Clinical trials: Aging and Cognitive Health
Aging, Physical Activity
NEUROmuscular Training for Enhanced AGE Longevity
In recent years the research group on Prevention and Health in Exercise and Sport (PHES) has carried out numerous studies that have provided current and convincing evidence of the benefits of physical activity and exercise for…
- Conditions
- Aging, Physical Activity, Training
- Trial name
- NEUROAGE (NCT06620666)
- Testing
- Water-based power resistance training + Dietary supplement I (WPowDSI), Elastic band-based power resistance training + Dietary supplement I (EBPowDSI), Elastic band-based eccentric resistance training + Dietary supplement II (EBEccDSII)
- Where
- Spain
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Resilience, Cognitive Function and Well-Being
Aging Resilience Through Microbiota Optimization and Regulation
Sarcopenia, characterized by the progressive loss of muscle mass and strength in older adults, is a key factor in health deterioration.
- Conditions
- Resilience, Cognitive Function and Well-Being, Muscle Function, Handgrip Strength Test, Insulin Sensitivity
- Trial name
- ARMOR (NCT06649981)
- Testing
- FMT capsule
- Where
- 2 sites in Chile
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gonzalo Jorquera, PhD
Mild Cognitive Impairment (MCI), Ageing
Exploring and Evaluating the Impact of 'Refresh and Reconnect!'
Dementia and mild cognitive impairment are a rising concern for the ageing population in Singapore, leading to diminished quality of life and health outcomes.
- Conditions
- Mild Cognitive Impairment (MCI), Ageing, Mild Dementia, Well-being
- Trial name
- ReCognition (NCT06805578)
- Testing
- Heritage art programme
- Where
- Singapore
- Volunteers
- 108 people
- Sponsor
- Duke-NUS Graduate Medical School
Aging, Cognitive Decline
ACHIEVE Brain Health Follow-Up Study
The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs.
- Conditions
- Aging, Cognitive Decline, Mild Cognitive Impairment, Dementia
- Trial name
- ACHIEVE-BHFU (NCT05532657)
- Testing
- Hearing intervention, Successful aging/delayed hearing intervention
- Where
- 4 sites in United States
- Volunteers
- 629 people
- Sponsor
- Johns Hopkins University
Healthy Aging
Virtual Reality Study - COVID-19 Protocol
The overarching goal of this pilot clinical trial is to use a novel virtual reality (VR)-based intervention that simultaneously engages physical and cognitive activity aimed at improving brain and cognitive outcomes in older…
- Trial name
- NRVR (NCT04678778)
- Testing
- Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Aging, Cognitive Decline
Social and Cognitive Online Training: the SCOT Project
Social isolation and reduced involvement in cognitive activities are associated with repercussions on cognitive well-being and health status in elderly adults.
- Trial name
- SCOT (NCT05023187)
- Testing
- SCOT, CON
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Trento
Traumatic Brain Injury, Aging
The Long-term Consequences After Traumatic Brain Injury in the Elderly
A better understanding of the injury patterns, injury severity, risk profiles, consequences and impact of Traumatic Brain Injury (TBI) in the elderly population is necessary due to the increasing incidence and prevalence of TBI…
- Conditions
- Traumatic Brain Injury, Aging, Cognitive Impairment, Quality of Life
- Trial name
- NCT04074850
- Where
- Belgium
- Volunteers
- 47 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sedentary Lifestyle
Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health
Although exercise is known to delay cognitive decline and decrease our risk of Alzheimer's Disease, there is a lack of understanding of how exercise protects the aging brain.
- Trial name
- BIKE (NCT02453178)
- Testing
- Cycling
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cancer, Mental Health
Healthspan Connect Programme of Research
Healthspan Connect is a new research programme designed to understand what helps people stay healthy as they age. The programme will explore how lifestyle, environment, genetics, and social factors influence healthy ageing and…
- Conditions
- Cancer, Mental Health, Ageing Well, Resilience
- Trial name
- NCT07209774
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy Aging
Effect of Mindfulness on EEG Brain Activity for Cognitive and Psychological Well-being in the Elderly
As the worldwide population of older adults rapidly increases over the coming years, effective strategies are needed to help this population to maintain and enhance physical, cognitive, and psychological well-being.
- Trial name
- NCT05941143
- Testing
- mindfulness-based intervention
- Where
- Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Aging, Alzheimer Disease
Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention
Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's…
- Conditions
- Aging, Alzheimer Disease, Life Style, Healthy, Exercise
- Trial name
- LIBRA-NET (NCT06986096)
- Testing
- Aerobic-strength training and nutritional counseling, Cognitive training and stretching.
- Where
- Slovakia
- Volunteers
- 40 people
- Sponsor
- Slovak Academy of Sciences
Mild Cognitive Impairment, Normal Aging
An Observational Study Using Multimodal Sensors to Measure Cognitive Health in Adults and Distinguish Mild Cognitive Impairment From Normal Aging
The primary objectives are to develop and validate a classifier using multimodal passive sensor data and metrics derived from normal iPhone and Apple Watch usage to distinguish individuals with normal cognition from those with…
- Trial name
- Intuition (NCT05058950)
- Where
- United States
- Volunteers
- 22,720 people, healthy volunteers welcome
- Sponsor
- Biogen
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley