Clinical trials: Airway Disease
Cystic Fibrosis, Asthma
Project 2 Airway Potential Hydrogen (pH) in Asthma
This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug.
- Conditions
- Cystic Fibrosis, Asthma, Severe Persistent Asthma, Healthy
- Trial name
- NCT03617718
- Testing
- Glycine Buffer
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- Case Western Reserve University
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal)
Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study
The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS).
- Conditions
- Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Respiratory Distress Syndrome of Newborn
- Trial name
- NCT07550218
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Smoking, COPD
Integrative-omics of the Disordered COPD Small Airway Epithelium
We aim to use an integrated network systems approach to analyze certain existing small airway epithelium (SAE) omic data sets at the genetic, epigenetic (methylation), gene expression, microRNA and metabolomic levels, to develop…
- Trial name
- NCT02183818
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Obesity Hypoventilation Syndrome
Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome
The purpose of this study is to investigate the evolution of daytime partial pressure of carbon dioxide in the blood (PaCO2) after 6 weeks of noninvasive ventilation-pressure support ventilation (NIV-PSV) with target volume…
- Trial name
- OVO (NCT01104610)
- Testing
- Breas Vivo 40
- Where
- 2 sites in France
- Sponsor
- Breas Medical S.A.R.L.
Intubation Complication, Hoarseness
Thermosoftening of Double-lumen Tube for Airway Exchanger Catheter
The purpose of this study is to investigate the effect of double-lumen tube thermal-softening before intubation on the success rate of tube exchange by airway exchange catheter.
- Conditions
- Intubation Complication, Hoarseness, Sore Throat
- Trial name
- NCT03846713
- Testing
- non-thermosoftening, thermosoftening
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Seoul National University Hospital
Hyperreactive Airway Disease
Methacholine Challenge Test (MCT) in Healthy Adults
Knowledge of Methacholine Challenge Test (MCT) and impedance Oscillometry (IOS) is limited. Only three studies have included adult patients, and none of these with healthy controls.
- Trial name
- NCT06509659
- Testing
- Methacholine Challenge Test
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Nasal Alar Collapse, Bilateral
Study of Polyester Implants for the Treatment of External Nasal Valve Collapse (NVC)
The purpose of this study is to research a polyester polyethylene terephthalate (PET) implant for the treatment of external nasal valve collapse (NVC).
- Trial name
- NVC (NCT00729781)
- Testing
- Polyester Implants
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- Medtronic Xomed, Inc.
Bronchiectasis Adult
Airway Clearance Technique of Oscillation and Lung Expansion in Bronchiectasis
The goal of this prospective randomized controlled trial is to explore the efficacy and safety of Oscillation and Lung Expansion-a airway clearance technology-in bronchiectasis.
- Trial name
- NCT06393257
- Testing
- Oscillation and Lung Expansion, Postural drainage, Anti-infective therapy
- Where
- 3 sites in China
- Volunteers
- 96 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Bile Duct Disorder, Endocrine Pancreas Disorder
Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct Disorders
This trial determines the feasibility of Laryngeal Mask Airway Gastro (Laryngeal Mask Airway) when used on patients who are undergoing endoscopic retrograde cholangiopancreatography for pancreas and bile duct disorders.
- Trial name
- NCT03775681
- Testing
- Endoscopic Retrograde Cholangiopancreatography, Interview, Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Sinusitis, Nasal Obstruction
Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgery
The purpose of the research is to assess the effectiveness of a dose of intravenous tranexamic acid (TXA) given intraoperatively to reduce postoperative bleeding after endoscopic sinus or nasal surgery (e.g.
- Conditions
- Chronic Sinusitis, Nasal Obstruction, Turbinate; Hypertrophy Mucous Membrane, Deviated Nasal Septum - Congenital
- Trial name
- NCT04754230
- Testing
- Tranexamic Acid 1,000 Mg/10 mL (100 Mg/mL) INTRAVEN VIAL (ML)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Acute Respiratory Distress Syndrome
Airway Pressure Release Ventilation (APRV) Protocol Early Used in Acute Respiratory Distress Syndrome
The aim of this study is to assess the effects and safety of the early application of BILEVEL-APRV protocol and conventional ventilation strategy that used low tidal volume and adequate PEEP level in ARDS patients .
- Trial name
- NCT02639364
- Testing
- Nellcor Puritan Bennett 840 ventilator system
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Cervical Pain, Cervical Disease
The Correlation of the Cervical Symptoms With Intubation Quality and Airway Assessment
Cervical spine disorders can cause neck pain with or without neurological dysfunction. The most common cause of acute and chronic neck pain is cervical degenerative changes.
- Trial name
- NCT05188807
- Testing
- Airway ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ankara University
Xerostomia
NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy
To assess whether the daily use of NeutraSal will prevent or reduce dry mouth in patients undergoing CPAP therapy for OSAS and improve CPAP compliance
- Trial name
- NCT02107300
- Testing
- NeutraSal
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical University of South Carolina
General Anesthesia
Assessment of Facial Measurements, the Length of Mouth Corner-mandible Angle and Incisors-mandible Angle, for Determining the Proper Sizes of Oropharyngeal Airway
The purpose of this study is to assess the facial measurements for determining the proper sizes of oropharyngeal airway. Investigators hypothesized that the length between incisors and mandible angle is more appropriate to…
- Trial name
- NCT01945411
- Testing
- the length between incisor and mandible angle, the length between mouth corner-mandible angle
- Where
- South Korea
- Volunteers
- 113 people
- Sponsor
- Yonsei University
Respiratory Distress Syndrome, Newborn
Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome
In this study, newborn babies with respiratory distress syndrome (RDS), receiving oxygen via nasal continuous airway pressure (CPAP) modalities, and needing surfactant treatment will be randomized to standard delivery of…
- Trial name
- NCT02164734
- Testing
- Endotracheal intubation, Laryngeal mask airway, remifentanil
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Albany Medical College
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
"Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme"
The CALMDOWN trial is a prospective, open-label, multicenter, comparative, controlled trial randomizing patients who received near apneic ventilation vs usual care on ECMO (ultra-protective lung ventilation).
- Trial name
- CALMDOWN (NCT06814340)
- Testing
- ECMO + near apneic ventilation, ECMO + ultra-protective lung ventilation
- Where
- 11 sites in France
- Volunteers
- 280 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
Comparison of two asthma treatments by lung function measures.
- Trial name
- NCT00169546
- Testing
- Salmeterol/fluticasone propionate, Fluticasone propionate
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 64 people
- Sponsor
- GlaxoSmithKline
Asthma, Cystic Fibrosis
FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis
Background By means of measurements of series of non-invasive inflammatory markers in exhaled breath (condensate), a reflection of inflammatory processes and oxidative stress, can be obtained.
- Trial name
- NCT00404859
- Where
- 4 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Maastricht University Medical Center
Obstructive Sleep Apnea
Anxiety and Depression In Patients With Obstructive Sleep Apnoea Before and After Continuous Positive Airway Pressure
Continuous positive airway pressure (CPAP) is the gold-standard treatment for obstructive sleep apnoea (OSA), the most common sleep-disordered breathing in the overall population.
- Trial name
- ADIPOSA (NCT04104880)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Granada
Obstructive Sleep Apnea
Impact of Automated Education and Follow-up Mechanisms on Patient Engagement
The primary and well-known challenge with continuous positive airway pressure (CPAP) is the incomplete adherence of patients to this therapy.
- Trial name
- EmmiUSleep (NCT02279901)
- Testing
- Telemedicine Education, IVR
- Where
- United States
- Volunteers
- 1,873 people
- Sponsor
- Kaiser Permanente
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