Clinical trials: Airway Pressure
Pompe Disease
CPAP for Infantile Pompe Disease
Patients with infantile onset Pompe disease will be trained with continuous positive airway pressure to see if hypernasality can be improved.
- Trial name
- NCT02405624
- Testing
- continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea
The Continuous Positive Airway Pressure Effect on Rho-associated Coiled-coil Containing Kinases Activity.
The ROCK (Rho-associated coiled-coil containing kinases) play a critical role in the pathogenesis of cardiovascular diseases and left ventricle hypertrophy (LVH).
- Trial name
- NCT05014529
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea
Cardiovascular Impact of Obstructive Sleep Apnea Treatment in Normotensive Patients
Recent evidences suggest that obstructive sleep apnea (OSA) can contribute to cardiovascular disease even in the absence of hypertension.
- Trial name
- OSA-NORMO (NCT00741520)
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Preterm Infants, Nasal Continuous Positive Airway Pressure
Effect of Therapeutic Touch and Mother's Voice on Pain and Comfort Level During Nasal CPAP Application
Aim: This study was conducted to evaluate the effects of Therapeutic Touch and Mother's Voice on pain and comfort levels of preterm infants during nasal CPAP application.
- Conditions
- Preterm Infants, Nasal Continuous Positive Airway Pressure, Pain Management
- Trial name
- CPAP (NCT05577793)
- Testing
- Mother's Voice, Therapeutic Touch, Mother's Voice +Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Ayşe Belpınar
Myocardial Revascularization
Interventional Effects on Myocardial Revascularization Post-surgical Patients
The aim is to evaluate the effectiveness of physical exercise on a cycle ergometer combine with CPAP in the postoperative period after myocardial revascularization
- Trial name
- NCT04790656
- Testing
- Conventional Therapy, Cycle ergometer combine with CPAP
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Apnoeic Oxygenation
Positive Airway Pressure Under Apnoeic Oxygenation With Different Flow Rates in Nasal Cannula Therapy
The main objective of this explorative observational study is to investigate the pressures in infraglottic airway and the pharynx provided by THRIVE , using flows ranging from 1l/min to 80 l/min, in patients hospitalized for…
- Trial name
- PAPUA-Flow (NCT03738722)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obstructive Sleep Apnea, Cardiovascular Disease
Metabolic Profiling in Patients With Obstructive Sleep Apnea: From Plasma to Hypoxic Cell Model of Peripheral Monocyte
This three-year project aims to 1. Profile the differentially expressed metabolites in healthy patients with severe Obstructive sleep apnea (OSA) before and after six-month continuous positive airway pressure (CPAP) treatment 2.
- Trial name
- NCT02130050
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation
Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting an estimated 1 in 10 Canadians. Symptoms include persistent shortness of breath, cough and sputum production.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation, Obstructive Sleep Apnea, Hypoventilation
- Trial name
- NCT05623709
- Testing
- Positive airway pressure with continuous positive airway pressure or noninvasive ventilation
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Bronchopulmonary Dysplasia, Prematurity
Impact of Extended CPAP on Bronchopulmonary Dysplasia
The purpose of this pilot study is to compare if keeping infants on CPAP (continuous positive airway pressure) support for an extended period of time until they are 32 weeks corrected gestational age or 1250 grams (approximately…
- Trial name
- NCT05547139
- Testing
- Protocolized weaning of respiratory support
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Stroke
Applicability of Techniques of Lung Expansion
The survival of patients with lesions in the central nervous system is usually accompanied by physical and mental sequelae. These impairments favor the prolonged restriction to the bed, which may contribute with changes in…
- Trial name
- NCT02613832
- Testing
- EPAP, Breath Stacking
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Sleep Apnea Syndromes
Sleep Apnea and Oxidative Stress and Nitric Oxide
Background: Previous studies present contradictory data concerning obstructive sleep apnea syndrome (OSAS), lipid oxidation and nitric oxide (NO) bioavailability.
- Trial name
- NCT00547937
- Testing
- nasal continuous positive airway pressure (CPAP) therapy
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Hypoxia
Oxygen Insufflation in Microlaryngoscopies
The purpose of this project is to evaluate the efficacy of oxygen insufflation (continuous oxygen flow) to keep oxygen saturation (oxygen levels measured with a pulse oximeter [finger device used in medicine]) at 90% or greater…
- Trial name
- NCT04979533
- Testing
- Insufflator oxygen tubing
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase
Optic Nerve Sheath Diameter in Pediatric Patients
Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure.
- Conditions
- Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase, Intubation Complication, Airway Complication of Anesthesia
- Trial name
- NCT05445271
- Testing
- Optic nerve sheath diameter measurement with linear ultrasound
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Laryngeal Mask Airway
Three Inflation Methods of Ambú Auragain™ and Its Adverse Effects
Laryngeal mask is a common supraglottic device (SGD) used in the daily practice for airway management. Consecutive generations have permitted an expansion of its use.
- Trial name
- NCT04795544
- Testing
- Intracuff pressure measurement
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Hypoxia, Endoscopy
Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
This study is a randomized controlled trial comparing oxygen delivery by nasal mask with continuous positive airway pressure versus standard care (nasal cannula or standard facemask) during propofol-based sedation for…
- Conditions
- Hypoxia, Endoscopy, Anesthesia Morbidity
- Trial name
- NCT03369197
- Testing
- Nasal Mask, Control: Nasal Cannula
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea of Adult
Impact of Intermittent Hypoxia on the Function of the Phagocytes
Patients with treatment-naive obstructive sleep apnea (OSA) who need continuous positive airway pressure (CPAP) therapy on clinical basis are included as well as healthy controls without OSA.
- Trial name
- NCT03618719
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sleep Apnea, Obstructive
Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All
Obstructive Sleep apnea(OSA) is a disease with multiple causes, and treatments are very diverse. Patients and doctors have a lot of choices.
- Trial name
- NCT05566860
- Testing
- Positional Therapy, Intraoral Negative Pressure Therapy, Oral Appliances
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Laryngeal Mask Airway
Three Inflation Methods of the Ambú Auraonce™ and Its Adverse Effects
Laryngeal mask airway device (LMA) is a common device used in the daily practice for airway management. Consecutive generations have permitted an expansion of its use, probably because of a rapid increase of ambulatory surgical…
- Trial name
- NCT04769791
- Testing
- intracuff pressure measurement
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz