Clinical trials: Agitated Behaviour
Dementia, Agitation
Virtual Reality to Advance Dementia Care and Quality of Life
The goal of this feasibility clinical trial is to learn whether supervised virtual reality (VR) sessions can be safely and practically provided to adults aged 55 years and older with moderate-to-severe dementia who experience…
- Conditions
- Dementia, Agitation, Behavioural and Psychological Symptoms of Dementia, Major Neurocognitive Disorder
- Trial name
- VR-Care (NCT07893678)
- Testing
- Supervised Virtual Reality Sessions
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Behavior, Agitation
Long Term Memory Preoperative Preparation Reduce Post Operative Behavioral Change
The study is designed to test the hypothesis that long term memory created by preoperative video information can reduce the incidence of post operative behavioral changes.
- Trial name
- NCT04039269
- Testing
- Preoperative video information
- Where
- Thailand
- Volunteers
- 192 people
- Sponsor
- Prince of Songkla University
Emergence Agitation, Emergence Delirium, Anesthesia
Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric Patients Undergoing Microscopic Middle Ear Surgery.
This study is designed to evaluate the effectiveness of ultrasound-guided greater auricular nerve block (GAN) on the reduction of emergence agitation (EA) occurrence and EA severity in children who are receiving general…
- Conditions
- Emergence Agitation, Emergence Delirium, Anesthesia, Emergence From Anesthesia, Emergence Delirium
- Trial name
- NCT07435675
- Testing
- ultrasound-guided greater auricular nerve block (GANB)
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Alzheimer Disease, Dementia
Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing the severity of agitation among participants and 2) determine whether…
- Conditions
- Alzheimer Disease, Dementia, Major Neurocognitive Disorder With Aggressive Behavior
- Trial name
- NCT04436081
- Testing
- THC-free CBD Oil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eastern Virginia Medical School
Surgery, Stress
The Effects of Healing Touch on Post Operative Pediatric Patients
The goal of this study is to assess the benefits of Healing Touch, an energy based therapy on post-operative discomfort and the rate of recovery in children.
- Conditions
- Surgery, Stress, Pain, Children
- Trial name
- NCT01738308
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep Disorders, Circadian Rhythm, Insomnia
Actigraphic Analysis of Treatment Response
The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.
- Conditions
- Sleep Disorders, Circadian Rhythm, Insomnia, Psychomotor Agitation
- Trial name
- NCT00723580
- Testing
- risperidone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Child Psychopharmacology Institute
Agitation,Psychomotor, Dementia
Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia
This is an adaptive Phase 1b/2 trial design. It is randomized, double-blind, placebo-controlled, multiple ascending dose study assessing efficacy, pharmacokinetics, safety and tolerability of BXCL-501 dosing in adult (65 years…
- Trial name
- TRANQUILITY (NCT04251910)
- Testing
- Sublingual film containing Dexmedetomidine
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- BioXcel Therapeutics Inc
Agitation
Midazolam Effect on Agitation Postnasal Surgery
Postoperative agitation is a common complication, it's incidence post head and neck surgery is around 11-26%. Avoiding such complication is mandatory to facilitate patient's recovery and reduce risk of postoperative agitation…
- Trial name
- NCT05165914
- Testing
- Intravenous midazolam before emergence from general anesthesia, Intravenous normal saline before emergence from general anesthesia
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jordanian Royal Medical Services
Agitation, Dementia
Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)
A study to determine the safety and efficacy of BXCL501 dosing for episodes of agitation associated with dementia when they occur (given as needed [PRN]), for a maximum of 168 doses within a 12-week treatment period.
- Trial name
- NCT05665088
- Testing
- BXCL501
- Where
- 7 sites in United States
- Volunteers
- 13 people
- Sponsor
- BioXcel Therapeutics Inc
Agitation
Acute Agitation in Emergency Psychiatry
The purpose of the study is to improve the pharmacological treatment of psychiatric patients with acute agitation.
- Trial name
- NCT06752616
- Testing
- Sublingual Dexmedetomidine, Buccal midazolam, Oral lorazepam
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Lone Baandrup
Dementia
Effects of Snoezelen Multisensory Therapy on Older Adults With Dementia
This randomized, controlled, longitudinal clinical trial investigates the effects of Snoezelen Multisensory Therapy (SMT) as an adjunct to standard therapy (ST) in older adults with dementia.
- Trial name
- SMT (NCT07657208)
- Testing
- Snoezelen Multisensory Therapy, Standard Therapy
- Where
- Slovenia
- Volunteers
- 63 people
- Sponsor
- University of Primorska
Alzheimer's Disease, Psychosis
Treatment of Psychosis and Agitation in Alzheimer's Disease
Clinically, many patients with AD show no response or minimal response to antipsychotics for symptoms of agitation/aggression or psychosis, or they have intolerable side effects on these medications.
- Conditions
- Alzheimer's Disease, Psychosis, Agitation
- Trial name
- NCT02129348
- Testing
- Lithium
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- New York State Psychiatric Institute
Transesophageal Echocardiography Contrast Agents
Agitated Saline, Albumin, or Propofol-albumin Mixture for Enhanced Contrast in TEE Examinations
This is a prospective, randomized, controlled study to determine if albumin and propofol or albumin only will provide superior qualitative contrast enhancement during TEE bubble studies compared to agitated saline.
- Trial name
- NCT02613052
- Testing
- normal saline, human albumin, human albumin and propofol
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Diego
Is an Only Child
Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.
The purpose of this study is to determine efficacy of intraoperative clonidine to prevent postoperative agitation in pediatric anesthesia with sevoflurane.
- Trial name
- NCT02181543
- Testing
- Clonidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Hypothermia; Anesthesia, Agitation, Emergence
Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation
The main aim of our study was to investigate the relationship between perioperative hypothermia and postoperative emergence agitation.
- Conditions
- Hypothermia; Anesthesia, Agitation, Emergence, Postoperative Complications, Hypothermia Following Anesthesia
- Trial name
- NCT06543134
- Testing
- surgery, sedation scale
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Critical Illness
Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit
The objective of this study is to administer music therapy to patients in the pediatric intensive care unit (PICU) in order to observe how music affects patient agitation, vital signs, and overall recovery in the unit.
- Trial name
- NCT03453814
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- State University of New York at Buffalo
Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant
Nabilone for Agitation in Frontotemporal Dementia
The primary goal of this study is to test the hypothesis that oral nabilone treatment will reduce agitation compared with placebo in patients with Frontotemporal Dementia (both behavioural variant frontotemporal dementia and…
- Conditions
- Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant, Primary Progressive Aphasia, bvFTD
- Trial name
- Nabilone-FTD (NCT05742698)
- Testing
- Nabilone
- Where
- 7 sites in Canada
- Volunteers
- 3 people
- Sponsor
- Simon Ducharme, MD
Emergence Delirium
AGItated Patients Management: intraNASAL Midazolam vs Intramuscular Loxapine
This study is a non-inferiority phase III randomized trial evaluating the effect of intranasal midazolam versus intramuscular loxapine on the rapid tranquilization of agitated patient in emergency department.
- Trial name
- AGINASAL (NCT05324852)
- Testing
- Intranasal midazolam, Intramuscular loxapine
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Agitation
The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia
The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
- Trial name
- NCT01440114
- Testing
- fentanyl, NSS
- Where
- Thailand
- Volunteers
- 144 people
- Sponsor
- Prince of Songkla University
Sleep Disorder, Sleep Disorder Parasomnia
Mainz Register of Patients With Sleep Disorders
Prospective longitudinal observational registry study of all patients with sleep disorders treated in the Mainz Comprehensive Epilepsy and Sleep Medicine Center with the focus on the course of the disease and quality of life.
- Conditions
- Sleep Disorder, Sleep Disorder Parasomnia, Narcolepsy, Sleep Apnea
- Trial name
- MAINZ-SLEEPREG (NCT05321355)
- Testing
- Implantation of vagus nerve stimulation according to clinical indication
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Johannes Gutenberg University Mainz