Clinical trials: Airway Pressure
Pneumonia, Community-Acquired Infections
Helmet Continuous Positive Airway Pressure Versus Oxygen Venturi in Acute Respiratory Failure in CAP: CAPOVeRSO
The purpose of this study is to compare the efficacy of CPAP application by a helmet and O2 administration by a Venturi mask in terms of gas exchanges improvement in patients with acute respiratory failure due to…
- Conditions
- Pneumonia, Community-Acquired Infections, Respiratory Insufficiency, Acute Lung Injury
- Trial name
- CAPOVeRSO (NCT00603564)
- Testing
- Castar Starmed (CPAP) delivered by a helmet
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- University of Milan
Chronic Bronchitis
Comparison Of Blow Bottle Positive Expiratory Pressure (BBPEP) Versus Acapella Among Patient With Chronic Bronchitis
Comparison of Blow Bottle Positive Expiratory pressure(BBPEP)versus acapella on Oxygenation ,peak Expiratory Flow Rate(PEFR)among patient with chronic bronchitis.
- Trial name
- NCT06086730
- Testing
- blow bottle positive expiratory pressure, acapella
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Obstructive Sleep Apnea
Head to Head Comparison of Upper Airway Stimulation and Continuous Positive Airway Pressure; a Pilot Study.
To date, there has been no head to head comparison of Upper Airway Stimulation (UAS) and Continuous Positive Airway Pressure (CPAP) utilizing a full night polysomnographic evaluation.
- Trial name
- NCT04191512
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Premature Birth
E-23596 - Use of NCPAP Cycling to Wean Preterm Infants
Objective: To compare the effectiveness of nasal continuous positive airway pressure (NCPAP) cycling to continuous NCPAP in successful weaning of preterm infants of 25-28 weeks gestation to nasal prongs.
- Trial name
- NCT02114112
- Testing
- NCPAP cycling, NCPAP continuous
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Obstructive Sleep Apnea
Promoting the Use of CPAP Therapy Among OSA Patients
Obstructive sleep apnea (OSA) is the most common sleep breathing disorder in the U.S. Continuous Positive Airway Pressure (CPAP) therapy is the most effective treatment for OSA.
- Trial name
- NCT04372329
- Testing
- CPAP4HealthySleep system
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sarah Alismail
Obstructive Sleep Apnea
Validation and Reproducibility of the Six-minute Step Test in Individuals With Obstructive Sleep Apnea Treated With CPAP
Introduction: The Obstructive Sleep Apnea (OSA) is characterized by obstructed superior airway during sleeping period promoting intermittent hypoxia-reoxygenation events.
- Trial name
- NCT03334331
- Testing
- Six-minute step test, Six-minute walk test
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Urinary Bladder Neoplasms, Prostatic Neoplasms
Effect of PEEP on Arterial Oxygen Partial Pressure in Elderly Patients With Lithotomy Position Using LMA Supreme™
The purpose of the present study is to compare the effect of PEEP on arterial oxygen partial pressure in elderly patients undergoing urologic surgery using LMA supreme™ in a lithotomy position.
- Trial name
- NCT03390127
- Testing
- PEEP
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Asan Medical Center
Sleep Apnea Syndromes
Efficiency of a Phone Coaching for Sleep Apnea Hypopnea Syndrome Patients
Background: Continuous Positive Airway Pressure (CPAP) remains the reference treatment for moderate to severe forms of the Sleep Apnea/Hypopnea Syndrome (SAHS).
- Trial name
- NCT02435355
- Testing
- telephone-based counselling
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Sadir Association
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive
Comparison Study of the ICON™ Auto Series With and Without SensAwake™ and ThermoSmart™ and Conventional Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients
A total of 216 patients will be randomized into a partially single blind, randomized, parallel-arm trial to determine whether the ICON™ AT with SensAwake™ and ThermoSmart™ can improve therapy adherence when compared to standard…
- Trial name
- NCT01517763
- Testing
- Conventional CPAP Therapy, Fixed pressure ICON™ without ThermoSmart™, Auto ICON™ with SensAwake™ and ThermoSmart™
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Fisher and Paykel Healthcare
Healthy
I-Gel Versus Disposable Laryngeal Mask (LMA) for General Anesthesia (GA) With Controlled Ventilation
Randomized controlled trial comparing performance of the I-gel and disposable Laryngeal Mask Airways under controlled ventilation. 200 patients, 100 in each arm. Measurement of peak airway and sealing pressures.
- Trial name
- IGE(L)MA (NCT00668278)
- Testing
- Insertion of laryngeal mask airway (AuraOnce mask), Insertion of I-gel airway, Measurement of airway pressures
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northern Health and Social Care Trust
Airway Disease
Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy
Introduction: The non-invasive ventilation (NIV) of continuous nasopharyngeal O2 with intermittent close/open nose and abdomen compression (PO2-NC-AC) can provide effective oxygenation, ventilation and circulation.
- Trial name
- NCT03666403
- Testing
- NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
CO2 Clearance, Mask Comfort
Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers
This study will be a randomized crossover trial that will be conducted at Rush University. The study will be conducted with 20 healthy volunteers who will be placed on ICU ventilator operating in the NIPPV mode.
- Conditions
- CO2 Clearance, Mask Comfort, Rebreathing Exhaled Gas
- Trial name
- NCT03882723
- Testing
- Evaluated 4 masks used for NIV with mechanical ventilators
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Obstructive Sleep Apnoea
The Use of Oral Appliances as an Adjunct to Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnoea
This study will look at whether patients with OSAHS already successfully treated with nasal CPAP could successfully use an oral appliance as a short-term treatment alternative and whether patients who could use an oral appliance…
- Trial name
- NCT00358605
- Testing
- The Klearway™ oral appliance
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants
Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates
Oral feeding of neonates while on nasal continuous positive airway pressure (NCPAP) is a common practice in many neonatal intensive care units (NICU) all over the country.
- Conditions
- Deglutition Disorders, Respiratory Distress Syndrome In Premature Infants, Respiratory Aspiration, Newborn, Premature
- Trial name
- NCT02661256
- Testing
- NCPAP, Varibar® Thin Liquid Barium Sulfate for Suspension
- Volunteers
- 7 people
- Sponsor
- NYU Langone Health
Hypoxemia
SuperNO2VA Et Versus Oxygen Face Mask During Deep Sedation
The primary objective of the study is to prospectively and randomly compare the incidence, duration, and severity of oxygen desaturation between a nasal mask with nasal positive airway pressure (PAP) versus oxygen therapy with a…
- Trial name
- iOXYGENATE (NCT05175573)
- Testing
- SuperNO2VA Et Nasal Positive Pressure Mask, Supplemental Oxygen Face Mask
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Vyaire Medical
Nasopharyngeal Airway Pressure
Nasopharyngeal Pressure Measurement During Neonatal Nasal Respiratory Support
This study will measure nasopharyngeal pressure in neonates using a miniature high resolution catheter-tip pressure transducer. Any neonatal intensive care patient being treated with nasal respiratory support (e.g., nasal…
- Trial name
- NCT00766194
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Obstructive Sleep Apnea Syndrome
Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Continuous Positive Airway Pressure (CPAP) is the standard treatment in patients with Obstructive Sleep Apnea Syndrome (OSAS). The goal of the study is to evaluate CPAP treatment duration recorded by the AL539 during attended…
- Trial name
- AL539 (NCT01441622)
- Testing
- AL539 (SRETT)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Air Liquide Santé International
Obstructive Sleep Apnea, Cardiovascular Disease
Cardiovascular Effects After CPAP Withdrawal for Obstructive Sleep Apnea
Background: Patients with obstructive sleep apnea run an increased risk of cardiovascular disease including hypertension. Continuous positive airway pressure (CPAP) is the first line of treatment.
- Trial name
- NCT02329470
- Testing
- Withdrawal of continuous positive airway pressure treatment
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Postoperative Airway Complications
The Impact of Endotracheal Cuff Pressure Assessment Using a Cuff Pressure Manometer Compared With the Traditional Palpation Method on Postoperative Outcomes
The aim of this prospective observational study is to evaluate the effect of endotracheal cuff pressure management on postoperative complications in patients undergoing surgery under general anesthesia.
- Trial name
- ECP (NCT07427173)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep