Clinical trials: Air Pollution
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Asthma
Asthma & Exposure to Peaks in Particulate Air Pollution
We are testing the following two hypotheses: 1) Peaks in hourly exposures to airborne particulate matter (PM) of outdoor origin will be more closely associated with acute asthmatic responses to particles than 24-hour average…
- Trial name
- NCT00013728
- Volunteers
- 24 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Chronic Obstructive Pulmonary Disease (COPD), Exacerbation of COPD
Laying the Foundation for Building a Resilient KPNC Community in the Face of Worsening Air Quality Due to Wildfire Smoke
The overarching goal of this project is to conduct a pilot intervention in high-risk Kaiser Permanente Northern California patients with chronic obstructive pulmonary disease to mitigate their exposure to poor air quality and…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Exacerbation of COPD, Exacerbation of Chronic Obstructive Pulmonary Disease
- Trial name
- DS-F (NCT07118189)
- Testing
- N95 masks and indoor air cleaner
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
Asthma, Pollution; Exposure
Residential Ventilation Systems and Filtration for Asthma Control in Adults
The goal of this study was to investigate the effectiveness of three common approaches to upgrading residential mechanical ventilation systems in existing homes for improving asthma-related health outcomes, reducing indoor…
- Trial name
- NCT06098287
- Testing
- Residential mechanical ventilation system (Exhaust), Residential mechanical ventilation system (CFIS) and air filtration upgrades, Residential mechanical ventilation system (ERV) and air filtration upgrades
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Illinois Institute of Technology
Cardiac Arrhythmias
Correlations Between Arrhythmias and Air Pollution in Patients With Pacemaker and ICD
It is a clinical, observational study to evaluate the correlations among arrhythmias, climatic variables and air pollution in patients with pacemaker and implantable defibrillator (ICD), followed by remote monitoring.
- Trial name
- ARIA (NCT01723761)
- Where
- 9 sites in Italy
- Volunteers
- 473 people
- Sponsor
- Effect Group, Italy
Vascular Function
Effect of Woodsmoke on Vascular Function
Exposure to air pollution is a well established risk factor for the development of heart disease. Firefighters are exposed to excess air pollution in the form of wood smoke during the extinguishing of forest or woodland fires.
- Trial name
- FIREWOOD (NCT01495325)
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Respiratory Disease
Luftibus in the School: a Study on the Respiratory Health of Schoolchildren.
This study assessed the respiratory health of schoolchildren from the canton of Zurich by combining self-reported information on respiratory symptoms with lung function test results and air pollution measurements.
- Trial name
- LUIS (NCT03659838)
- Where
- Switzerland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Spirometry
The INTERvening for LUNG Health Trial
This research study is being done to find out whether a community health volunteer-delivered, multi-component program can improve lung health for people at risk of chronic respiratory diseases (such as asthma or COPD) in…
- Trial name
- INTERLUNG (NCT07540000)
- Testing
- Community health worker-delivered multi-component respiratory health intervention
- Where
- 2 sites in United States, Nepal
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Cardiovascular (CV) Risk
Democratizing Access to Cleaner Residential Air
The purpose of this research study is to determine whether the use of in-home air filtration to reduce exposure to air pollution benefits health.
- Trial name
- DACRA (NCT07629518)
- Testing
- Portable air purifiers with HEPA filtration
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Douglas Brugge
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Cancer
- Trial name
- LoF (NCT07536178)
- Testing
- Woodsmoke (Lodgepole Pine) exposure, Filtered air exposure
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oxidant Imbalance, Pulmonary Function
In Utero Household Air Pollution Exposure and Lung Development in Ghana
Household air pollution from cook stoves using solid fuels dominates total population air pollution exposures. Females and young children are disproportionately affected as they either perform or are present for the majority of…
- Trial name
- NCT02200289
- Where
- Ghana
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Exposure to Pollution, Heart Failure
Effects of Air Pollution Exposure Reduction by Filter Mask on Heart Failure
Exposure to air pollution is associated with increase in cardiovascular morbidity and mortality. Controlled human exposure studies have demonstrated impaired vascular function and heart rate variability on healthy volunteers.
- Trial name
- NCT01960920
- Testing
- Filtered diesel exhaust, Unfiltered diesel exhaust, Clean air
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Heat Strain
Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED-CLIM OW (NCT07634952)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Greece, Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Physical Inactivity, Pollution; Exposure
Air Pollution and Physical Activity Study
This is a small pilot intervention tria lfor exercise and air pollution.
- Trial name
- PARC (NCT06386055)
- Testing
- Active exercise
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Coronary Heart Disease, Cardiovascular Diseases
Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study
This pilot study (n=20) is a prospective evaluation of the implementation of an indoor air pollution intervention among adults 55 years of age or older.
- Conditions
- Coronary Heart Disease, Cardiovascular Diseases, Environmental Exposure
- Trial name
- NCT06384625
- Testing
- AIRWISE
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Montana
Occupational Exposure
Air Quality Monitoring and Health Surveillance of Workers in the Photocopier Units
To monitor air quality in selected photocopier units and to assess the health status of workers who are exposed to emissions from photocopiers.
- Trial name
- NCT01289184
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Avinashilingam Deemed University
Air Pollution Exposure
Voices Illuminating Solutions for Outdoor Workers' Needs and Safety
The goal for this multidisciplinary randomized controlled trial (RCT) is to actively and meaningfully engage outdoor workers (can include agricultural workers, construction workers, landscaping, wildland firefighters, fire…
- Trial name
- VISIONS (NCT07713264)
- Testing
- Receive education on heat and air quality health risks, Participate in Photovoice and climate health risk education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Endoscopy, Gastrointestinal
Air Quality Check in Gastrointestinal Endoscopy Unit
Air pollution sources in indoor area are one of the main factors for reducing indoor air quality of locations. A gastrointestinal endoscopy unit consists of the following area: procedural, recovery areas, and area for a…
- Trial name
- NCT03724565
- Testing
- Method of endoscopic procedure
- Where
- South Korea
- Volunteers
- 4,320 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital