Clinical trials: Airway Morbidity
Atrial Fibrillation, Obstructive Sleep Apnea
The Efficacy of PAP Therapy on Reducing AF Recurrence in Patients With Morbidity of OSA
This study aims to test the effectiveness of positive airway pressure therapy on reducing clinical failure after rhythm control treatment and restoring with regular heart beat in atrial fibrillation patients with obstructive…
- Trial name
- AFOSA (NCT04519489)
- Testing
- PAP therapy with telemonitoring, AF standard management and OSA general care
- Where
- 2 sites in China
- Volunteers
- 129 people
- Sponsor
- Philips (China) Investment CO., LTD
Airway Morbidity
Endotracheal Tube Versus Laryngeal Mask Airway for Esophagogastroduodenoscopy
Esophagogastroduodenoscopy (EGD) is a relatively common procedure in pediatric patients undergoing evaluation for various gastrointestinal ailments.
- Trial name
- NCT01936662
- Testing
- LMA, ETT
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Indiana University
Airway Morbidity
Multicenter Study of EasyTube® Compared to Endotracheal Tube in General Anesthesia
Evaluation of the EzT in comparison with the endotracheal tube (ETT) for its use during general anesthesia.
- Trial name
- EasyTube (NCT02359630)
- Testing
- EasyTube, Endotracheal tube
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Asthma
Breathing Versus Aerobic Exercises on Asthma Control
Background: Asthma is a chronic inflammatory airway disease characterized by reversible obstruction, inflammation and hyperresponsiveness to different stimulus.
- Trial name
- NCT02065258
- Testing
- Breathing exercise, Aerobic exercise
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo General Hospital
Airway Morbidity
Non-Crossover Study of the LMA Protector Versus Ambu AuraGain
The LMA ProtectorTM is a new extraglottic airway device which brings together features of both the LMA ProSealTM (high seal cuff, gastric access and bite block - to facilitate ventilation, airway protection and airway…
- Trial name
- NCT02820792
- Testing
- function tests, LMA ProtectorTM, Ambu AuraGainTM
- Where
- 2 sites in Switzerland
- Volunteers
- 96 people
- Sponsor
- Schulthess Klinik
Lung Function
eCPAP Follow-up at School Age
The purpose of the study is to learn more about extended continuous positive airway pressure (eCPAP) in preterm infants that may be helpful for lung health.
- Trial name
- NCT07860931
- Testing
- Extended CPAP (eCPAP)
- Volunteers
- 95 people
- Sponsor
- Cynthia McEvoy
Sleep Apnea, Cardiovascular Disease
Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea to Prevent Cardiovascular Disease
Obstructive Sleep Apnea (OSA) is a condition in which a person stops breathing for several seconds at a time due to relaxation of the throat muscles. This can occur many times during sleep.
- Trial name
- SAVE (NCT00738179)
- Testing
- Continuous Positive Airway Pressure (CPAP), Standard care
- Where
- 5 sites in Australia, Brazil and 3 more
- Volunteers
- 2,500 people
- Sponsor
- Adelaide Institute for Sleep Health
Device Induced Injury, Necrosis, Pressure
Mucosal Pressure of the Laryngeal Mask Airway Supreme Versus the i-Gel in Paralyzed Anesthetized Female Patients
In the following randomized non-crossover study, the investigators test the hypothesis that directly measured mucosal pressure differ between the laryngeal mask airway (LMA) Supreme and the i-Gel in paralyzed anesthetized…
- Conditions
- Device Induced Injury, Necrosis, Pressure, Complication of Device Insertion, Airway Morbidity
- Trial name
- NCT01367678
- Testing
- Laryngeal Mask Airway Supreme, i-Gel extraglottic airway device
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 30 people
- Sponsor
- Schulthess Klinik
Anesthesia Insertion Complication, Airway Morbidity
The Effectiveness of Foley Airway Stylet Tool on Proseal LMA Insertion
Due to its soft cuff easily folded to impede ProSeal LMA insertion, many tools are developed. The aim of the study is to investigate the efficiency of ProSeal LMA insertion guided by a soft, direct optical Foley airway stylet…
- Trial name
- NCT02048657
- Testing
- Foley Airway Stylet Tool, introducer-tool
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Airway Morbidity, Team Efficacy
A Novel Intuitive Airway Trolley for Quick Decision-making in Simulated Unexpected Difficult Airway Situations: Evaluation and Comparison to the Existing Airway Trolley
The goal of this study is to analyze the impact of color-coded labeling and cognitive visual aids of a novel airway trolley on the performance of participants in a simulated unexpected difficult airway scenario.
- Conditions
- Airway Morbidity, Team Efficacy, Intubation; Difficult or Failed, Human Factors
- Trial name
- Airway-to-Go (NCT07076511)
- Testing
- Scenario "unexpected difficult airway"
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Johannes Gutenberg University Mainz
Airway Morbidity
Crossover Study of the LMA SupremeTM vs Ambu-Aura GainTM
The Ambu-Aura GainTM is a new extraglottic airway device which brings together features of both the LMA ProSealTM (high seal cuff, gastric access and bite block - to facilitate ventilation, airway protection and airway…
- Trial name
- NCT02458794
- Testing
- function tests, LMA SupremeTM, Ambu-Aura GainTM
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 200 people
- Sponsor
- Schulthess Klinik
Airway Morbidity
Bronchoscopic Endotracheal Intubation Through a SAD - Physician Performance
Prospective observational study with the primary objective is to assess technical competence in anaesthesiology specialists who perform bronchoscopic endotracheal intubation through a supraglottic airway device (SAD), by using a…
- Trial name
- NCT04743440
- Testing
- Bronchoscopic endotracheal intubation through a supraglottic airway device
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Hypoxia, Endoscopy
Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
This study is a randomized controlled trial comparing oxygen delivery by nasal mask with continuous positive airway pressure versus standard care (nasal cannula or standard facemask) during propofol-based sedation for…
- Conditions
- Hypoxia, Endoscopy, Anesthesia Morbidity
- Trial name
- NCT03369197
- Testing
- Nasal Mask, Control: Nasal Cannula
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Airway Morbidity
Evaluation of Techniques for Tracheal Tube Exchange in Standard and Critical Care Patients
A randomized controlled study to evaluate different Techniques and Approachs for the Exchange of a tracheal tube or supraglottic airway device in a Simulator
- Trial name
- TUBE (NCT04158271)
- Testing
- Prone Position, Laryngeal tube, Endotracheal tube Leackage
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Airway Morbidity
Comparison of Ease of I-gel Insertion With Two Different Techniques in Adults
Study will evaluate the I-gel airway device standard insertion technique versus interventional (modified jaw thurst) insertion technique in adult patients.
- Trial name
- NCT04109898
- Testing
- Supraglottic airway device (I-gel) insertion
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Infant, Premature, Diseases, Airway Morbidity
Optimising Ventilation in Preterms With Closed-loop Oxygen Control
Many premature infants require respiratory support in the newborn period. Mechanical ventilation although life-saving is linked to complications for the lungs and other organs and its duration should be kept to a minimum.
- Conditions
- Infant, Premature, Diseases, Airway Morbidity, Mechanical Ventilation Complication
- Trial name
- NCT05030337
- Testing
- Closed-loop automated oxygen control (Oxygenie, SLE 6000)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- King's College Hospital NHS Trust
Airway Morbidity, Cognitive and Attention Disorders and Disturbances
Short-term Health Benefits of Using Fresh Air Filtration System in Classroom
A randomized crossover trial will be conducted in 90 primary school children in 3 classrooms in Shanghai, China. The effects of fresh air ventilation/filtration system, fresh air ventilation system with no filtration and natual…
- Conditions
- Airway Morbidity, Cognitive and Attention Disorders and Disturbances, Oxidative Stress
- Trial name
- NCT03788330
- Testing
- Fresh air system with filtration
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Fudan University
Asthma Attack, Lung Function
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC).
- Conditions
- Asthma Attack, Lung Function, Airway Inflammation
- Trial name
- NCT07116460
- Testing
- Austin Air Cleaner
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Airway Remodeling
Observational Study With Investigation of Two Second Generation Laryngeal Masks
In a observational study the second-generation laryngeal masks LMA Supreme and Ambu AuraGain are investigated.
- Trial name
- OSSGA (NCT02566291)
- Testing
- Success
- Where
- Germany
- Volunteers
- 364 people
- Sponsor
- Johannes Gutenberg University Mainz
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp