Clinical trials: Aids
Acquired Immunodeficiency Syndrome, Healthy Volunteers
Effects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious Diarrhea
This study is intended to evaluate: 1. Any changes in the gut microbiome from baseline compared to end of study in both healthy (HIV-negative) subjects and HIV+ patients with or without chronic diarrhea, following one month of…
- Conditions
- Acquired Immunodeficiency Syndrome, Healthy Volunteers, HIV/AIDS, HIV Diarrhea
- Trial name
- NCT04192487
- Testing
- Crofelemer delayed-release tablets 125mg
- Where
- 3 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Napo Pharmaceuticals, Inc.
HIV Infections
Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe
The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in…
- Trial name
- NCT00390949
- Testing
- Peer education among commercial sex workers and clients, Condom distribution and promotion, Syndromic treatment of sexually transmitted infections
- Where
- Zimbabwe
- Volunteers
- 9,454 people, healthy volunteers welcome
- Sponsor
- Imperial College London
HIV Prevention
Demonstration Project on the Feasibility to Implement PrEP in MSM and TG Women
The purpose of the study is to evaluating the acceptability, use and adherence of a pre-exposure prophylaxis (PrEP) program using the co-formulation tenofovir disoproxil fumarate 300 mg/emtricitabine 200 mg (TDF/FTC) administered…
- Trial name
- NCT03043326
- Testing
- Tenofovir Disoproxil Fumarate and Emtricitabine
- Where
- 5 sites in Peru
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Asociación Civil Impacta Salud y Educación, Peru
HIV Infections
Effects of Storage on Lactate in Blood Samples
The purpose of this study is to determine whether laboratory storage of samples affects the amount of lactate over 3 years. Lactate is a natural substance normally present in the body.
- Trial name
- NCT00011050
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pregnancy, Human Immunodeficiency Virus
'HI-4-TU' Study: Health Improvement for Teen Ugandans Study
This randomized clinical trial is an adolescent focused implementation science study directed at improved social support and prevention of both HIV/STI's and subsequent unplanned pregnancies.
- Conditions
- Pregnancy, Human Immunodeficiency Virus, Sexually Transmitted Diseases
- Trial name
- NCT02845284
- Testing
- enhanced group support, enhanced individual support
- Where
- Uganda
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV/AIDS, Sexually Transmitted Infections
A Pragmatic Trial to Expand Youth-friendly HIV Self-testing
The current study extends the study team's earlier efforts described in ClinicalTrail ID#: NCT04070287 and NCT03874663. The I-TEST (Innovative Tools to Expand Youth-friendly HIV Self-Testing) study known locally as the 4 Youth by…
- Trial name
- I-TEST (NCT04710784)
- Testing
- Sexual health information, I-TEST branded HIVST package, Follow-up testing and clinic assessments
- Where
- Nigeria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Tuberculosis
Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults
The study is a randomized, double-blind, placebo-controlled, multicenter, clinical trial to assess the prophylactic efficacy, safety, and immunogenicity of the investigational M72/AS01E-4 Mtb vaccine when administered…
- Trial name
- NCT06062238
- Testing
- M72/AS01E-4 Mycobacterium tuberculosis investigational vaccine
- Where
- 54 sites in Indonesia, Kenya and 3 more
- Volunteers
- 20,080 people, healthy volunteers welcome
- Sponsor
- Gates Medical Research Institute
HIV/AIDS, HIV Prevention
Evaluating Distribution of a Tenofovir Douche With Tap Water Douching and Simulated Receptive Anal Intercourse
DREAM-02 is a phase 1, open label study to evaluate different sequences of tap water douching and simulated receptive anal intercourse (sRAI) in the presence of a tenofovir douche designed to confer protection from Human…
- Trial name
- DREAM-02 (NCT04195776)
- Testing
- Tenofovir Douche
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Supplementation, Sports
Acute Sodium Bicarbonate Supplementation in Female Basketball Players
This randomized, double-blind, placebo-controlled crossover study aims to evaluate the effect of acute sodium bicarbonate supplementation, compared with placebo, on physical capacity and blood biochemical marker concentrations in…
- Trial name
- NCT07730606
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Krzysztof Durkalec-Michalski
HIV Infections
Evaluating the Safety and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults Who Have Participated in Previous HIV Vaccine Clinical Trials and in Adults Who Have Not Participated in Previous HIV Vaccine Clinical Trials
The purpose of this study is to evaluate the safety and immune response to an HIV vaccine in healthy, HIV-uninfected adults who have participated in a previous HIV vaccine clinical trial and in healthy, HIV-uninfected adults who…
- Trial name
- NCT01376726
- Testing
- Sub C gp140 Vaccine, MF59C.1 Adjuvant
- Where
- 3 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Sexually Transmitted Diseases
Parents Matter!: Interventions to Promote Effective Parent-Child Communication
Parents Matter is a community-based project whose goal it is to develop and test an intervention designed to promote effective parent-child communication about sexuality in order to promote sexual health among adolescents.
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Pregnancy
- Trial name
- NCT00137943
- Testing
- Full Parent communication intervention, Brief Parent Communication Intervention, Control Parent Intervention
- Where
- 3 sites in United States
- Volunteers
- 2,210 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Hearing Loss, Adult-Onset, Hearing Aids
Use of Airpod Pros as Assistive Technology
The goal of this study is to investigate the suitability and effectiveness of the AirPod Pro 2nd and 3rd generation (AP) as hearing assistive technology for individuals with mild-to-moderate hearing loss when listening in noisy…
- Trial name
- NCT06840015
- Testing
- Airpod Pro as hearing assistive technology
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
HIV, Alcohol Use
Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings
Alcohol use is increasingly recognized as a key factor in morbidity and mortality among HIV-positive individuals and represents an important public health concern, given its associations with medication non-adherence, increases…
- Conditions
- HIV, Alcohol Use, Medication Adherence
- Trial name
- PLUS (NCT02390908)
- Testing
- Immediate PLUS intervention, Wait-list PLUS intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Healthy
The Effects of the Direct Acting Antiviral Agent Boceprevir on the Pharmacokinetics of Maraviroc in Healthy Volunteers
Infection by both HIV and hepatitis C virus (HCV)is frequent due to similar transmission modes. Near 20% of people living with HIV are also infected by HCV.
- Trial name
- NCT01627717
- Testing
- Maraviroc (5 days), Maraviroc and boceprevir (14 days)
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
HIV Infection
Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use
The overall objective is to determine the influence of timing of ART initiation and alcohol consumption on HIV disease course. ART initiation immediately after HIV infection largely results in smaller HIV reservoir and lower…
- Trial name
- MERLIN (NCT02744040)
- Testing
- ART initiation at time of HIV diagnosis, ART at 24 weeks
- Where
- Peru
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
HIV Infections
Safety and Acceptability of PRO 2000 Vaginal Gel in HIV Uninfected Women in India
PRO 2000 Gel is designed to be inserted into the vagina to protect women from getting HIV during sex. So far, PRO 2000 Gel has been tested for safety in 136 women from Europe and the United States.
- Trial name
- NCT00081640
- Testing
- PRO 2000/5 Gel (P)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Endothelial Dysfunction
Use of EndoPAT for Measurements of Endothelial Dysfunction in HIV Infected Children and Healthy Controls
Our objective is to determine whether HIV infected youth have higher level of endothelial dysfunction, as measured by Peripheral Arterial Tonometry, when compared to age matched healthy controls.
- Trial name
- NCT02324179
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Infections
A Test of Behavioral Intervention for Women at High Risk for HIV Infection
The purpose of this study is to find out if it is possible to conduct a group counseling program for women at risk for HIV infection. Women have been the fastest-growing group with new AIDS diagnoses.
- Trial name
- NCT00006440
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Medication Adherence, HIV Prevention
PrEP Affect Regulation Treatment Innovation
This multi-site randomized controlled trial enrolling sexual minority men who use stimulants and are currently taking pre-exposure prophylaxis (PrEP).
- Conditions
- Medication Adherence, HIV Prevention, Stimulant Use
- Trial name
- PARTI (NCT04899024)
- Testing
- PARTI, Attention-Control, Contingency Management for PrEP Adherence
- Where
- 2 sites in United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Florida International University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.