feasibility Aquatic Physical Exercise to Reduce Falls in Institutionalized Elderly
This is a pilot randomized control trial with single blinding of the assessor that will be conducted in two nursing homes residence to evaluate the applicability of a physical exercise program performed in an aquatic environment…
- Conditions
- Age Problems, Cognitive Impairment, Elderly, Postural Balance
- Trial name
- PrePhysFalls (NCT03019211)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Aging Problems
Effects of Feet and Ankle Mobilization on Balance of Older Adults
This study aims to assess whether mobilization of the ankle and foot produces significant improvements in the balance of the elderly.
- Trial name
- FEET_BALANCE (NCT03092869)
- Testing
- Feet and Ankle Mobilization, Proprioceptive Training
- Where
- 2 sites in Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Dyslexia, Aging Problems
Neuroplasticity of Multisensory Cortical Areas Induced by Musical Training: a Translational Approach (MusicPlast)
Exploiting recent methodological advancements, several neuroimaging studies suggested that multisensory integration emerges from a dynamic interplay of distributed regions operating in large-scale networks.
- Trial name
- MusicPlast (NCT03786185)
- Testing
- MusicPlast, MusicPlast Control
- Where
- Greece
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Problem of Aging
A Slit Face Trial Using Micro-injections of Transparent Hyaluronic Acid Gel for Rejuvenation of the Cheek
Soft tissue augmentation with injectable hyaluronic acid (HA) is a well-established modality for the correction of facial volume loss, fat atrophy, fine lines, and wrinkles.
- Trial name
- NCT02679924
- Testing
- Hyaluronic Acid filler
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Isabella Guiha