Clinical trials: Airway Morbidity
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Hypertension, Sleep Apnea, Obstructive
Morbidity in Patients With Hypertension and Obstructive Sleep Apnea
MORPHEOS is a multicenter, randomized, unblinded study, for patients diagnosed with uncontrolled hypertension and at least one antihypertensive medication.
- Trial name
- MORPHEOS (NCT02270658)
- Testing
- CPAP
- Where
- 5 sites in Brazil
- Volunteers
- 123 people
- Sponsor
- University of Sao Paulo General Hospital
Airway Morbidity, Covid19
Feasibility of the Infra-Red Illumination for Facilitation of Video Scope-tracheal Intubation
Airway securing through the placement of an endotracheal tube continues to be the definitive and the global standard management.
- Conditions
- Airway Morbidity, Covid19, Trachea
- Trial name
- NCT04991545
- Testing
- Application of Infrared (Active IRD/ IRRIS) device
- Where
- Qatar
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Airway Morbidity, Intubation Complication
Comparison of Double Lumen Tube Placement Techniques
The purpose of this study is to compare three different standard of care methods of double-lumen endobronchial tube (DLT) placement in patients who are scheduled to have thoracic surgery in which lung isolation is required.
- Conditions
- Airway Morbidity, Intubation Complication, Tracheal Intubation Morbidity, Anesthesia Intubation Complication
- Trial name
- NCT02495259
- Testing
- ZU-bend stylet, GlideScope, GlideRite stylet
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Emory University
Airway Morbidity, Intubation Complication
Repositioning Method for Left-sided Double Lumen Tubes
The purpose of this study is to devise repositioning method of a left-sided double lumen tube into left mainstem bronchus in case of misplacement into right mainstem bronchus.
- Trial name
- NCT01371773
- Testing
- repositioning method for left-sided double lumen tubes
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Cuff, Airway Edema
Determining Optimal Cuff Volume in Pediatric Patients
Background and Aim: Cuffed endotracheal tubes with appropriate size, good cuff design and cuff pressure monitoring in pediatric patients can be used safely without increasing airway morbidity.
- Conditions
- Cuff, Airway Edema, Children, Only, Tracheal Intubation Morbidity
- Trial name
- NCT04948359
- Testing
- Group I (The patients intubated with cuffed ETT of ID number 4.5), Group II (The patients intubated with cuffed ETT of ID number 5.0), Group III ( The patients intubated with cuffed ETT of ID number 5.5)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Airway Remodeling
Observational Study With Investigation of Two Second Generation Laryngeal Masks
In a observational study the second-generation laryngeal masks LMA Supreme and Ambu AuraGain are investigated.
- Trial name
- OSSGA (NCT02566291)
- Testing
- Success
- Where
- Germany
- Volunteers
- 364 people
- Sponsor
- Johannes Gutenberg University Mainz
Airway Morbidity
Comparative Evaluation of Three Airway Maneuvers in the Unconscious Apneic Person
One-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver are three common airway management maneuvers.
- Trial name
- NCT02104453
- Testing
- airway maneuver
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Sleep Apnea, Hypertension
Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime Sleepiness
The objective of the study is to evaluate the effect of CPAP over the incidence of cardiovascular events and diagnosis of arterial hypertension in patients with sleep apnea.
- Conditions
- Sleep Apnea, Hypertension, Cardiovascular Diseases
- Trial name
- NCT00127348
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
High Flow Oxygen in Rapid Sequence Induction, Airway Morbidity
High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients
High flow oxygen results in better oxygenation in emergency cases needing rapid sequence induction for anaesthesia. Secondary outcome measure is time for any desaturation.
- Trial name
- THRIVE/RSI 1 (NCT02777840)
- Testing
- face mask oxygen, High flow oxygen
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Thyroid, Airway Morbidity
Influenced the Type of Laryngoscopy the Intraoperative Nerve Monitoring During Thyroid Surgery
A randomized controlled prospective study of laryngoscopy and evaluation of the Intraoperative nerve monitoring during thyroid surgery comparing direct laryngoscopy and the C-MAC videolaryngoscope.
- Trial name
- LiON (NCT02943980)
- Testing
- CMAC Videolaryngoscope, Macintosh Laryngoscope
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Johannes Gutenberg University Mainz
Cystic Fibrosis in Children, Respiratory Bacterial Infection
Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis
Cystic fibrosis (CF) is the most common hereditary life-threatening condition in Belgium. Because of a dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) channel, chloride is unable to move to the cell…
- Conditions
- Cystic Fibrosis in Children, Respiratory Bacterial Infection, Respiratory Viral Infection, Inflammation Lungs
- Trial name
- NCT06188988
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Antwerp
Airway Morbidity
A New Insertion Technique for Laryngeal Mask Airway
A laryngeal mask airway ("LMA") is an airway device that is commonly used and placed under general anesthesia to facilitate ventilation of the patient's lungs while anesthetized.
- Trial name
- NCT01749033
- Testing
- Group 1 Classic, Group 2 pre-inflated, Group 3 ELL-PIC
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Northwestern University
Airway Morbidity, Nurse's Role
Self-Directed Versus Traditional Clinical Learning Model on Nurses' Airway Management Competencies
Effect of Self-Directed Versus Traditional Clinical Learning Model on Nurses' Airway Management Competencies and Patients' Airway Related Incidents Introduction Airway crisis situations in ICUs (Intensive Care Units) are common…
- Conditions
- Airway Morbidity, Nurse's Role, Airway Obstruction, Nurse's Scope of Practice
- Trial name
- SDLMvsTCLM (NCT04244565)
- Testing
- Self-directed model of clinical learning for nurses
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infant, Premature, Diseases, Airway Morbidity
Optimising Ventilation in Preterms With Closed-loop Oxygen Control
Many premature infants require respiratory support in the newborn period. Mechanical ventilation although life-saving is linked to complications for the lungs and other organs and its duration should be kept to a minimum.
- Conditions
- Infant, Premature, Diseases, Airway Morbidity, Mechanical Ventilation Complication
- Trial name
- NCT05030337
- Testing
- Closed-loop automated oxygen control (Oxygenie, SLE 6000)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- King's College Hospital NHS Trust
Airway Morbidity, Anaesthesia
I-gel vs LMA Supreme in Laparoscopic Gynecological Surgery
To compare the effects of i-gel and Laryngeal mask airway Supreme (LMA-Supreme) on ventilation parameters and surgical view during Trendelenburg Position laparoscopic gynecological surgery in cases administered positive pressure…
- Trial name
- NCT02923427
- Testing
- Laryngeal mask Supreme Evaluation, i-gel Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Dokuz Eylul University
Lung Function
eCPAP Follow-up at School Age
The purpose of the study is to learn more about extended continuous positive airway pressure (eCPAP) in preterm infants that may be helpful for lung health.
- Trial name
- NCT07860931
- Testing
- Extended CPAP (eCPAP)
- Volunteers
- 95 people
- Sponsor
- Cynthia McEvoy
Infant, Newborn, Diseases, Airway Morbidity
Integrated Prediction of Extubation Outcome by the Spontaneous Breathing Trial in Newborn Infants
Prolonged mechanical ventilation (MV) is associated with significant adverse effects in newborn infants and clinicians aim at its minimum possible duration.
- Trial name
- NCT03956511
- Testing
- Spontaneous Breathing Trial
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Ourania Kaltsogianni
Anxiety, Depression
Effect of Aerobic Training on Asthmatic Patients
The investigators hypothesize that aerobic training can reduce anxiety, depression and airway inflammation and those benefits may be related to changes in autonomic system.
- Conditions
- Anxiety, Depression, Airway Inflammation
- Trial name
- NCT00989365
- Testing
- Aerobic training
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Anesthesia, Airway Morbidity
Preoxygenation Using High Flow Oxygen : Efficacy and Tolerance in Healthy Volunteers
High flow nasal cannula oxygen has been proposed to perform preoxygenation in patients with acute respiratory failure requiring orotracheal intubation in intensive care units.
- Conditions
- Anesthesia, Airway Morbidity, Safety Issues
- Trial name
- PreOx-OHD (NCT03399695)
- Testing
- preoxygenation
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen