Clinical trials: Airway Pressure
Cardiac Congenital Defects
Volume Versus Pressure Ventilation on Lung Atelectasis
This prospective randomized comparative study, to assess post-operative lung atelectasis by comparing calculated lung score using ultrasound between pediatric patients intubated with LMA (laryngeal mask airway) under volume…
- Trial name
- NCT06076395
- Testing
- LMA (Laryngeal Mask Airway)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Feeding Behavior, Chronic Lung Disease
Pilot Study Comparing Different Modes of Non-invasive Ventilation for the Oral Feeding of Preterm Infants
Preterm infants born before 28 weeks gestation are at risk for lung disease and require oxygen and pressure to keep their lungs open. This usually involves a device called nasal continuous positive airway pressure (nCPAP).
- Trial name
- CHOMP (NCT02055339)
- Testing
- Fisher & Paykel heated humidified high flow nasal cannula, InfantFlow/RAM nasal continuous positive airway pressure
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Mount Sinai Hospital, Canada
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Hyperinflation
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Brief Summary People with severe chronic obstructive pulmonary disease (COPD) often have too much air trapped in their lungs (pulmonary hyperinflation). This makes it hard to breathe and reduces quality of life.
- Trial name
- SIMEO-RV COPD (NCT07665931)
- Testing
- Simeox
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Parkinson's Disease, Sleep Disordered Breathing
Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease
The purpose of this study is to determine the impact of sleep and breathing problems during sleep on memory, attention, and general well being (quality of life) in people with Parkinson Disease.
- Conditions
- Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
- Trial name
- NCT02034357
- Testing
- Neurocognitive function, Sleep evaluations
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Miami
Obstructive Sleep Apnea
The Effect of Positive Airway Pressure on Heart Rate Variability
This study is designed to determine the effect of continuous positive airway pressure (CPAP) or bi-level positive airway pressure (BiPAP) on heart rate variability (HRV) in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT00289666
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Christiana Care Health Services
Obstructive Sleep Apnea
Effects of Continuous Positive Airway Pressure Therapy Withdrawal in Patients With Obstructive Sleep Apnea: A Randomized Trial
Study design (e.g., double-blind: A randomized, open-labeled, controlled, parallel-group study. Sixty patients will be recruited with moderate to severe Obstructive Sleep Apnea (OSA), previously adherent to CPAP therapy and have…
- Trial name
- NCT05471765
- Testing
- Withdrawal of Continuous Positive Airway Pressure device, Alternation usage of Continuous Positive Airway Pressure Device
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdulaziz University
Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy
Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial
Acute hypoxemic respiratory failure (AHRF) is a common indication for admission to an intensive care unit (ICU), with mortality exceeding 50% in cases where invasive mechanical ventilation is needed.
- Conditions
- Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP)
- Trial name
- TRIPOD (NCT06795971)
- Testing
- Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Southeast University, China
One-Lung Ventilation, Thoracic Surgery, Video-Assisted
Comparison Between CPAP and HFJV During One-lung Ventilation in VATS
This study compares two ventilatory techniques (continuous positive airway pressure vs high frequency jet ventilation) during one-lung ventilation (OLV) in video-assisted thoracic surgery (VATS).
- Trial name
- NCT03296449
- Testing
- CPAP, HFJV
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario de Alicante
Sleep Apnea, Obstructive
Trazodone Dose Tolerance and APAP Adherence
Trazodone may help obstructive sleep apnea patients to stick to their therapy, but optimal dosing is unknown. This study looks at what dose of trazodone has the best balance of potential benefits to side-effects in people with…
- Trial name
- TrazoDose (NCT02945644)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Louis Stokes VA Medical Center
Obstructive Sleep Apnea
Effect of CPAP Treatment in Cognition in Adults With DS and OSA
Adults with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA), which may worsen cognitive performance. In general population, continuous positive airway pressure (CPAP), the gold Standard treatment for…
- Trial name
- NCT04198493
- Testing
- CPAP, CONSERVATIVE TREATMENT for OSA
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obstruction Airway
Positive Airway Pressure (PAP) System Evaluation in Volunteers
This study will test the control and measurements of a new system for airway support in healthy volunteers. The goals of the study are to evaluate how accurately the system can stabilize airway pressure to a desired level…
- Trial name
- NCT07246538
- Testing
- CPAP
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Utah
Down Syndrome, Obstructive Sleep Apnea
Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)
Determine the efficacy of family-informed intervention (INT) vs standard clinical care over a period of twelve months in children with obstructive sleep apnea and Down Syndrome.
- Trial name
- NCT04132999
- Testing
- Family-informed intervention, Standard Clinical Care
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Miami
COVID-19
Clinical and Electronic Record for Patients With COVID-19 Treated With the Assisted Breathing Helmet - ELMO in Ceará
Continuous positive airway pressure (CPAP) with a helmet-like interface has been described as a safe strategy, with minimal contamination of the environment, improving the oxygenation of patients with acute respiratory failure…
- Trial name
- COVID-19 (NCT05375799)
- Testing
- Clinical Observation
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- Escola de Saúde Pública do Ceará
Preterm Birth, Extreme Prematurity
Sustained Aeration of Infant Lungs Trial
This study is a 2-arm randomized, controlled, multi-center clinical trial to determine which of two strategies at birth are best to optimally aerate the lung of preterm infants.
- Trial name
- SAIL (NCT02139800)
- Testing
- Sustained Inflation, Standard of Care
- Where
- 21 sites in United States, Australia and 7 more
- Volunteers
- 460 people
- Sponsor
- University of Pennsylvania
Respirtory Distress
Study of the Effects of CPAP and HHHFNC on Diaphragmatic Dimensions in Preterm Infants
This is a prospective, randomized crossover study to recognize the effects of nasal continuous positive airway pressure (CPAP) versus heated humidified high flow nasal cannula (HHHFNC) on diaphragmatic dimensions and excursion…
- Trial name
- NCT02421328
- Testing
- CPAP first (Fisher & Paykel Healthcare), HHHFNC first (Fisher & Paykel Healthcare)
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University Children Hospital
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
Introduction: It is unclear whether exercise training with or without Continuous Positive Airway Pressure (CPAP) and Oral Appliance (OA) is more effective in reducing symptoms of Obstructive Sleep Apnea (OSA) than treatment…
- Trial name
- NCT01289392
- Testing
- Continuous Positive Airway Pressure (CPAP), Oral Appliance (OA), Physical Exercise
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Type 1 Diabetes, Sleep Apnea Syndrome
Effect of Sleep Apnea Treatment on Type 1 Diabetes
Hypothesis: To address the role of continuous positive airway pressure (CPAP)on nocturnal glycemia in patients having type 1 diabetes and sleep apnea syndrome.
- Trial name
- DIADEME (NCT02316665)
- Testing
- continuous positive airway pressure
- Where
- France
- Volunteers
- 81 people
- Sponsor
- University Hospital, Grenoble
Respiratory Distress Syndrome, Newborn
Intrapulmonary Percussive Ventilation (IPV) Versus Nasal Continuous Positive Airway Pressure Ventilation (nCPAP) in Transient Respiratory Distress of the Newborn
During caesarean section, transient respiratory distress which occurs frequently (3%) with possible complications are at present managed by non invasive nasal continuous positive airway pressure ventilation (nCPAP) associated…
- Trial name
- HFPV (NCT00556738)
- Testing
- Nasal Continuous Positive Airway Pressure ventilation, Intrapulmonary Percussive Ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Obstructive Sleep Apnea
PAP-NAP Device Clinical Study
This exploratory pilot study will evaluate the usability and short-term tolerability of a novel positive airway pressure (PAP) device in adults during a supervised daytime nap session in a simulated sleep environment.
- Trial name
- NCT07785310
- Testing
- APL Device
- Volunteers
- 10 people
- Sponsor
- ResMed
Hypertension, Obstructive Sleep Apnea
Renal Denervation in Patients With Resistant Hypertension and Obstructive Sleep Apnea
The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of resistant hypertension coexisting with obstructive sleep apnea.
- Trial name
- NCT01366625
- Testing
- Renal denervation with a catheter-based procedure (Symplicity® Catheter System)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland