Clinical trials: Agitated Behaviour
Agitation,Psychomotor, Disruptive Behavior
A Medical Cannabis Oil for Treatment of Agitation and Disruptive Behaviors in Subjects With Dementia.
This double-blind, placebo-controlled study is designed to assess the effectiveness of, MediCane's medical cannabis oil extracted from MediCane's proprietary strain into GMP-grade olive oil, as an add-on therapy to standard of…
- Conditions
- Agitation,Psychomotor, Disruptive Behavior, Dementia, Alzheimer Disease
- Trial name
- NCT06217146
- Testing
- Medical Cannabis
- Where
- 3 sites in Israel
- Volunteers
- 24 people
- Sponsor
- M. H MediCane Ltd.
Akathisia
Akathisia (Restless Legs Syndrome) in People With Schizophrenia and Mental Retardation
Akathisia is a movement disorder that is often a side effect of certain psychiatric drugs. People with akathisia are unable to sit or keep still, complain of restlessness, fidget, rock from foot to foot, and pace.
- Trial name
- NCT00065286
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Schizophrenia
Examining Rapid Acting Intra-Muscular Olanzapine in Japanese Patients With Schizophrenia
The purpose of this study is to examine the clinical therapeutic dose in Japanese agitated patients with schizophrenia.
- Trial name
- NCT00485810
- Testing
- Olanzapine Hydrochloride
- Where
- Japan
- Volunteers
- 31 people
- Sponsor
- Eli Lilly and Company
Respiratory Insufficiency, Psychomotor Agitation
Loxapine and Weaning From Ventilator
Patients may be very agitated during the weaning period from mechanical ventilation. Administration of loxapine, a neuroleptic that does not notably affect ventilatory drive, may help in obtaining an adequate level of cooperation…
- Trial name
- NCT00122733
- Testing
- loxapine
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Risk Behavior, Agitation
Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.
There is a risk of falls and injuries in bedridden hospitalized patients, increased in agitated or confused patients. In neurosurgery departments, brain damaged patients can present a loss of consciousness of risky behaviors and…
- Conditions
- Risk Behavior, Agitation, Hospitalization, Bedridden Patients
- Trial name
- DECORIPAA (NCT05522647)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Brain Injuries, Craniocerebral Trauma
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI).
- Conditions
- Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
- Trial name
- NCT01322048
- Testing
- IV Propranolol and Per Tube Clonidine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Depression With Prominent Agitation
The Quietude Study: Quetiapine Use for Agitated Depression
Most individuals with major depressive disorder manifest clinically significant agitation. Concurrent agitation in a depressed individual is associated with an intensification of mood symptoms, decreased probability of recovery…
- Trial name
- NCT01363310
- Testing
- Quetiapine XR, Escitalopram
- Where
- 11 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Physicians Research And Education Network
Emergence Agitation
Small Doses of Dexmedetomidine for Emergence Agitation
Dexmedetomidine Hydrochloride is a kind of high selectivity alpha 2 agonists adrenaline, can inhibit the activity of sympathetic nerve, and reduce the adverse effects of stress reaction in anesthesia recovery period.Literatures…
- Trial name
- NCT02169843
- Testing
- Sevoflurane, Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tang-Du Hospital
Alzheimer's Disease
CATIE-Alzheimer's Disease Trial
The CATIE Alzheimer's Disease Trial is part of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Project. The study is for people with Alzheimer's disease who are having trouble with their thinking or…
- Trial name
- NCT00015548
- Testing
- Olanzapine, Quetiapine, Risperidone
- Where
- 34 sites in United States
- Volunteers
- 450 people
- Sponsor
- National Institute of Mental Health (NIMH)
Schizophrenia, Schizoaffective Disorder
Intramuscular (IM) Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia
The aim of this study was to compare the efficacy and safety of intramuscular 10 mg olanzapine versus intramuscular 5 mg haloperidol plus lorazepam 2 mg in the treatment of acute agitated schizophrenic patients of Taiwanese…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Agitation
- Trial name
- NCT00797277
- Testing
- IM olanzapine, IM haloperidol plus lorazepam
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- National Taiwan University Hospital
Alzheimer's Disease
Memantine for Agitation and Aggression in Severe Alzheimer's Disease
Alzheimer's disease (AD) is the most common form of dementia and is characterized by both cognitive and behavioural symptoms ("Behavioural and Psychological Symptoms of Dementia"; BPSD).
- Trial name
- NCT00401167
- Testing
- memantine
- Where
- 2 sites in Canada
- Volunteers
- 31 people
- Sponsor
- Sunnybrook Health Sciences Centre
Supraventricular Tachycardia
Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound
Supraventricular tachycardia (SVT) is an abnormally fast heart rhythm arising from improper electrical activity in the upper part of the heart.
- Trial name
- NCT04051541
- Testing
- Agitated saline push
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
ADHD, Iron-deficiency
Impact of Iron Supplementation Treatment on Brain Iron Concentrations
The goal of the present study is to provide novel data to evaluate brain iron concentration as a mediator of the association between iron supplementation treatment and improvement in symptoms of ADHD and RLS in children…
- Conditions
- ADHD, Iron-deficiency, Restless Legs Syndrome, Periodic Limb Movement Sleep Disorder
- Trial name
- NCT04144790
- Testing
- ferrous sulfate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
ADHD, Sleep Problems
A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep
The goal of this clinical trial is to learn if iron supplementation works to restless sleep in youth with ADHD. A second goal is to learn if iron supplementation helps to ease ADHD symptoms.
- Trial name
- NCT07061470
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Agitation
Ketamine Versus Midazolam for Prehospital Agitation
This research study is being done to figure out the best approach to treatment of pre-hospital agitation. It will compare two tiered dosing treatment protocols, one ketamine-based and one midazolam-based.
- Trial name
- NCT03554915
- Testing
- Ketamine-based protocol, Midazolam-based protocol
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Hennepin Healthcare Research Institute
Psychomotor Agitation, Behavioral Disorder
Clinical Trial of Peer Support in the ED (PCORI)
The purpose of this study is to conduct a clinical trial that tests the acceptability, fidelity, and feasibility of a peer support modified intervention for agitation management within the emergency department.
- Trial name
- NCT06556069
- Testing
- Peer-Support Enhanced Agitation Code Team (PACT)
- Where
- United States
- Volunteers
- 57,870 people, healthy volunteers welcome
- Sponsor
- Yale University
Psychomotor Agitation, Schizophrenia
A Study of Staccato Loxapine (ADASUVE®) for Inhalation
Phase 3 safety and efficacy study of Staccato Loxapine in the treatment of acute agitation in schizophrenic or bipolar disorder patients.
- Conditions
- Psychomotor Agitation, Schizophrenia, Bipolar Disorder
- Trial name
- NCT04148963
- Testing
- Inhaled loxapine
- Volunteers
- 150 people
- Sponsor
- Lee's Pharmaceutical Limited
Agitation, Emergence
Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries
emergence agitation is seen in around 68% after nasal surgeries. Agitated patients needs more staff and nurses to control their abnormal movement which leads to self extubation , removal of catheters and bruises in the…
- Trial name
- NCT04018157
- Testing
- "Ketamine" and "dexmedetomidine" and "propofol" and "0.9%saline"
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Polysomnography, Sleep Apnea Syndromes
Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep Database
The primary purpose of the proposed study is to validate our previously developed predictive model for adults with obstructive sleep apnea using (i) clinical data from multiple large academic centers, (ii) a longer follow-up…
- Conditions
- Polysomnography, Sleep Apnea Syndromes, Risk Factors, Prognosis
- Trial name
- NCT03834792
- Testing
- No intervention but exposure
- Where
- Canada
- Volunteers
- 5,155 people
- Sponsor
- Ottawa Hospital Research Institute
Respiratory Failure, Delirium
Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM)
Non-Invasive Mechanical Ventilation (NIV) has been increasingly used in the treatment of acute respiratory failure. Notwithstanding failure rates still remains high, ranging from 5% to 60%.
- Conditions
- Respiratory Failure, Delirium, Agitation,Psychomotor, Pain
- Trial name
- NIVILIUM (NCT03880084)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- University of Modena and Reggio Emilia