Clinical trials: Airway Device
Airway Management, Infant ALL
Defining the 'Sniffing Position" in Infants and Toddlers - A Pilot Study
The "sniffing position" is widely accepted as a favorable position for direct laryngoscopy (DL) in both pediatric and adult patients.
- Conditions
- Airway Management, Infant ALL, Children, Only, Endotracheal Intubation
- Trial name
- NCT04410289
- Testing
- Airway positioning per specified protocol followed by Direct Laryngoscopy and Endotracheal Intubation, Airway positioning per provider preference followed by Direct Laryngoscopy and Endotracheal Intubation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Nocturnal Hypoventilation, Obesity
Prevalence of Nocturnal Hypoventilation in Obese Subjects Fiited With Continuous Positive Airway Pressure for Obstructive Sleep Apnea / Hypopnea Syndrome
CAPNOSOH study is a single-center study conducted at Toulouse University Hospital, aiming to estimate the prevalence of obese and apneic subjects maintaining nocturnal hypoventilation under continuous positive airway pressure…
- Conditions
- Nocturnal Hypoventilation, Obesity, Sleep Apnea Hypopnea Syndrome
- Trial name
- CAPNOSOH (NCT07152990)
- Testing
- Transcutaneous Oxy-Capnography, Quality of life questionnaires, Arterial gasometry
- Where
- France
- Volunteers
- 139 people
- Sponsor
- University Hospital, Toulouse
Cuff, Airway Edema
Determining Optimal Cuff Volume in Pediatric Patients
Background and Aim: Cuffed endotracheal tubes with appropriate size, good cuff design and cuff pressure monitoring in pediatric patients can be used safely without increasing airway morbidity.
- Conditions
- Cuff, Airway Edema, Children, Only, Tracheal Intubation Morbidity
- Trial name
- NCT04948359
- Testing
- Group I (The patients intubated with cuffed ETT of ID number 4.5), Group II (The patients intubated with cuffed ETT of ID number 5.0), Group III ( The patients intubated with cuffed ETT of ID number 5.5)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Asthma
Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics
The aim of the study is to test the hypothesis that the allergic airway inflammation in asthmatic patients will be enhanced after exposure to ultrafine particles (UFP).
- Trial name
- NCT00527462
- Testing
- Bronchoscopy, Exposure to ultrafine carbon black particles
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Healthy
Alcohol Exposure and Airway Hyperresponsiveness
Alcohol has consequences including increased risk for upper respiratory tract infections, pneumonia, acute respiratory distress syndrome (ARDS), and alcohol-induced asthma.
- Trial name
- NCT00990275
- Testing
- ethanol
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Influence of Mouthpiece Design on Upper Airway Geometry
Evaluation With Scans and Pharyngometry of the Possible Changes in Upper Airway Geometry Induced by Using Different Mouthpieces.
In this study the possible changes in upper airway geometry induced by variations in the characteristics of the mouthpieces of inhalers will be evaluated with functional respiratory imaging (FRI) and Pharyngometry.
- Trial name
- NCT01592929
- Testing
- Magnetic Resonance imaging, Pharyngometry, Computed Tomography scan
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC)
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or…
- Conditions
- Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
- Trial name
- DISCRETE AF (NCT07220525)
- Testing
- HGNS Use Randomized Instructions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Mask Ventilation, Airway Obstruction Upper
The Articulated Oral Airway as an Aid to Mask Ventilation
The Articulating Oral Airway (AOA) is a novel oral airway which actively displaces the tongue, allowing for a greater cross-sectional area for mask ventilation.
- Conditions
- Mask Ventilation, Airway Obstruction Upper, Airway Management
- Trial name
- NCT03144089
- Testing
- Articulated Oral Airway, Guedel oral airway (active comparator)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ron Abrons
Obesity
Effect Of Obesity On Ozone-Induced Airway Inflammation
The purpose of this study is to compare the effect of ozone exposure on airway reactivity and inflammation in obese vs. non-obese adults.
- Trial name
- OBOZ (NCT00839943)
- Testing
- ozone, 0.4 ppm
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Laryngeal Cancer, Difficult Airway
Validation of End-to-End Difficult Airway Pathway Planning Algorithm (EAP-LC)
Patients with laryngeal cancer often present with varying degrees of airway narrowing or anatomical distortion, making airway management particularly challenging.
- Trial name
- NCT07324317
- Testing
- No Interventions
- Volunteers
- 70 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Respiratory Distress Syndrome
Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants
Premature babies often need help breathing for a longer period of time. Traditionally, this is done with a breathing aid called NCPAP (nasal continuous positive airway pressure).
- Trial name
- MASTER (NCT05908227)
- Testing
- NHF high, NHF low, NCPAP
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Small Airway Dysfunction
Extrafine ICS/LABA Versus As-Needed SABA for Small Airway Dysfunction in Symptomatic Patients With Preserved Spirometry
This study evaluates whether 4 weeks of extrafine inhaled corticosteroid/long-acting β2-agonist (beclomethasone dipropionate/formoterol fumarate, BDP/FOR) therapy improves clinical, physiological, and type 2 inflammatory outcomes…
- Trial name
- NCT07809555
- Testing
- Beclomethasone dipropionate/formoterol fumarate (extrafine), Salbutamol
- Where
- Taiwan
- Volunteers
- 93 people
- Sponsor
- Yi-Han Hsiao
Asthma Acute, Asthma Exacerbation
45th Multicenter Airway Research Collaboration
The study is a randomized controlled trial on the effect of emergency department initiation of Airsupra on acute asthma "recurrence" at 3 months and other related outcomes (acute asthma relapse, asthma control).
- Conditions
- Asthma Acute, Asthma Exacerbation, Asthma, Asthma Control Level
- Trial name
- MARC-45 (NCT07166939)
- Testing
- Airsupra
- Where
- United States
- Volunteers
- 1,860 people
- Sponsor
- Massachusetts General Hospital
Lung Injury, Acute
a Study Conducted About a New Mode of Ventilation in Laparoscopic Surgeries
Carbon dioxide insufflations of abdomen are integral part of laparoscopic operations in minimally invasive surgery era. It does cause splinting effect on diaphragm movement and set it high inside thoracic cavity too.
- Trial name
- NCT03637530
- Testing
- inverse ratio ventilation
- Volunteers
- 128 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Asthma, Chronic Obstructive Pulmonary Disease
Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma
Asthma and COPD are characterized by airway narrowing. The most potent, physiological mechanism leading to bronchodilation is taking a deep inspiration.
- Trial name
- NCT00279136
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Hypoxia, Hypercapnia
Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange
For performing transnasal humidified rapid insufflation ventilatory exchange (THRIVE), jaw-thrust maneuver have to maintain to make sure the airway open and the CO2 clearance during apnoea.
- Trial name
- NCT03741998
- Testing
- Nasopharyngeal airway
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Obstructive Sleep Apnea, Obesity
Sibutramine Versus Continuous Positive Airway Pressure (CPAP)in Obstructive Sleep Apnea (OSA) Patients
The primary objective of this study is to observe if Sibutramine is effective in improving the symptoms and signs of sleep apnea in obese patients.
- Conditions
- Obstructive Sleep Apnea, Obesity, Hypertension
- Trial name
- NCT00729963
- Testing
- Sibutramine, CPAP
- Volunteers
- 45 people
- Sponsor
- Laval University
Asthma
Effects of Macrolides on Asthma Control
Asthma is a common disease in Westernised societies, affecting up to 10% of the population. Corticosteroids are the most effective treatment for asthma but the therapeutic response varies considerably between individuals.
- Trial name
- NCT00852579
- Testing
- Azithromycin
- Where
- 2 sites in United Kingdom
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Euan J Cameron
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two…
- Trial name
- NCT02249143
- Testing
- CPAP and room air
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Acute Respiratory Distress Syndrome
A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDS
Animal experimentals have shown that the more physiology-driven airway pressure release ventilation (APRV) methodologies in ARDS may significantly improve alveolar recruitment and gas exchange, increased homogeneity, and…
- Trial name
- NCT03549910
- Testing
- APRVplus protocol, Low tidal volume ventilation
- Where
- China
- Volunteers
- 840 people
- Sponsor
- West China Hospital